Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Evan C. Garrad"'
Autor:
Shikha Grover, Thao Pham, Anna Jones, Cristina Sinobas‐Pereira, Marina Villoch Diaz Maurino, Evan C. Garrad, Nyasha J. Makoni, Antanisha Parks, Ryan J. Domalewski, Gabriel Riggio, Hannah An, Kunhua Chen, Michael R. Nichols
Publikováno v:
Journal of Neurochemistry.
Autor:
Mohit B. Patel, Evan C. Garrad, Sergey L. Sedinkin, Saeedeh Negin, Michael R. Gokel, George W. Gokel, Shanheng Yin, Steven Korb
Publikováno v:
Chemical Science International Journal. :1-19
Aims: The aim of the study was to determine whether and to what extent any of a family of amphiphilic heptapeptide synthetic anion transporters (SATs) affected the growth or root morphology of Arabidopsis thaliana. Study Design: A. thaliana plants we
Publikováno v:
Biotechnology progressREFERENCES. 37(4)
The NLRP3 inflammasome is a key intracellular component of the innate immune response. It is a three-protein complex essential for the production of mature interleukin 1-β. The complex, which is comprised of three proteins, NLRP3, ASC, and pro-caspa
Autor:
Lisa K. Gouwens, David Osborn, Nathan T Zeller, Evan C. Garrad, Victoria A. Rogers, Mudar S Ismail, Fatima S. Amtashar, Michael R. Nichols, Nyasha J. Makoni
Publikováno v:
ACS Chemical Neuroscience. 9:1416-1425
Microvesicles (MVs) and exosomes comprise a class of cell-secreted particles termed extracellular vesicles (EVs). These cargo-holding vesicles mediate cell-to-cell communication and have recently been implicated in neurodegenerative diseases such as
Autor:
Evan C. Garrad, George W. Gokel, Joseph W. Meisel, Ariel Stavri, Saeedeh Negin, Mohit B. Patel, Michael R. Gokel, Zachary T. Cusumano
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:2864-2870
Hydraphiles are synthetic amphiphiles that form ion-conducting pores in liposomal membranes. These pores exhibit open-close behavior when studied by planar bilayer conductance techniques. In previous work, we showed that when co-administered with var
Autor:
Joseph W. Meisel, Evan C. Garrad, Saeedeh Negin, George W. Gokel, Michael R. Gokel, Mohit B. Patel
Publikováno v:
RSC advances. 9(4)
Antimicrobial resistance is a world-wide health care crisis. New antimicrobials must both exhibit potency and thwart the ability of bacteria to develop resistance to them. We report the use of synthetic ionophores as a new approach to developing non-
Autor:
Marie-Ève Tremblay, Colin K. Combs, Ann-Christin Wendeln, Nyasha J. Makoni, Mona Sohrabi, Jonas J. Neher, Marie-Kim St-Pierre, Lisa K. Gouwens, Evan C. Garrad, Michael R. Nichols
Publikováno v:
J Neurochem
Journal of neurochemistry 149(5), 562-581 (2019). doi:10.1111/jnc.14674
Journal of neurochemistry 149(5), 562-581 (2019). doi:10.1111/jnc.14674
This review discusses the profound connection between microglia, neuroinflammation, and Alzheimer’s disease (AD)(). Theories have been postulated, tested, and modified over several decades. The findings have further bolstered the belief that microg
Autor:
Ryan Cantwell, Evan C. Garrad, Michael R. Gokel, Michael J. Hayes, Joseph W. Meisel, Saeedeh Negin, Mohit B. Patel, George W. Gokel
Publikováno v:
Current Organic Chemistry. 19:2229-2236
Publikováno v:
Journal of the American Chemical Society. 138(33)
Nine bis(tryptophan) derivatives (BTs) and two control compounds were synthesized and tested for antimicrobial activity against two Escherichia coli strains and a Staphylococcus aureus strain. The effects of linker type, shape, and conformational rig