Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Evan D Trudeau"'
Publikováno v:
PLoS ONE, Vol 1, p e106 (2006)
BACKGROUND:In both Drosophila and the mouse, the zinc finger transcription factor Snail is required for mesoderm formation; its vertebrate paralog Slug (Snai2) appears to be required for neural crest formation in the chick and the clawed frog Xenopus
Externí odkaz:
https://doaj.org/article/632399255af846da9df2e1529c79c686
Autor:
Pei Hsuan Chu, Matthew E. Berginski, Andrei V. Karginov, Jason J. Yi, Klaus M. Hahn, Shawn M. Gomez, Denis Tsygankov, Timothy C. Elston, Evan D. Trudeau
Publikováno v:
Nature chemical biology
We describe an approach to selectively activate a kinase in a specific protein complex or at a specific subcellular location within living cells, and within minutes. This reveals the effects of specific kinase pathways without time for genetic compen
Autor:
Jason J. Yi, Timothy C. Elston, Denis Tsygankov, Shawn M. Gomez, Matthew E. Berginski, Andrei V. Karginov, Evan D. Trudeau, Klaus M. Hahn, Pei Hsuan Chu
Publikováno v:
Nature Chemical Biology. 10:692-692
Nat. Chem. Biol. 10, 286–290 (2014); published online 9 March 2014; corrected after print 7 April 2014 In the version of this article initially published online, the colors of the purple (SH2 mutant + FAK-FRB) and green (SH2 mutant + p130Cas-FRB) c
Autor:
Denis Tsygangov, Klaus M. Hahn, Pei Hsuan Chu, Shawn M. Gomez, Andrei V. Karginov, Evan D. Trudeau, Matthew E. Berginski, Timothy C. Elston, Jason J. Yi
Publikováno v:
Biophysical Journal. 104:161a
Activation of a kinase in a specific protein complex or subcellular location determines what signaling pathway will be initiated. Current methods typically cannot activate a specific kinase and simultaneously cause it to interact with one specific do