Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Evan Lind"'
Autor:
Patrick Flynn, Yoko Kosaka, Matthew Newman, Kyle Romine, Hyun-Jun Cho, Kaelan Byrd, Jesse Coy, Christopher Loo, Evan Lind
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/59f3b261c10142a1a090779f8425025e
Autor:
Haijiao Zhang, Samantha Savage, Anna Reister Schultz, Daniel Bottomly, Libbey White, Erik Segerdell, Beth Wilmot, Shannon K. McWeeney, Christopher A. Eide, Tamilla Nechiporuk, Amy Carlos, Rachel Henson, Chenwei Lin, Robert Searles, Hoang Ho, Yee Ling Lam, Richard Sweat, Courtney Follit, Vinay Jain, Evan Lind, Gautam Borthakur, Guillermo Garcia-Manero, Farhad Ravandi, Hagop M. Kantarjian, Jorge Cortes, Robert Collins, Daelynn R. Buelow, Sharyn D. Baker, Brian J. Druker, Jeffrey W. Tyner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
FLT3 is commonly mutated in acute myeloid leukaemia and treatment with FLT3 inhibitors often ends with relapse. Here, the authors perform exome sequencing of samples from patients treated with the FLT3 inhibitor, crenolanib, to show that resistance o
Externí odkaz:
https://doaj.org/article/998f439604e74cef95464ecda676fa5a
Autor:
Samit Chatterjee, Laurie Seifried, Michael E Feigin, Don L Gibbons, Claudio Scuoppo, Wei Lin, Zain H Rizvi, Evan Lind, Dilan Dissanayake, Jonathan Kurie, Pam Ohashi, Senthil K Muthuswamy
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34343 (2012)
Changes in expression and localization of proteins that regulate cell and tissue polarity are frequently observed in carcinoma. However, the mechanisms by which changes in cell polarity proteins regulate carcinoma progression are not well understood.
Externí odkaz:
https://doaj.org/article/90a1cd0096e04306b3d2cda5a724962d
Autor:
Olivia M. Lucero, Ji-Ann Lee, Jenna Bowman, Kara Johnson, Gopal Sapparapu, John K. Thomas, Guang Fan, Bill H. Chang, Karina Thiel-Klare, Christopher A. Eide, Craig Okada, Mike Palazzolo, Evan Lind, Yoko Kosaka, Brian J. Druker, Nicholas Lydon, Peter M. Bowers
Publikováno v:
Clinical Cancer Research.
Purpose: Targeted therapeutics are a goal of medicine. Methods for targeting T-cell lymphoma lack specificity for the malignant cell, leading to elimination of healthy cells. The T-cell receptor (TCR) is designed for antigen recognition. T-cell malig
Autor:
Kyle Romine, Hyun-jun Cho, Yoko Kosaka, Patrick Flynn, Kaelan Byrd, Jesse Coy, Matthew Newman, Jamie Scott, Andrew Adey, Evan Lind
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
The Journal of Immunology. 208:61.17-61.17
Acute myeloid leukemia (AML) is a hematological cancer with a very poor prognosis. FLT3-ITD mutations that cause constitutive FLT3 signaling are commonly seen in patients. Our lab and others have shown that AML patient samples exhibit hallmarks of im
Autor:
Patrick A Flynn, Evan Lind
Publikováno v:
The Journal of Immunology. 206:101.12-101.12
Acute myeloid leukemia (AML) is a hematological cancer with a very poor prognosis. FLT3-ITD mutations, which result in constitutive FLT3 signaling, are the most common mutation. Our lab and others have shown that many AML patient samples exhibit hall
Autor:
Kyle Alexander Romine, Hyun-jun Cho, Yoko Kosaka, Patrick Flynn, Jesse Coy, Kaelan Byrd, Matthew Newman, Evan Lind
Publikováno v:
The Journal of Immunology. 206:67.01-67.01
Acute myeloid leukemia (AML) is an aggressive myeloid lineage white blood cell cancer with an extremely poor prognosis that occurs most frequently above 60 years of age. The current standard of care consists of an intensive induction chemotherapy reg
Autor:
Patrick A Flynn, Evan Lind
Publikováno v:
The Journal of Immunology. 204:229.9-229.9
miR-146a is a micro-RNA that acts on transcripts upregulated in response to TLR induced signaling. Activation of TLRs results in maturation and survival of dendritic cells (DCs) to prime T cells. Interestingly, little is known how miR-146a regulates
Publikováno v:
Cancer Research. 79:1340-1340
Introduction Acute myeloid leukemia (AML) is a deadly disease associated with high mortality and morbidity. Previous studies report defects in NK cell maturation and function in AML patients leading to innate immune evasion. Considering that the numb