Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Evagelia S. Arsenou"'
Autor:
Evagelia S. Arsenou, George Pairas, Manolis A. Fousteris, Anna I. Koutsourea, Sotiris S. Nikolaropoulos, Athanasios A. Papageorgiou
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:5207-5215
The synthesis and the in vivo evaluation against leukemias P388 and L1210 of six new alkylating steroidal esters are described. The esteric derivatives incorporating the 17β-acetamido-B-lactamic steroidal skeleton exhibited increased antileukemic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a039c288dea57edf9c41831b264fc46
https://doi.org/10.1016/j.bmc.2008.03.015
https://doi.org/10.1016/j.bmc.2008.03.015
Autor:
Anna I, Koutsourea, Manolis A, Fousteris, Evagelia S, Arsenou, Athanasios, Papageorgiou, George N, Pairas, Sotiris S, Nikolaropoulos
Publikováno v:
In vivo (Athens, Greece). 22(3)
Recent structure-antileukemic activity studies showed that the steroidal part of complex molecules containing DNA alkylators does not play only the role of the "biological carrier". New such compounds designed to possess an allylic 7-ketone showed en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f459ed57a5c2d3846d43a8bdb08ef9e5
https://pubmed.ncbi.nlm.nih.gov/18610747
https://pubmed.ncbi.nlm.nih.gov/18610747
Autor:
Dionysios Mourelatos, Sotiris S. Nikolaropoulos, Athanasios A. Papageorgiou, Manolis A. Fousteris, Anna I. Koutsourea, Evagelia S. Arsenou
Publikováno v:
Anti-cancer drugs. 18(9)
This study was designed as a rational continuation of our research regarding the functional requirements essential for the antileukemic activity of compounds comprising an alkylating moiety and a modified steroid. The steroidal esteric derivatives of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece1aebec8ba83988557c5ceff3e58af
https://pubmed.ncbi.nlm.nih.gov/17704649
https://pubmed.ncbi.nlm.nih.gov/17704649
Autor:
Sotiris S. Nikolaropoulos, Manolis A. Fousteris, Dionysios Mourelatos, Athanasios A. Papageorgiou, Anna I. Koutsourea, Evagelia S. Arsenou
Publikováno v:
Anti-cancer drugs. 16(10)
We have studied the effect of modification of the B-steroidal ring to lactamic on the anti-leukemic potency of D-modified and D-non-modified steroidal esters of chlorambucil's active metabolite. The compounds synthesized were studied against leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673f773e3d7c6bc23b9ef2f3e01d47ea
https://pubmed.ncbi.nlm.nih.gov/16222149
https://pubmed.ncbi.nlm.nih.gov/16222149
Autor:
Manolis A, Fousteris, Anna I, Koutsourea, Evagelia S, Arsenou, Athanasios, Papageorgiou, Dionisis, Mourelato, Sotiris S, Nikolaropoulos
Publikováno v:
Anticancer research. 22(4)
The increase of the damaging effects on specific DNA sequences and the reduction of the subsequent toxicity of nitrogen mustards has been achieved by their chemical conjugation with modified steroids through an esteric bond. In an attempt to study th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e83ddc8d76501a192cfc3d38f97cea07
https://pubmed.ncbi.nlm.nih.gov/12174917
https://pubmed.ncbi.nlm.nih.gov/12174917