Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eva-Maria Muth"'
Autor:
Verena Boschert, Maarten van Dinther, Stella Weidauer, Katharina van Pee, Eva-Maria Muth, Peter ten Dijke, Thomas D. Mueller
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/70ed4decf88046ff9d702b59d1e70283
Autor:
Maarten van Dinther, Juan Zhang, Stella E Weidauer, Verena Boschert, Eva-Maria Muth, Achim Knappik, David J J de Gorter, Puck B van Kasteren, Christian Frisch, Thomas D Mueller, Peter ten Dijke
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62295 (2013)
Sclerosteosis is a rare high bone mass disease that is caused by inactivating mutations in the SOST gene. Its gene product, Sclerostin, is a key negative regulator of bone formation and might therefore serve as a target for the anabolic treatment of
Externí odkaz:
https://doaj.org/article/f9a0fd8880214c629ade8f4eb736a565
Autor:
Verena Boschert, Maarten van Dinther, Stella Weidauer, Katharina van Pee, Eva-Maria Muth, Peter Ten Dijke, Thomas D Mueller
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81710 (2013)
The cystine-knot containing protein Sclerostin is an important negative regulator of bone growth and therefore represents a promising therapeutic target. It exerts its biological task by inhibiting the Wnt (wingless and int1) signaling pathway, which
Externí odkaz:
https://doaj.org/article/a228ee4bb24a4ece9007e486537ddd70
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 71:388-392
The secreted cystine-knot protein sclerostin was first identified from genetic screening of patients suffering from the rare bone-overgrowth diseases sclerosteosis and van Buchem disease. Sclerostin acts a negative regulator of bone growth through in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70553cc770e9f916ec53bc37eab6c65f
https://doi.org/10.1107/s2053230x1500360x
https://doi.org/10.1107/s2053230x1500360x
Autor:
Achim Knappik, Stella E. Weidauer, J. W. Back, Monika Beerbaum, Eva-Maria Muth, Thomas D. Mueller, Peter Schmieder, K. van Pee, Verena Boschert, Peter Timmerman, Christian Frisch
Publikováno v:
Open Biology, Vol 6, Iss 8 (2016)
Open biology, 6(8):160120
Open Biology
Open biology, 6(8):160120
Open Biology
The glycoprotein sclerostin has been identified as a negative regulator of bone growth. It exerts its function by interacting with the Wnt co-receptor LRP5/6, blocks the binding of Wnt factors and thereby inhibits Wnt signalling. Neutralizing anti-sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46acbedb0e10d4a8ab7bcc9b4a53bc57
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/17792
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/17792
Autor:
Verena Boschert, Maarten van Dinther, Stella Weidauer, Katharina van Pee, Eva-Maria Muth, Peter ten Dijke, Thomas D. Mueller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1 (2014)
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bb51ce955cbc50614a5b82de0bcdeb
http://europepmc.org/articles/PMC3882281
http://europepmc.org/articles/PMC3882281
Autor:
Eva-Maria Muth, Katharina van Pee, Thomas D. Mueller, Stella E. Weidauer, Peter ten Dijke, Verena Boschert, Maarten van Dinther
Publikováno v:
PLoS ONE
PLoS ONE, 8(11)
PLoS ONE, Vol 8, Iss 11, p e81710 (2013)
PLoS ONE; Vol 8
PLoS ONE, 8(11)
PLoS ONE, Vol 8, Iss 11, p e81710 (2013)
PLoS ONE; Vol 8
The cystine-knot containing protein Sclerostin is an important negative regulator of bone growth and therefore represents a promising therapeutic target. It exerts its biological task by inhibiting the Wnt (wingless and int1) signaling pathway, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec7a20adc3925369c0db85b3209e48f
https://pubmed.ncbi.nlm.nih.gov/24312339
https://pubmed.ncbi.nlm.nih.gov/24312339
Autor:
Thomas D. Mueller, Christian Frisch, Maarten van Dinther, Peter ten Dijke, Eva-Maria Muth, Verena Boschert, Juan Zhang, Achim Knappik, Stella E. Weidauer, Puck B. van Kasteren, David J. J. de Gorter
Publikováno v:
PLoS ONE
PLoS ONE, 8(4)
PLoS ONE, Vol 8, Iss 4, p e62295 (2013)
PLoS ONE, 8(4)
PLoS ONE, Vol 8, Iss 4, p e62295 (2013)
Sclerosteosis is a rare high bone mass disease that is caused by inactivating mutations in the SOST gene. Its gene product, Sclerostin, is a key negative regulator of bone formation and might therefore serve as a target for the anabolic treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb43fcf95cf450089b54f1eba6cb9523
https://pubmed.ncbi.nlm.nih.gov/23638027
https://pubmed.ncbi.nlm.nih.gov/23638027