Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling

Autor: Kreuzaler, Peter, Clarke, Matthew A., Brown, Elizabeth J., Wilson, Catherine H., Kortlever, Roderik M., Piterman, Nir, Littlewood, Trevor, Evan, Gerard I., Fisher, Jasmin

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2019 Oct . 116(44), 22399-22408.

Externí odkaz: https://www.jstor.org/stable/26859889

Requirement for the CD95 Receptor-Ligand Pathway in c-Myc-Induced Apoptosis

Autor: Hueber, Anne-Odile, Zörnig, Martin, Lyon, Debbie, Suda, Takashi, Nagata, Shigekazu, Evan, Gerard I.

Publikováno v: Science, 1997 Nov . 278(5341), 1305-1309.

Externí odkaz: https://www.jstor.org/stable/2894196

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Autor: Abbosh, Christopher, Frankell, Alexander M., Harrison, Thomas, Kisistok, Judit, Garnett, Aaron, Johnson, Laura, Veeriah, Selvaraju, Moreau, Mike, Chesh, Adrian, Chaunzwa, Tafadzwa L., Weiss, Jakob, Schroeder, Morgan R., Ward, Sophia, Grigoriadis, Kristiana, Shahpurwalla, Aamir, Litchfield, Kevin, Puttick, Clare, Biswas, Dhruva, Karasaki, Takahiro, Black, James R.M., Martínez-Ruiz, Carlos, Bakir, Maise Al, Pich, Oriol, Watkins, Thomas B.K., Lim, Emilia L., Huebner, Ariana, Moore, David A., Godin-Heymann, Nadia, L’Hernault, Anne, Bye, Hannah, Odell, Aaron, Roberts, Paula, Gomes, Fabio, Patel, Akshay J., Manzano, Elizabeth, Hiley, Crispin T., Carey, Nicolas, Riley, Joan, Cook, Daniel E., Hodgson, Darren, Stetson, Daniel, Barrett, J. Carl, Kortlever, Roderik M., Evan, Gerard I., Hackshaw, Allan, Daber, Robert D., Birkbak, Nicolai J.

Publikováno v: Abbosh, C, Frankell, A M, Harrison, T, Kisistok, J, Garnett, A, Johnson, L, Veeriah, S, Moreau, M, Chesh, A, Chaunzwa, T L, Weiss, J, Schroeder, M R, Ward, S, Grigoriadis, K, Shahpurwalla, A, Litchfield, K, Puttick, C, Biswas, D, Karasaki, T, Black, J R M, Martínez-Ruiz, C, Bakir, M A, Pich, O, Watkins, T B K, Lim, E L, Huebner, A, Moore, D A, Godin-Heymann, N, L’Hernault, A, Bye, H, Odell, A, Roberts, P, Gomes, F, Patel, A J, Manzano, E, Hiley, C T, Carey, N, Riley, J, Cook, D E, Hodgson, D, Stetson, D, Barrett, J C, Kortlever, R M, Evan, G I, Hackshaw, A, Daber, R D, Birkbak, N J & TRACERx Consortium 2023, ' Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA ', Nature, vol. 616, no. 7957, pp. 553-562 . https://doi.org/10.1038/s41586-023-05776-4

Circulating tumour DNA (ctDNA) can be used to detect and profile residual tumour cells persisting after curative intent therapy1. The study of large patient cohorts incorporating longitudinal plasma sampling and extended follow-up is required to dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::014e771c90ad8833f204964ed8e6acbe
https://pure.au.dk/portal/da/publications/tracking-early-lung-cancer-metastatic-dissemination-in-tracerx-using-ctdna(077da039-bbe4-4c24-8e7b-7e2452fef393).html

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Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy

Autor: Shchors, Ksenya, Persson, Anders I., Rostker, Fanya, Tihan, Tarik, Lyubynska, Natalya, Li, Nan, Swigart, Lamorna Brown, Berger, Mitchel S., Hanahan, Douglas, Weiss, William A., Evan, Gerard I.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2013 Apr . 110(16), 6254-6254.

Externí odkaz: https://www.jstor.org/stable/42590397