Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Evan Herlihy"'
Autor:
Drew Dudgeon, Xuan Ye, Jacqueline J. Warsaw, Evan Herlihy, Erica Ullman, Arpita Pawashe, William Poueymirou, Patrick Poon, Ilyssa Ramos, Dharani Ajithdoss, Bei Wang, Jacquelynn Golubov, Nicole Stokes Oristian, Eric Smith, Matthew A. Sleeman, George D. Yancopoulos, Rabih Slim, Alison Crawford, Priyanka Ram, William C. Olson, Chia-Jen Siao, Andrew J. Murphy, Hassan Ahmed, Terra Potocky, Janelle C. Waite, Danica Chiu, Gavin Thurston, Dimitris Skokos, Tammy T. Huang, Erin Oswald, Lauren Canova, Adelekan Oyejide, Stephen Godin, Lauren Havel, Kathleen Provoncha, Qi Wu, Douglas MacDonald, Miguel Lazo, Kevin Yu, Joel H. Martin, Ashique Rafique, Kristin Vazzana, John C. Lin, Lauric Haber, Jessica R. Kirshner, Aynur Hermann, Julie Kim
Publikováno v:
Science Translational Medicine. 12
T cell activation is initiated upon binding of the T cell receptor (TCR)/CD3 complex to peptide-major histocompatibility complexes ("signal 1"); activation is enhanced by engagement of a second "costimulatory" receptor, such as the CD28 receptor on T
Autor:
Shao Ning Yang, Rabih Slim, Lauren Canova, Andrew J. Murphy, Macdonald Lynn, Jacqueline J. Warsaw, Cagan Gurer, Erica Ullman, Arpita Pawashe, Lauric Haber, Aynur Hermann, Ilyssa Ramos, Gang Chen, Jennifer Stella, Jacquelynn Golubov, Teresa Schulenburg, George D. Yancopoulos, Joel H. Martin, Jennifer Finney, Dimitris Skokos, Ashique Rafique, Elizabeth Navarro, Matthew A. Sleeman, Elena Garnova, Nicole Stokes Oristian, Robert Babb, Xuan Ye, Randi Foster, Julie Kim, William Poueymirou, Qi Wu, Douglas MacDonald, Hassan Ahmed, William C. Olson, Clarissa Lett, Erin Oswald, Janelle C. Waite, Israel Lowy, Stephen Godin, Eric Smith, Pamela Krueger, Devon Grote, Patrick Poon, John C. Lin, Drew Dudgeon, Evan Herlihy, Bei Wang, Amanda Dorvilliers, Dharani Ajithdoss, Jenny Xiao, Christopher Daly, Vishal Kamat, Gavin Thurston, Chia-Jen Siao
Publikováno v:
Science translational medicine. 12(549)
Monoclonal antibodies that block the programmed cell death 1 (PD-1) checkpoint have revolutionized cancer immunotherapy. However, many major tumor types remain unresponsive to anti-PD-1 therapy, and even among responsive tumor types, most of the pati
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:2187-2194
The folate receptor (FR) has been widely recognized as an excellent target for the tumor-selective delivery of cytotoxic agents, and four folate-drug conjugates have entered clinical evaluations for the treatment of solid tumors to date. However, mos