Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eva-Maria Zebedin"'
Autor:
Eva Maria Putz, Dagmar Gotthardt, Gregor Hoermann, Agnes Csiszar, Silvia Wirth, Angelika Berger, Elisabeth Straka, Doris Rigler, Barbara Wallner, Amanda M. Jamieson, Winfried F. Pickl, Eva Maria Zebedin-Brandl, Mathias Müller, Thomas Decker, Veronika Sexl
Publikováno v:
Cell Reports, Vol 4, Iss 3, Pp 437-444 (2013)
The transcription factor STAT1 is important in natural killer (NK) cells, which provide immediate defense against tumor and virally infected cells. We show that mutation of a single phosphorylation site (Stat1-S727A) enhances NK cell cytotoxicity aga
Externí odkaz:
https://doaj.org/article/5dbfdc32240242eeb0c34a9291efed38
Autor:
Johannes Pleiner-Duxneuner, Jörg Striessnig, Romuald Bellmann, Michael Pohl, Thomas Griesbacher, Martin Brunner, Markus Zeitlinger, Alexandra Koschak, Eva Maria Zebedin-Brandl
Publikováno v:
Intrinsic Activity. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::068abc27f377f495162d2248a47d2382
https://doi.org/10.25006/ia.9.1-pr1
https://doi.org/10.25006/ia.9.1-pr1
Autor:
Spiros Vamvakas, Caridad Pontes, Guido Rasi, Sonia Garcia, Giovanni Tafuri, Elangovan Gajraj, Frank Pétavy, Inês Lucas, Eva-Maria Zebedin-Brandl, Andrea Molina, Mercè Obach, Anne d'Andon, Niklas Hedberg, Pierluigi Russo, Marco Petschulies, Hannah Bruehl, Steve Estevão, Jane Moseley, Marco Massari, Anja Schiel, Leeza Osipenko, Marc Van de Casteele
Publikováno v:
British Journal of Clinical Pharmacology. 84:1013-1019
Aims The parallel regulatory–health technology assessment scientific advice (PSA) procedure allows manufacturers to receive simultaneous feedback from both EU regulators and health technology assessment (HTA) bodies on development plans for new med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab737af17a45373d25398987e4346be0
https://doi.org/10.1111/bcp.13524
https://doi.org/10.1111/bcp.13524
Autor:
Thomas Griesbacher, Jörg Striessnig, Alexandra Koschak, Michael Pohl, Eva Maria Zebedin-Brandl, Romuald Bellmann, Markus Zeitlinger, Martin Brunner, Johannes Pleiner-Duxneuner
Publikováno v:
Intrinsic Activity. 9:p1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fb9c1acbec903ea386c631137f98456
https://doi.org/10.25006/ia.9.1-p1
https://doi.org/10.25006/ia.9.1-p1
Autor:
Jane Moseley, Antje Behring, Frank Pétavy, Mercè Obach, Niklas Hedberg, Guido Rasi, Leeza Osipenko, Arantxa Catalan, Eva‐Maria Zebedin, Pierluigi Russo, Marco Massari, Marc Van de Casteele, Spiros Vamvakas, Elangovan Gajraj, Margherita Pagnini, Giovanni Tafuri
Publikováno v:
British Journal of Clinical Pharmacology
BACKGROUND: In 2010, the European Medicines Agency (EMA) initiated a pilot project on parallel scientific advice with Health Technology Assessment bodies (HTABs) that allows manufacturers to receive simultaneous feedback from both the European Union
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cf2a1c2295f7f9c367a9b9de384308
https://lirias.kuleuven.be/handle/123456789/669469
https://lirias.kuleuven.be/handle/123456789/669469
Autor:
Eva Maria, Putz, Andrea, Majoros, Dagmar, Gotthardt, Michaela, Prchal-Murphy, Eva Maria, Zebedin-Brandl, Daniela Alexandra, Fux, Andreas, Schlattl, Robert D, Schreiber, Sebastian, Carotta, Mathias, Müller, Christopher, Gerner, Thomas, Decker, Veronika, Sexl
Publikováno v:
Oncoimmunology
STAT1 is an important regulator of NK cell maturation and cytotoxicity. Although the consequences of Stat1-deficiency have been described in detail the underlying molecular functions of STAT1 in NK cells are only partially understood. Here, we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2234ede2fab95cfceae40d4d9490e792
https://pubmed.ncbi.nlm.nih.gov/27757297
https://pubmed.ncbi.nlm.nih.gov/27757297
Autor:
Eva Eckelhart, Christian Schuster, Eva-Maria Zebedin, Eva Weisz, Winfried F. Pickl, Wolgang Warsch, Dagmar Stoiber, Roland P. Piekorz, Olivia Simma, Michael Freissmuth, Veronika Sexl
Publikováno v:
BMC Pharmacology. 7
The PI3Kδ isoform is a candidate drug target in leukemia. Here, we explored its role in Abelson-induced leukemia. Frank leukemia emerges if the tumor cells have managed to outwit the immune system. The absence of PI3Kδ affected both the tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3580017db9976c56bc751aa54d97293b
https://doi.org/10.1186/1471-2210-7-s2-a7
https://doi.org/10.1186/1471-2210-7-s2-a7
Autor:
Halyna Pankevych, Xaver Koenig, Michael Freissmuth, Karlheinz Hilber, Eva-Maria Zebedin, Miroslav Radenković, Hannes Todt
Publikováno v:
BMC Pharmacology. 7
Drug-induced prolongation of the QT interval has become a major safety concern during drug development. Duramycin, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. It becomes deposited in cellular membranes where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a980568e0676af019df41923c3b66d40
https://doi.org/10.1186/1471-2210-7-s2-a9
https://doi.org/10.1186/1471-2210-7-s2-a9
Autor:
Eva-Maria Zebedin, Gerwin Heller, S Zöchbauer, Erwin F. Wagner, Olivia Simma, Michael Freissmuth, Rene G. Ott, Marina Schorpp-Kistner, Eva Weisz, Veronika Sexl, Karoline Kollmann
Publikováno v:
Oncogene. 26(33)
Loss of JunB has been observed in human leukemia and lymphoma, but it remains unknown, whether this loss is relevant to disease progression. Here, we investigated the consequences of JunB deficiency using Abelson-induced B-lymphoid leukemia as a mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08c6f1c2f640c6e4c71b7f5766e3479
https://pubmed.ncbi.nlm.nih.gov/17297445
https://pubmed.ncbi.nlm.nih.gov/17297445
Publikováno v:
BMC Pharmacology
Background In Austria, 98% of the population is covered by (statutory) health insurance. The HVB (Main Association of Austrian Social Security Institutions) publishes the Reimbursement Code (EKO) for outpatient medicines, and if new medicines are sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a9952f9129ecaa19ff8492ea4435f5