Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Evaldo dos Santos Monção Filho"'
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Akademický článek
Evaluation of antimutagenic and cytotoxic activity of skin secretion extract of Rhinella marina and Rhaebo guttatus (Anura, Bufonidae)
Autor: Angellica Fernandes de OLIVEIRA, Lindsey CASTOLDI, Gerardo Magela VIEIRA JUNIOR, Evaldo dos Santos MONÇÃO FILHO, Mariana Helena CHAVES, Domingos de Jesus RODRIGUES, Marina Mariko SUGUI
Publikováno v: Acta Amazonica, Vol 49, Iss 2, Pp 145-151 (2019)
ABSTRACT The skin secretion from toads of the Bufonidae family has great potential in the search for new active compounds to be used as drug candidates in treating some diseases, among them cancer. In this context, this study aimed to evaluate the cy
Externí odkaz: https://doaj.org/article/271b124b32d646128a31524b6f798577
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2
Akademický článek
Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs
Autor: Felipe Finger Banfi, Gabriela Camila Krombauer, Amanda Luisa da Fonseca, Renata Rachide Nunes, Silmara Nunes Andrade, Millena Alves de Rezende, Mariana Helena Chaves, Evaldo dos Santos Monção Filho, Alex Guterres Taranto, Domingos de Jesus Rodrigues, Gerardo Magela Vieira Júnior, Whocely Victor de Castro, Fernando de Pilla Varotti, Bruno Antonio Marinho Sanchez
Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases
Abstract Background: The resistance against antimalarial drugs represents a global challenge in the fight and control of malaria. The Brazilian biodiversity can be an important tool for research and development of new medicinal products. In this cont
Externí odkaz: https://doaj.org/article/7c28d3dbb91a41d7919a0a850f3ec02b
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3
Comparative study of composition of methanolic extracts of the paratoid gland secretions (PGS) of Rhinella jimi (cururu toad) from northeastern Brazil: Gender, seasonality and geographic occurrence
Autor: Elcio Daniel Sousa Barros, Evaldo dos Santos Monção Filho, Yara Polianna Fonseca Pio, Marcelo Rodrigues de Amorim, Roberto G.S. Berlinck, Rita de Cássia Moura, Mariluce Gonçalves Fonseca, Clécio Dantas, Ronaldo Cunha Coelho, Guilherme Ramos da Silva, Mariana Helena Chaves, Gerardo Magela Vieira Júnior
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Toads belonging to the Bufonidae family have a pair of paratoid glands that store highly toxic a biological secretion with varied chemical composition, that act as a chemical defense against microbial infections and predators. The paratoid gland secr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ca2dc7c411abe5a968560fae64453d
https://doi.org/10.1016/j.toxicon.2022.04.020
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5
Multi-response optimization of a solvent system for the extraction of antioxidants polyphenols from Jambolan fruit (Syzygium cumini (L.) Skeels)
Autor: Alessandro de Lima, José Augusto Gasparotto Sattler, Evaldo dos Santos Monção Filho, Ligia Bicudo de Almeida-Muradian, Bruno Quirino Araújo, Nadir do Nascimento Nogueira, Renato Pinto de Sousa, Antônia Maria das Graças Lopes Citó, Mariana de Morais Sousa, Márcio dos Santos Rocha
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The identification of bio-polyphenols from jambolan fruit is of great interest and requires extraction conditions that preserve their bioactivities. This study aimed to optimize a solvent system for the extraction of polyphenols from jambolan fruit p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a4cf877f0240eb59b4e240ff6eccea
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6
Avaliação da atividade antimutagênica e citotóxica da secreção cutânea de Rhinella marina e Rhaebo guttatus (Anura, Bufonidae)
Autor: Mariana Helena Chaves, Marina Mariko Sugui, Angellica Fernandes de Oliveira, Evaldo dos Santos Monção Filho, Gerardo Magela Vieira Júnior, Domingos de Jesus Rodrigues, Lindsey Castoldi
Publikováno v: Acta Amazonica v.49 n.2 2019
Acta Amazonica
Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron:INPA
Acta Amazonica, Volume: 49, Issue: 2, Pages: 145-151, Published: 06 MAY 2019
Acta Amazonica, Vol 49, Iss 2, Pp 145-151 (2019)
The skin secretion from toads of the Bufonidae family has great potential in the search for new active compounds to be used as drug candidates in treating some diseases, among them cancer. In this context, this study aimed to evaluate the cytotoxic a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff450b0912d7a64cc3f9963b78550cc
https://doi.org/10.1590/1809-4392201801751
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7
COMPOSIÇÃO QUÍMICA E ATIVIDADES FOTOPROTETORA E ANTIRADICALAR IN VITRO DOS GALHOS DE Platonia insignis (CLUSIACEAE)
Autor: Márcia Denise Alves Veras, Evaldo dos Santos Monção Filho, Rodrigo de Araujo Moreira, Mariana Helena Chaves, Andreia Giovana Aragão da Silva, Renato Pinto de Sousa, Sâmya Danielle Lima de Freitas
Publikováno v: Química Nova, Vol 44, Iss 8, Pp 954-962 (2021)
Química Nova v.44 n.8 2021
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 44, Issue: 8, Pages: 954-962, Published: 27 SEP 2021
CHEMICAL COMPOSITION AND PHOTOPROTECTIVE AND ANTIRADICAL ACTIVITIES OF THE BRANCHES OF Platonia insignis (CLUSIACEAE). The chemical study of the branches of Platonia insignis enabled the isolation of the biflavonoid morelloflavone and the identificat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a2c2ad59e09459037e5e05e06c4c4f
https://doi.org/10.21577/0100-4042.20170761
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8
Chemical Constituents and Cytotoxic Activity of Rhinella jimi (Anura: Bufonidae)
Autor: Evaldo dos Santos Monção Filho, Cláudia Pessoa, Mariluce Gonçalves Fonseca, Mariana Helena Chaves, Paulo Michel Pinheiro Ferreira, Yara P. F. Pio, Daisy Jereissati Barbosa Lima, Bruno Quirino Araújo, Gerardo Magela Vieira
Publikováno v: Journal of the Brazilian Chemical Society.
Rhinella jimi toads (Stevaux, 2002) belong to the Bufonidae family, are endemic in the Brazilian Northeast and are commonly found during rainy periods. In general, amphibians of this family have in their poisons different metabolites that show a dive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ba6847f6f5728acb5a613f5c8c9f757
https://doi.org/10.21577/0103-5053.20210009
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9
Cytotoxicity potential of chemical constituents isolated and derivatised from Rhinella marina venom
Autor: Evaldo dos Santos Monção Filho, Gerardo Magela Vieira Júnior, Paulo Michel Pinheiro Ferreira, Domingos de Jesus Rodrigues, Mariana Helena Chaves, Daisy Jereissati Barbosa Lima, Sarah Sant’Anna Maranhão, Cláudia Pessoa
Publikováno v: Toxicon : official journal of the International Society on Toxinology. 194
Chemical compounds from skin secretions from toads of Bufonidae family have been long-studied. In the search for new molecules with pharmacological action, the 3β-OH groups of bufadienolides are commonly derivatised using acetyl groups. This work de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f320d8e48a6af70ef813c512620512cd
https://pubmed.ncbi.nlm.nih.gov/33610630
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