Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Evald Rosengren"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 20:317-321
Publikováno v:
Acta Pharmacologica et Toxicologica. 54:346-351
We tried to find functional evidence for the existence of beta 1- and beta 2-adrenoceptors in the isolated guinea-pig lung parenchymal strip preparation, using potent and selective beta 1- and beta 2-adrenoceptor stimulation. To obtain potent beta 1-
Publikováno v:
Journal of Neurochemistry. 62:2030-2036
Model melanins, synthesized with different cysteinyldopamine/dopamine ratios in the incubates, were oxidized with KMnO4 and the resulting compounds were analyzed by HPLC. The ratios between a phaeomelanin-derived compound, thiazole-4,5-dicarboxylic a
Publikováno v:
Experimental Dermatology. 12:278-282
UVB light was used to induce an experimental inflammation in normal human skin in order to investigate its correlation with the activity of the newly described enzyme d-dopachrome tautomerase (DDT) in the fluid of experimental blisters. Macrophage mi
Publikováno v:
Inflammation Research. 45:513-518
In blood from the portal vein of anaesthetized rats the levels of histamine and putrescine were 2-3-fold lower compared to arterial blood. Putrescine concentration was increased severalfold and the difference between portal and arterial blood abolish
Autor:
Evald Rosengren, Christine N. Metz, Lars Jacobsson, Hans Rorsman, Richard Bucala, Gerd Odh, Pierre Åman
Publikováno v:
Europe PubMed Central
BACKGROUND: Recent studies of melanin biosynthesis have uncovered an unusual enzymatic activity which converts the non-naturally occurring D-isomer of 2-carboxy-2,3-dihydroindole-5,6-quinone (dopachrome) into 5,6-dihydroxyindole-2-carboxylic acid (DH
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1268:300-310
Melanin synthesis in the mouse involves the interaction of many pigmentation loci. Tyrosinase, the product of the albino (c) locus, catalyses the first step of the pathway. The brown (b) locus protein has significant homology to tyrosinase and contro
Publikováno v:
Pigment Cell Research. 7:305-310
The mouse b locus controls black/brown coat coloration. Its product, the b-protein or TRP-1, has significant homology to tyrosinase, and this has led to suggestions that the b-protein is itself a melanogenic enzyme. In order to investigate its functi
Publikováno v:
Journal of Investigative Dermatology. 100:S209-S213
The effects of systems generating active oxygen species (su-peroxide anion, hydrogen peroxide, hydroxyl radical) on tyrosinase have been studied in cultured human melanoma cells. Tyrosinase activity was determined by measuring the quantity of 5-S-L-c
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1097:152-160
The pigment of the human substantia nigra was isolated after extraction of lipids and proteins with 2% sodium cholate in 30% ethanol followed by 2% sodium dodecyl sulfate in 10% glycerol. The pigment was hydrolysed with HI or degraded by treatment wi