Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Evan B. Glass"'
Autor:
Evan B. Glass, Alyssa A. Hoover, Kennady K. Bullock, Matthew Z. Madden, Bradley I. Reinfeld, Whitney Harris, Dominique Parker, Demetra H. Hufnagel, Marta A. Crispens, Dineo Khabele, W. Kimryn Rathmell, Jeffrey C. Rathmell, Andrew J. Wilson, Todd D. Giorgio, Fiona E. Yull
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to provide increased benefits. One understudied approach is to target the l
Externí odkaz:
https://doaj.org/article/695878c019a54c44a19092e66e5e5079
Autor:
Alyssa A. Hoover, Demetra H. Hufnagel, Whitney Harris, Kennady Bullock, Evan B. Glass, Esther Liu, Whitney Barham, Marta A. Crispens, Dineo Khabele, Todd D. Giorgio, Andrew J. Wilson, Fiona E. Yull
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes represents an important
Externí odkaz:
https://doaj.org/article/1721307f4b964b83b11c876f207a8f61
Autor:
Evan B. Glass, Shirin Masjedi, Stephanie O. Dudzinski, Andrew J. Wilson, Craig L. Duvall, Fiona E. Yull, Todd D. Giorgio
Publikováno v:
ACS Omega, Vol 4, Iss 16, Pp 16756-16767 (2019)
Externí odkaz:
https://doaj.org/article/707777e550c74bc5b73e57113c426b70
Autor:
Sydney Ros Henriques, Ori Z. Chalom, Evan B. Glass, Sohini Roy, Abigail E. Manning, Benjamin C. Hacker, Marjan Rafat, Laura C. Kennedy, Fiona E. Yull, Young J. Kim, Todd D. Giorgio
Publikováno v:
Cancer Research. 83:2719-2719
Tumor-associated macrophages (TAMs) represent more than 50% of the immune cells in breast tumors, even in immune dysregulated, ‘cold’ tumors. TAMs that express an M2-like phenotype promote tumor growth and create an immunosuppressive tumor microe
Autor:
Whitney Barham, Fiona E. Yull, Demetra Hufnagel, Evan B. Glass, Whitney Harris, Dineo Khabele, Esther Liu, Alyssa Hoover, Marta A. Crispens, Andrew J. Wilson, Todd D. Giorgio, Kennady K. Bullock
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
BMC Cancer
BMC Cancer
Background New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes represents an important therapeut
Autor:
Evan B. Glass, Amy S. Major, Joseph A. Balsamo, Christopher P. Haycook, Todd D. Giorgio, Charles H. Williams, Charles C. Hong
Publikováno v:
International Journal of Nanomedicine. 15:1215-1228
Background Helper T cell activity is dysregulated in a number of diseases including those associated with rheumatic autoimmunity. Treatment options are limited and usually consist of systemic immune suppression, resulting in undesirable consequences
Autor:
Evan B. Glass, Alyssa A. Hoover, Kennady K. Bullock, Matthew Z. Madden, Bradley I. Reinfeld, Whitney Harris, Dominique Parker, Demetra H. Hufnagel, Marta A. Crispens, Dineo Khabele, W. Kimryn Rathmell, Jeffrey C. Rathmell, Andrew J. Wilson, Todd D. Giorgio, Fiona E. Yull
Publikováno v:
BMC cancer. 22(1)
Background Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to provide increased benefits. One understudied approach is to target the large popu
Autor:
Evan B. Glass, Sohini Roy, Marjan Rafat, Kennady K. Bullock, Abigail E. Manning, Christopher P. Haycook, Fiona E. Yull, Benjamin C. Hacker, Young J. Kim, Todd D. Giorgio, Bryan R. Dollinger
Publikováno v:
Immunology.
Autor:
Evan B. Glass, Allyson R. King, Isom B. Kelly, Alyssa M. Hasty, Prarthana Patil, Todd D. Giorgio, Bryan R. Dollinger, Fang Yu, Sean K. Bedingfield, Rachel E. Miles, Shrusti S. Patel, Meredith A. Jackson, Danielle D. Liu, Ella N. Hoogenboezem, Craig L. Duvall, Matthew A. Cottam
Publikováno v:
Biomaterials
In vivonanocarrier-associated toxicity is a significant and poorly understood hurdle to clinical translation of siRNA nanomedicines. In this work, we demonstrate that platelet activating factor (PAF), an inflammatory lipid mediator, plays a key role
Autor:
Alyssa R. Merkel, Todd D. Giorgio, Evan B. Glass, Dominique Parker, Alyssa Hoover, Fiona E. Yull, Julie A. Rhoades, Kennady K. Bullock, Richard Maynard, Andrew J. Wilson
Publikováno v:
Cancer Research. 81:2728-2728
Tumor associated macrophages (TAMs) often exist in high densities in breast tumors and are associated with adverse clinical outcomes. TAM repolarization as a strategy to shift the breast cancer microenvironment from immunosuppressive to immunostimula