Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Evan Dale Abel"'
Autor:
Manoja K. Brahma, Chae‐Myeong Ha, Mark E. Pepin, Sobuj Mia, Zhihuan Sun, John C. Chatham, Kirk M. Habegger, Evan Dale Abel, Andrew J. Paterson, Martin E. Young, Adam R. Wende
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 15 (2020)
Background Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects. The failing heart in nondiabetics tends to decrease reliance on fatty acid and glucose oxid
Externí odkaz:
https://doaj.org/article/0690fe8d35c040cc85c04ea9e3298c31
Autor:
Juhee Shin, Seok Hong Lee, Min-Chul Kwon, Dong Kwon Yang, Ha-Rim Seo, Jaetaek Kim, Yoon-Young Kim, Sun-Kyoung Im, Evan Dale Abel, Kyong-Tai Kim, Woo Jin Park, Young-Yun Kong
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53577 (2013)
Mitochondria are key organelles dedicated to energy production. Crif1, which interacts with the large subunit of the mitochondrial ribosome, is indispensable for the mitochondrial translation and membrane insertion of respiratory subunits. To explore
Externí odkaz:
https://doaj.org/article/4c8cbf04b21246659ad8b30804500836
Autor:
Alex Marti, Luis Miguel García-Peña, Matthew J. Potthoff, Eric T. Weatherford, Evan Dale Abel, Sarah Hartwick Bjorkman, Renata C. Pereira
Publikováno v:
Diabetes. 70
Short-term cold exposure induces the integrated stress response (ISR) and its main effector, the activating transcription factor 4 (ATF4), in brown adipose tissue (BAT). Furthermore, induction of ATF4 in BAT in response to mitochondrial stress is req
Autor:
Evan Dale Abel, John C. Chatham, Martin E. Young, Sobuj Mia, Adam R. Wende, Andrew J. Paterson, Zhihuan Sun, Manoja K. Brahma, Chae-Myeong Ha, Mark E Pepin, Kirk M. Habegger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects. The failing heart in nondiabetics tends to decrease reliance on fatty acid and glucose oxid
Autor:
Taylor L. Junck, Gourav Bhardwaj, Brian T. O’Neill, Kennedy Poro, Rhonda Souvenir, Pablo E. Morales, Jordan D. Fuqua, Collin M. Foster, Roberto Bravo-Sagua, Christie M. Penniman, Pablo A. Suarez Beltran, Antentor Othrell Hinton, Jayashree Jena, Vitor A. Lira, Evan Dale Abel
Publikováno v:
Diabetes. 69
Diabetes is associated with decreased muscle strength and mitochondrial metabolism which can lead to disability. Recently, we reported that insulin receptor (IR) and IGF-1 receptor (IGF1R) prevent muscle atrophy via suppression of FoxOs, but how FoxO
Autor:
Evan Dale Abel, Renata Pereira Alambert, Alayna Dieter, Renato Daniel Jensen, Joshua Peterson, Benjamin Allington, Marcelo L.G. Correia, Linhai Cheng, Jamie Soto
Publikováno v:
Journal of the Endocrine Society
The skeletal muscle of type 2 diabetics exhibits mitochondrial dysfunction associated with increased mitochondrial fission. Dynamin-related protein 1 (DRP1) is responsible for mitochondrial division, whereas mitochondrial-endoplasmic reticulum contac
Autor:
Robert A. Campbell, Rhonda Souvenir, Antentor Othrell Hinton, Alambert Renata, Matthew T. Rondina, Evan Dale Abel
Publikováno v:
Journal of the Endocrine Society
Thrombosis is a major concern in: premenopausal females on oral contraceptives, menopausal women undergoing hormone replacement therapy, post-menopausal women and transgender individuals receiving estrogen supplementation. The mechanisms linking estr
Publikováno v:
Journal of the Endocrine Society
Non-alcoholic steatohepatitis (NASH), a major complication of obesity, diabetes, and metabolic syndrome has emerged as a leading cause of chronic liver disease and a risk factor for hepatocellular carcinoma. Autophagy is a critical pathway for the de
Autor:
Evan Dale Abel, Katelyn Gerth, Andrew S. Weyrich, Trevor P. Fidler, Matthew T. Rondina, Alex P Marti
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Patients with type 1 diabetes mellitus (T1DM) have increased thrombosis and platelet activation. The mechanisms for platelet hyperactivation in diabetes are incompletely understood. T1DM is accompanied by hyperglycemia, hyperlipidemia, increased infl
Autor:
Jovan Kuzmicic, Andrea del Campo, Fabián Jaña, David A. Bernlohr, Camila López-Crisosto, Mario Chiong, Amira Klip, Christian Pennanen, Sergio Lavandero, Joseph A. Hill, Eduard Noguera, Yi Zhu, Valentina Parra, Rodrigo Troncoso, Myriam Iglewski, Antonio Zorzano, Hugo Verdejo, Beverly A. Rothermel, Deborah Jones, Evan Dale Abel, Jorge Ferreira
Publikováno v:
Diabetes
DIABETES
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
DIABETES
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Insulin regulates heart metabolism through the regulation of insulin-stimulated glucose uptake. Studies have indicated that insulin can also regulate mitochondrial function. Relevant to this idea, mitochondrial function is impaired in diabetic indivi