Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eva-Maria Schnaeker"'
Autor:
Martin Steinhoff, Matthias F. Schneider, Volker Huck, Alexej Barg, Eva-Maria Schnaeker, Felix Kleinerüschkamp, Tobias Goerge, Stefan W. Schneider
Publikováno v:
Thrombosis and Haemostasis. 98:283-286
SummaryNeoplastic diseases are often associated with thromboembolic events,however the precise mechanism underlying this observation is a matter of ongoing investigation. It is known that matrixmetalloproteinase- 1 (MMP-1) canonically activates the t
Autor:
Tobias Goerge, Stefan W. Schneider, Christian Gorzelanny, Kai Thomas, Eva-Maria Schnaeker, Thomas A. Luger
Publikováno v:
Experimental Dermatology. 15:387-391
This study demonstrates an innovative application of atomic force microscopy (AFM). The combination of high-resolution AFM technology and tape stripping is presented as a tool for the structure analysis of human stratum corneum (SC) at a nanometer sc
Autor:
Eva-Maria Schnaeker, Rita Dreier, Marianne Wilhelmi, Stefan W. Schneider, Hans Oberleithner, Thomas Ludwig, Rainer Ossig
Publikováno v:
Cancer Research. 64:8924-8931
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that cleave and degrade a wide spectrum of extracellular matrix components. By enhancing turnover of extracellular matrix, MMP activity is also known to play a key role in tumor cell
Autor:
C Wunrau, Berno Dankbar, Katharina Freyth, Thomas Pap, Eva-Maria Schnaeker, Katja Neugebauer, Uwe Hansen, Doreen Wendholt, Noreen Pundt
Publikováno v:
Arthritis and rheumatism. 60(9)
Objective Synovial fibroblasts (SFs) contribute to several aspects of the pathogenesis of rheumatoid arthritis (RA) and have been implicated most prominently in the progressive destruction of articular cartilage. Targeting the invasive phenotype of R
Autor:
Tobias, Goerge, Felix, Kleinerüschkamp, Alexej, Barg, Eva-Maria, Schnaeker, Volker, Huck, Matthias F, Schneider, Martin, Steinhoff, Stefan W, Schneider
Publikováno v:
Thrombosis and haemostasis. 98(2)
Neoplastic diseases are often associated with thromboembolic events, however the precise mechanism underlying this observation is a matter of ongoing investigation. It is known that matrixmetalloproteinase-1 (MMP-1) canonically activates the thrombin
Publikováno v:
SPIE Proceedings.
A microfluidic system is presented that enables in-vitro investigations on tumor cells under conditions similar to those in a blood vessel. Microscopic test objects are immersed in a liquid that circulates in a closed-loop PDMS microchannel and that
Autor:
Matthias F. Schneider, Hans Oberleithner, Phillip Rogge, Volker Huck, Tobias Goerge, Stefan W. Schneider, Eva-Maria Schnaeker, Andre Niemeyer, Rainer Ossig
Publikováno v:
Journal of cellular physiology. 211(2)
Reperfusion after ischemic conditions induces massive endothelial cell (EC) activation, an initial step of reperfusion injury. Reperfusion is characterized by reoxygenation, realkalinization and a localized increase of inflammatory stimuli. In this s
Autor:
Christian Maaser, Alexej Barg, Stefan W. Schneider, Martin Steinhoff, Victoria M. Shpacovitch, Eva-Maria Schnaeker, Thomas A. Luger, Anke Rattenholl, Birgit Pöppelmann, Tobias Goerge
Publikováno v:
Cancer research. 66(15)
In the vascular system, circulating tumor cells interact with endothelial cells. Tumor-endothelial cross-talk transforms the intravascular milieu to a prothrombotic, proinflammatory, and cell-adhesive state called endothelial cell activation (ECA). I
Autor:
Eva-Maria, Schnaeker, Rainer, Ossig, Thomas, Ludwig, Rita, Dreier, Hans, Oberleithner, M, Wilhelmi, Stefan W, Schneider
Publikováno v:
Cancer research. 64(24)
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that cleave and degrade a wide spectrum of extracellular matrix components. By enhancing turnover of extracellular matrix, MMP activity is also known to play a key role in tumor cell
Autor:
Eva-Maria Schnaeker, Thomas A. Luger, Alexej Barg, Martin Steinhoff, Tobias Goerge, Stefan W. Schneider
Publikováno v:
Blood. 108:3945-3945
Extravasation of circulating tumor cells relies on efficient tumor-endothelial crosstalk. Only recently, we were able to demonstrate, that tumor-derived MMP-1 is capable of activating endothelial expressed PAR1 in the macro- and microvasculature (Can