Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eva-Maria Weis"'
Autor:
Eva‐Maria Weis, Patrycja Puchalska, Alisa B Nelson, Jacqueline Taylor, Iris Moll, Sana S Hasan, Matthias Dewenter, Marco Hagenmüller, Thomas Fleming, Gernot Poschet, Agnes Hotz‐Wagenblatt, Johannes Backs, Peter A Crawford, Andreas Fischer
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 4, Pp 1-18 (2022)
Abstract Blood vessel formation is dependent on metabolic adaption in endothelial cells. Glucose and fatty acids are essential substrates for ATP and biomass production; however, the metabolism of other substrates remains poorly understood. Ketone bo
Externí odkaz:
https://doaj.org/article/ef5eaa2a664147ecb470d7766f67d5df
Autor:
Debarpan Guhathakurta, Aneta Petrušková, Enes Yağız Akdaş, Bartomeu Perelló-Amorós, Renato Frischknecht, Daniela Anni, Eva-Maria Weiss, Martin Walter, Anna Fejtová
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Ketamine is clinically used fast-acting antidepressant. Its metabolite hydroxynorketamine (HNK) shows a robust antidepressant effect in animal studies. It is unclear, how these chemically distinct compounds converge on similar neuronal effec
Externí odkaz:
https://doaj.org/article/66faa68a7b524b26b3fbcd9a4bf739d5
Autor:
Peter P. Nawroth, Norbert Gretz, Tjeerd P. Sijmonsma, Johannes Backs, Gernot Poschet, Adam J. Rose, Rüdiger Hell, Eva-Maria Weis, Sven W. Sauer, Ralf H. Adams, Hermann-Joseph Gröne, Jacqueline Taylor, Stefanie E. Herberich, Iris Moll, Jürgen G. Okun, Stephan Herzig, Lorenz H. Lehmann, Markus Jabs, Giuseppina Federico, Roland M. Schmid, Hellmut G. Augustin, Andreas Fischer, Minhong Yan, Carolin Mogler
Publikováno v:
Circulation 137, 2592-2608 (2018)
Background: Nutrients are transported through endothelial cells before being metabolized in muscle cells. However, little is known about the regulation of endothelial transport processes. Notch signaling is a critical regulator of metabolism and angi
Autor:
Andreas Fischer, Eva-Maria Weis, M Gordian Adam, Fabian Tetzlaff, Joycelyn Wüstehube-Lausch, Ralph Klose, Chio Oka, Michael Ehrmann, Iris Moll
Publikováno v:
Oncogene. 37:4260-4272
The serine protease HTRA1 is involved in several vascular diseases and its expression is often deregulated in cancer. We aimed at identifying how HTRA1 in the vasculature affects tumor growth. Here we report that silencing of HTRA1 in cultured endoth
Autor:
Eva-Maria Weiss, Debarpan Guhathakurta, Aneta Petrušková, Verena Hundrup, Martin Zenker, Anna Fejtová
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
RASopathies are a group of genetic disorders caused by mutations in genes encoding components and regulators of the RAS/MAPK signaling pathway, resulting in overactivation of signaling. RASopathy patients exhibit distinctive facial features, cardiopa
Externí odkaz:
https://doaj.org/article/6614b79375604446a8d3f40b06280d1f
Autor:
Andreas Fischer, Thomas Korff, Juan Rodriguez-Vita, Fabian Tetzlaff, Ralph Klose, Chio Oka, Eva-Maria Weis, Iris Moll, Alexander Prinz
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Vascular smooth muscle cell (VSMC) dysfunction is a hallmark of small vessel disease, a common cause of stroke and dementia. Two of the most frequently mutated genes in familial small vessel disease are HTRA1 and NOTCH3. The protease HTRA1 cleaves th
Autor:
Aneta Petrušková, Eva-Maria Weiss, Debarpan Guhathakurta, Enes Akdaş, Bartomeu Perelló, Renato Frischknecht, Tomáš Páleníček, Anna Fejtová
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S329- (2023)
Externí odkaz:
https://doaj.org/article/22d76328a0e0449aaa7cb78213c40072
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
The recent development of cellular imaging techniques and the application of genetically encoded sensors of neuronal activity led to significant methodological progress in neurobiological studies. These methods often result in complex and large data
Externí odkaz:
https://doaj.org/article/86c4aca52d24475f8d28b02be1b9eea5
Autor:
Christoph Seitz, Michael Rückert, Lisa Deloch, Eva-Maria Weiss, Sebastian Utz, Marika Izydor, Nina Ebel, Eberhard Schlücker, Rainer Fietkau, Udo S. Gaipl, Benjamin Frey
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Dendritic cell (DC)-based vaccines pulsed with high hydrostatic pressure (HHP)-inactivated tumor cells have been demonstrated to be a promising immunotherapy for solid tumors. We focused on sole injection of tumor cells that were inactivated by HHP a
Externí odkaz:
https://doaj.org/article/982bd7a12a1d4196a3f4da3bc9f6a0eb