Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Evan F. Garner"'
Autor:
Adele P. Williams, Evan F. Garner, Laura L. Stafman, Jamie M. Aye, Colin H. Quinn, Raoud Marayati, Jerry E. Stewart, Venkatram R. Atigadda, Elizabeth Mroczek-Musulman, Blake P. Moore, Elizabeth A. Beierle, Gregory K. Friedman
Publikováno v:
Translational Oncology, Vol 12, Iss 10, Pp 1364-1374 (2019)
PURPOSE: In spite of advances in therapy for some subtypes, group 3 medulloblastoma continues to portend a poor prognosis. A subpopulation of medulloblastoma cells expressing the cell surface marker CD133 have been posited as possible stem cell like
Externí odkaz:
https://doaj.org/article/798dcfd1d04e44b4aa17ab1120ac63b9
Autor:
Laura L. Stafman, Adele P. Williams, Raoud Marayati, Jamie M. Aye, Hooper R. Markert, Evan F. Garner, Colin H. Quinn, Shoeb B. Lallani, Jerry E. Stewart, Karina J. Yoon, Kimberly Whelan, Elizabeth A. Beierle
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Patient-derived xenografts (PDXs) provide an opportunity to evaluate the effects of therapies in an environment that more closely resembles the human condition than that seen with long-term passage cell lines. In the current studies, we inve
Externí odkaz:
https://doaj.org/article/ae4c4e6cac14422ea46500505cb9f16e
Autor:
Laura L. Stafman, Adele P. Williams, Evan F. Garner, Jamie M. Aye, Jerry E. Stewart, Karina J. Yoon, Kimberly Whelan, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 12, Iss 2, Pp 200-208 (2019)
Hepatoblastoma is the most common primary liver tumor in children, but treatment has not changed significantly in the past 20 years. We have previously demonstrated that Proviral Integration site for Moloney murine leukemia (PIM) kinases promote tumo
Externí odkaz:
https://doaj.org/article/50eba423670a4f4380c1edd4eb9fdaa0
Autor:
Adele P. Williams, Evan F. Garner, Alicia M. Waters, Laura L. Stafman, Jamie M. Aye, Hooper Markert, Jerry E. Stewart, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 84-95 (2019)
High-risk neuroblastoma continues to carry a poor prognosis. Nearly 50% of these tumors relapse following extensive treatment regimens. Protein phosphatase 2A (PP2A), a tumor suppressor, has been shown to be downregulated in many human cancers via mu
Externí odkaz:
https://doaj.org/article/e301bf95fdb34b2097d8ae0defd2aedc
Autor:
Evan F. Garner, Adele P. Williams, Laura L. Stafman, Jamie M. Aye, Elizabeth Mroczek-Musulman, Blake P. Moore, Jerry E. Stewart, Gregory K. Friedman, Elizabeth A. Beierle
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Group 3 tumors account for 28% of medulloblastomas and have the worst prognosis. FTY720, an immunosuppressant currently approved for treatment of multiple sclerosis, has shown antitumor effects in several human cancer cell lines. We hypothes
Externí odkaz:
https://doaj.org/article/60d3b17a2b504ab498e8b0462588e830
Autor:
Alicia M. Waters, Laura L. Stafman, Evan F. Garner, Smitha Mruthyunjayappa, Jerry E. Stewart, Gregory K. Friedman, Jennifer M. Coleman, James M. Markert, G. Yancey Gillespie, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 9, Iss 5, Pp 419-430 (2016)
Rhabdomyosarcoma (RMS), a tumor of skeletal muscle origin, is the most common sarcoma of childhood. Despite multidrug chemotherapy regimens, surgical intervention, and radiation treatment, outcomes remain poor, especially in advanced disease, and nov
Externí odkaz:
https://doaj.org/article/6e4edd8f93794346a21f1fb0ce62b1fe
Autor:
Alicia M. Waters, Laura L. Stafman, Evan F. Garner, Smitha Mruthyunjayappa, Jerry E. Stewart, Elizabeth Mroczek-Musulman, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 9, Iss 4, Pp 263-273 (2016)
Despite the tremendous advances in the treatment of childhood solid tumors, rhabdomyosarcoma (RMS) continues to provide a therapeutic challenge. Children with metastatic or relapsed disease have a disease-free survival rate under 30%. Focal adhesion
Externí odkaz:
https://doaj.org/article/b5bd3aaff2064b53b27bfa1b1025c3f5
Autor:
Michael I. Brener, Mohanad Hamandi, Estee Hong, Alejandro Pizano, Morgan T. Harloff, Evan F. Garner, Abdallah El Sabbagh, Ryan K. Kaple, Arnar Geirsson, David W. Deaton, Ashequl M. Islam, Ramesh Veeregandham, Vinayak Bapat, Omar K. Khalique, Yuming Ning, Paul A. Kurlansky, Paul A. Grayburn, Tamim M. Nazif, Susheel K. Kodali, Martin B. Leon, Michael A. Borger, Raymond Lee, Keshav Kohli, Ajit P. Yoganathan, Andrea Colli, Mayra E. Guerrero, James E. Davies, Kyle W. Eudailey, Tsuyoshi Kaneko, Tom C. Nguyen, Hyde Russell, Robert L. Smith, Isaac George
Publikováno v:
The Journal of thoracic and cardiovascular surgery.
Implantation of a transcatheter valve-in-mitral annular calcification (ViMAC) has emerged as an alternative to traditional surgical mitral valve (MV) replacement. Previous studies evaluating ViMAC aggregated transseptal, transapical, and transatrial
Autor:
Joshua C. Anderson, Caroline D. Goolsby, Kimberly Whelan, Elizabeth Mroczek-Musulman, Jamie M. Aye, Jerry E. Stewart, Raoud Marayati, Elizabeth A. Beierle, Evan F. Garner, Hooper R. Markert, Adele P. Williams, Colin H. Quinn, Christopher D. Willey, Karina J. Yoon, Mary G. Waldrop, Laura L. Stafman, Smitha Mruthyunjayappa
Publikováno v:
Oncotarget
Aggressive therapies for patients with metastatic Wilms tumor (WT) with subsequent severe late effects warrant the search for novel therapies. The role of focal adhesion kinase (FAK), a non-receptor tyrosine kinase important in pediatric solid tumor
Autor:
Adele P. Williams, Laura L. Stafman, Kimberly Whelan, Jerry E. Stewart, Elizabeth A. Beierle, Jamie M. Aye, Evan F. Garner, Karina J. Yoon
Publikováno v:
Translational Oncology, Vol 12, Iss 2, Pp 200-208 (2019)
Hepatoblastoma is the most common primary liver tumor in children, but treatment has not changed significantly in the past 20 years. We have previously demonstrated that Proviral Integration site for Moloney murine leukemia (PIM) kinases promote tumo