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Publikováno v:
Journal of the Academy of Consultation-Liaison Psychiatry. 62:115-118
Immune checkpoint inhibitor (ICI) therapy offers an efficacious and novel way to treat many types of cancer. ICIs upregulate the immune system (specifically T-lymphocytes) allowing for better recognition and termination of neoplastic cells. 1 Adverse
Publikováno v:
Neuro Oncol
BACKGROUND Lynch syndrome (LS) and constitutional mismatch repair deficiency syndrome (CMMRD) are caused by germline mutations in mismatch repair (MMR) genes, namely MLH1, MSH2, MSH6, and PMS2. LS patients have an inherited mono-allelic MMR defect, w