Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Evan F. Fullerton"'
Publikováno v:
J Neurosci
Opioids have decreased analgesic potency (but not efficacy) in aged rodents compared with adults; however, the neural mechanisms underlying this attenuated response are not yet known. The present study investigated the impact of advanced age and biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7f085123b1382cafb439219af5af38
https://doi.org/10.1523/jneurosci.0355-22.2022
https://doi.org/10.1523/jneurosci.0355-22.2022
The analgesic effects of opioids are attenuated in aged rats. Opioids such as morphine have decreased analgesic potency (but not efficacy) in aged rodents compared to adults; however, the neural mechanisms underlying this attenuated response are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e335a71ca523c9898365fba567887b4
https://doi.org/10.1101/2022.01.13.475945
https://doi.org/10.1101/2022.01.13.475945
Publikováno v:
The Journal of Pain. 23:39-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795d45a477540a70d7824fae6eb8070d
https://doi.org/10.1016/j.jpain.2022.03.152
https://doi.org/10.1016/j.jpain.2022.03.152
Autor:
Lamiyah F. Mussaji, Arlene J. George, Elara M. Ruszkowski, Alexandra Castillo-Ruiz, Andrew J. Jacobs, Andrew T. Gewirtz, Morgan Mosley, Nancy G. Forger, Benoit Chassaing, Evan F. Fullerton
Publikováno v:
Brain, Behavior, and Immunity. 67:218-229
The mammalian fetus develops in a largely sterile environment, and direct exposure to a complex microbiota does not occur until birth. We took advantage of this to examine the effect of the microbiota on brain development during the first few days of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8305267379a835984d55018674ed7a15
https://doi.org/10.1016/j.bbi.2017.08.027
https://doi.org/10.1016/j.bbi.2017.08.027
Publikováno v:
Current opinion in behavioral sciences. 23
Chronic pain is a debilitating condition that impacts tens of millions each year, resulting in lost wages for workers and exacting considerable costs in health care and rehabilitation. A thorough understanding of the neural mechanisms underlying pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b64fe2e113496addb8e5e10130ccb18
https://pubmed.ncbi.nlm.nih.gov/30906823
https://pubmed.ncbi.nlm.nih.gov/30906823
Publikováno v:
The Journal of Pain. 22:591
Chronic pain is under-managed in individuals over 65 years of age due to a dearth of knowledge regarding the impact of age on opioid efficacy in the elderly. We have previously shown that advanced age and sex alter morphine modulation of persistent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fc264655fac02738e44e3ef2ecdb9e8
https://doi.org/10.1016/j.jpain.2021.03.054
https://doi.org/10.1016/j.jpain.2021.03.054