Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Evan L. Riddle"'
Publikováno v:
European Journal of Pharmacology. 571:25-28
High-dose administration of psychostimulants traffics the vesicular monoamine transporter-2 (VMAT-2), as assessed by subcellular fractionation of rat striatal tissue. This study demonstrates that administration of low doses of amphetamine or methylph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74517e4245132bdbbfb3db75dc688364
https://doi.org/10.1016/j.ejphar.2007.05.044
https://doi.org/10.1016/j.ejphar.2007.05.044
Autor:
Kenton K. Murthy, Evan L. Riddle, Fangwen Rao, Daniel T. O'Connor, Paul A. Insel, Eleazar Eskin, Brinda K. Rana
Publikováno v:
Hypertension. 47:415-420
Regulator of G protein signaling (RGS) proteins stimulate the GTPase activity of G α subunits of heterotrimeric G proteins, thereby negatively regulating G protein-coupled receptor signaling. RGS2, which preferentially alters G αq -mediated signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d7bfd4fd39a485ea348f1921e94721
https://doi.org/10.1161/01.hyp.0000200714.81990.61
https://doi.org/10.1161/01.hyp.0000200714.81990.61
Publikováno v:
The AAPS Journal. 7:E847-E851
Monoamine transporters such as the dopamine (DA) transporter (DAT) and the vesicular monoamine transporter-2 (VMAT-2) are critical regulators of DA disposition within the brain. Alterations in DA disposition can lead to conditions such as drug addict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56e25ffce7e1d6d2d73dda107cb8d73
https://doi.org/10.1208/aapsj070481
https://doi.org/10.1208/aapsj070481
Publikováno v:
Circulation Research. 96:401-411
Regulator of G-protein–signaling (RGS) proteins play a key role in the regulation of G-protein–coupled receptor (GPCR) signaling. The characteristic hallmark of RGS proteins is a conserved ≈120-aa RGS region that confers on these proteins the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0630b54b8056626a14ea92257d4f605
https://doi.org/10.1161/01.res.0000158287.49872.4e
https://doi.org/10.1161/01.res.0000158287.49872.4e
Publikováno v:
Annals of the New York Academy of Sciences. 1025:146-150
The monoamine vesicular transporter 2 (VMAT-2) has been associated with dopamine (DA) sequestration and protection against neurodegeneration caused by the intracellular oxidation of this monoamine. The data presented herein suggest that methylphenida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d8f038d062417ef8faa052a52237f1
https://doi.org/10.1196/annals.1316.019
https://doi.org/10.1196/annals.1316.019
Publikováno v:
The Journal of Neuroscience. 24:3436-3443
Multiple high-dose administrations of methamphetamine (METH) both rapidly (within hours) decrease plasmalemmal dopamine (DA) uptake and cause long-term deficits in DA transporter (DAT) levels and other dopaminergic parameters persisting weeks to mont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f432ffaf0973b98a94e09f22be0788de
https://doi.org/10.1523/jneurosci.0387-04.2004
https://doi.org/10.1523/jneurosci.0387-04.2004
Publikováno v:
The Journal of Neuroscience. 22:8705-8710
It is well accepted that methylphenidate (MPD) inhibits dopamine (DA) transporter function. In addition to this effect, this study demonstrates that MPD increases vesicular [3H]DA uptake and binding of the vesicular monoamine transporter-2 (VMAT-2) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e6e9fcfdbd7470fc3def12236dfc58
https://doi.org/10.1523/jneurosci.22-19-08705.2002
https://doi.org/10.1523/jneurosci.22-19-08705.2002
Autor:
James W. Gibb, Annette E. Fleckenstein, Verónica Sandoval, Jeffrey M. Brown, Jarom E. Hanson, Raul K. Weston, Michael J. Crosby, Yvette V. Ugarte, Evan L. Riddle, Glen R. Hanson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 302:497-501
Recent studies demonstrated that vesicular dopamine (DA) uptake can be rapidly altered in synaptic vesicles purified from the striata of stimulant-treated rats. Specifically, a single administration of the plasmalemmal DA transporter inhibitor, cocai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fd948dd51260e622aaa5240fead266
https://doi.org/10.1124/jpet.302.2.497
https://doi.org/10.1124/jpet.302.2.497
Publikováno v:
The Journal of Neuroscience. 21:1413-1419
This laboratory has demonstrated that a single methamphetamine (METH) injection rapidly and reversibly decreases the activity of the dopamine transporter (DAT), as assessedex vivoin synaptosomes prepared from treated rats. This decrease does not occu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c7fcb625203973d98b6dcca2c26afc
https://doi.org/10.1523/jneurosci.21-04-01413.2001
https://doi.org/10.1523/jneurosci.21-04-01413.2001
Publikováno v:
Drug Addiction ISBN: 9780387766775
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d622480652a117e10b3cead78dc1c020
https://doi.org/10.1007/978-0-387-76678-2_11
https://doi.org/10.1007/978-0-387-76678-2_11
