Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Evan C. Rosenberg"'
Autor:
Evan C. Rosenberg, Jocelyn J. Lippman-Bell, Marcus Handy, Samantha S. Soldan, Sanjay Rakhade, Cristina Hilario-Gomez, Kaitlyn Folweiler, Leah Jacobs, Frances E. Jensen
Publikováno v:
Neurobiology of Disease, Vol 116, Iss , Pp 120-130 (2018)
Neonatal seizures disrupt normal synaptic maturation and often lead to later-life epilepsy and cognitive deficits. During early life, the brain exhibits heightened synaptic plasticity, in part due to a developmental overabundance of CaV1.2 L-type vol
Externí odkaz:
https://doaj.org/article/52d81e84660a48ee9545b14b1a37b01b
Autor:
Evan C. Rosenberg, Simon Chamberland, Michael Bazelot, Erica R. Nebet, Xiaohan Wang, Sam McKenzie, Swati Jain, Stuart Greenhill, Max Wilson, Nicole Marley, Alejandro Salah, Shanice Bailey, Pabitra Hriday Patra, Rebecca Rose, Nicolas Chenouard, Simón(e) D. Sun, Drew Jones, György Buzsáki, Orrin Devinsky, Gavin Woodhall, Helen E. Scharfman, Benjamin J. Whalley, Richard W. Tsien
Publikováno v:
Neuron. 111:1282-1300.e8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68cc5a07d1cdf1bcc37730d9ba73c7b
https://doi.org/10.1016/j.neuron.2023.01.018
https://doi.org/10.1016/j.neuron.2023.01.018
Publikováno v:
Epilepsia. 58:e96-e100
Summary Recent clinical trials indicate that cannabidiol (CBD) may reduce seizure frequency in pediatric patients with certain forms of treatment-resistant epilepsy. Many of these patients experience significant impairments in quality of life (QOL) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b82ecec2ad5a88b1b013467327afc61
https://doi.org/10.1111/epi.13815
https://doi.org/10.1111/epi.13815
Autor:
Frances E. Jensen, Leah M. Jacobs, Sanjay N. Rakhade, Cristina Hilario-Gomez, Samantha S. Soldan, Evan C. Rosenberg, Jocelyn J. Lippman-Bell, Kaitlyn Folweiler, Marcus Handy
Publikováno v:
Neurobiology of Disease, Vol 116, Iss, Pp 120-130 (2018)
Neonatal seizures disrupt normal synaptic maturation and often lead to later-life epilepsy and cognitive deficits. During early life, the brain exhibits heightened synaptic plasticity, in part due to a developmental overabundance of CaV1.2 L-type vol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f152385b08349a5b0da899bd31e31e
https://pubmed.ncbi.nlm.nih.gov/29738885
https://pubmed.ncbi.nlm.nih.gov/29738885
Autor:
Orrin Devinsky, Peder S. Olofsson, Yvonne Naegelin, Matthias J. Koepp, Marc A. Dichter, Stéphane Auvin, Evan C. Rosenberg, Jacqueline A. French, Jong M. Rho, Federico Vigevano
Publikováno v:
Epilepsia, vol 58 Suppl 3, iss Suppl 3
Epilepsia, vol 58 Suppl 3, iss S3
Epilepsia, vol 58 Suppl 3, iss S3
In this exciting era, we are coming closer and closer to bringing an anti-inflammatory therapy to the clinic for the purpose of seizure prevention, modification, and/or suppression. At present, it is unclear what this approach might entail, and what
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8001d4b9c82ab19123f43a548b6e23
https://escholarship.org/uc/item/4c01f92z
https://escholarship.org/uc/item/4c01f92z
Publikováno v:
Epilepsy Research. 108:806-810
Tropomyosin-related kinase receptor B (TrkB) activation has been implicated in epileptogenesis. We investigated hippocampal levels of phosphorylated TrkB (p-TrkB) and potential antiepileptogenic actions of the tyrosine kinase inhibitor, lestaurtinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100a057af25b06cc9e823a7c564b1066
https://doi.org/10.1016/j.eplepsyres.2014.01.019
https://doi.org/10.1016/j.eplepsyres.2014.01.019
Publikováno v:
Epilepsybehavior : EB. 70
The isolation and identification of the discrete plant cannabinoids in marijuana revived interest in analyzing historical therapeutic claims made for cannabis in clinical case studies and anecdotes. In particular, sources as old as the 11th and 15th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907218696257a8fc60dab936e1e2b6d3
https://pubmed.ncbi.nlm.nih.gov/28190698
https://pubmed.ncbi.nlm.nih.gov/28190698
Publikováno v:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 12(4)
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports, accumulating animal model data, and mechanistic insights have raised interest in cannabis-based antiepileptic therapies. In this study, we review current understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34ea5c046b6005378dc74cba29afe9f
https://pubmed.ncbi.nlm.nih.gov/26282273
https://pubmed.ncbi.nlm.nih.gov/26282273