Výsledky vyhledávání - "Evan L. Mulligan"

An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries

Autor: Jeremy R. Duvall, Jacob K. Asiedu, Paul A. Clemons, Lisa A. Marcaurelle, Willmen Youngsaye, Andrea de Souza, Evan L. Mulligan, Nicola Tolliday, Sivaraman Dandapani, Lakshmi B. Akella, Dennis Moccia, Michael Quintin, David L. Lahr, Stephen Brudz, Philip Montgomery, Carol A. Mulrooney, Joshua A. Bittker

Publikováno v: Journal of Computer-Aided Molecular Design. 27:455-468

Integration of flexible data-analysis tools with cheminformatics methods is a prerequisite for successful identification and validation of "hits" in high-throughput screening (HTS) campaigns. We have designed, developed, and implemented a suite of ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba9df66ba425ac3b50d00618fd9274f
https://doi.org/10.1007/s10822-013-9641-y

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High-Throughput Isolation of Caenorhabditis elegans Deletion Mutants

Autor: Leo X. Liu, Gary Hardiman, Ken Abel, Ralph Clover, Evan L. Mulligan, Michael Basson, Judith King, Barbara Armstrong, Jing Chen, Brian Reardon, Lin Sun, Lisa McCague, Bethany Westlund, Carl D. Johnson, Jill M. Spoerke

Publikováno v: Genome Research. 9:859-867

The rapid progress in genome sequencing projects has propelled a shift in genome analysis from structural genomics to functional genomics, that is, the genome-driven systematic study of gene function (Hieter and Boguski 1997). In this postgenomic era

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21ab8ac2cdbc546446719d6026327dd
https://doi.org/10.1101/gr.9.9.859

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Screen for MAOA mutations in target human groups

Autor: Chen-Yang Shen, Mei-Shang Ho, Benjamin D. Greenberg, Evan L. Mulligan, Deborah E. Schuback, Stephen P. Fink, Show Lin Yang, F. Berlin, Katherine B. Sims, Charles E. Schwartz, Elizabeth A. Tivol, Yun Pung Paul Hsu, Yi Chien Mau, Nan Hua Yang, Merlin G. Butler, Xandra O. Breakefield, Dennis L. Murphy, Shu Fen Chang

Publikováno v: American Journal of Medical Genetics. 88:25-28

Brunner et al. [1993: Am J Hum Genet 52: 1032-1039; 1993: Science 262:578-580] described males with an MAO-A deficiency state resulting from a premature stop codon in the coding region of the MAOA gene. This deficiency state was associated with abnor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8d909038ada0090891074ef14c391f
https://doi.org/10.1002/(sici)1096-8628(19990205)88:1<25::aid-ajmg4>3.0.co

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The Mouse Gene Encoding the Testis-Specific Isoform of Poly(A) Binding Protein (Pabp2) Is an Expressed Retroposon: Intimations That Gene Expression in Spermatogenic Cells Facilitates the Creation of New Genes

Autor: Kevin Donohue, Daniel Steiger, Mary-Ann Mastrangelo, Kenneth C. Kleene, Evan L. Mulligan

Publikováno v: Journal of Molecular Evolution. 47:275-281

The gene encoding the testis-specific isoform of mouse poly(A) binding protein (Pabp2) has been isolated and sequenced. Unexpectedly, comparison of the sequence of genomic and cDNAs demonstrated that the Pabp2 gene lacks introns, whereas all other fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81d66c007b78134b17debb668bb578b
https://doi.org/10.1007/pl00006385

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