Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Eva-Britt Samuelsson"'
Autor:
Homira Behbahani, Charlotte Forsell, Eva-Britt Samuelsson, Saara Tikka, Kirsten Coupland, Mahmod Panahi, Erik Sundström, Naeimeh Yousefi Mesri, Helena Karlström, Matti Viitanen, Bengt Winblad, Caroline Graff
Publikováno v:
Journal of Cellular and Molecular Medicine
Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a familial fatal progressive degenerative disorder. One of the pathological hallmarks of CADASIL is a dramatic reduction of vascular smooth muscle
Autor:
Erica Lana, Elisabet Åkesson, Charline Degavre, Evren Alici, Bengt Winblad, Homira Behbahani, Christina Unger Lithner, Eva-Britt Samuelsson, Mahbod Khanbolouki
Publikováno v:
Molecular Neurobiology. 54:874-887
Studies on the mechanisms of neuronal amyloid-β (Aβ) internalisation are crucial for understanding the neuropathological progression of Alzheimer's disease (AD). We here investigated how extracellular Aβ peptides are internalised and focused on th
Interplay between human microglia and neural stem/progenitor cells in an allogeneic co‐culture model
Autor:
Elisabet Åkesson, Jia Liu, Marianne Schultzberg, Eva-Britt Samuelsson, Mingqin Zhu, Erik Hjorth, Cinzia Calzarossa
Publikováno v:
Journal of Cellular and Molecular Medicine
Experimental neural cell therapies, including donor neural stem/progenitor cells (NPCs) have been reported to offer beneficial effects on the recovery after an injury and to counteract inflammatory and degenerative processes in the central nervous sy
Autor:
Erik Sundström, Eirikur Benedikz, Stefan Björklund, Elena Tortosa, Maria Eriksson, Jesús Avila, Helena Samuelsson, Eva-Britt Samuelsson
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Incorporation of the N-methyl-d-aspartate receptor (NMDAR) subunit NR3A into functional NMDARs results in reduced channel conductance and Ca2+ permeability. To further investigate the function of NR3A, we have set out to characterize its intracellula
Autor:
Ben A. Bahr, Eva-Britt Samuelsson, Scott Falci, Mia Emgård, Lena Holmberg, Åke Seiger, Erik Sundström
Publikováno v:
Brain Research. 1278:15-26
During the last decade, the interest in stem and progenitor cells, and their applications in spinal cord injuries have steadily increased. However, little is known about proliferation and cell death mechanisms in these cells after transplantation to
Autor:
Eirikur Benedikz, Maria Eriksson, Elisabet Åkesson, Nenad Bogdanovic, E. Chris Muly, Erik Sundström, Anna Nilsson, Eva-Britt Samuelsson
Publikováno v:
Nilsson, A, Eriksson, M, Muly, E C, Akesson, E, Samuelsson, E-B, Bogdanovic, N, Benedikz, E & Sundström, E 2007, ' Analysis of NR3A receptor subunits in human native NMDA receptors ', Brain Research, vol. 1186, pp. 102-12 . https://doi.org/10.1016/j.brainres.2007.09.008
NR3A, representing the third class of NMDA receptor subunits, was first studied in rats, demonstrating ubiquitous expression in the developing central nervous system (CNS), but in the adult mainly expressed in spinal cord and some forebrain nuclei. S
Autor:
Maria Eriksson, Elisabet Åkesson, Li-Li Mo, Helena Samuelsson, Anna Nilsson, Eirikur Benedikz, Erik Sundström, Eva-Britt Samuelsson
Publikováno v:
Eriksson, M, Nilsson, A, Samuelsson, H, Samuelsson, E-B, Mo, L, Akesson, E, Benedikz, E & Sundström, E 2007, ' On the role of NR3A in human NMDA receptors ', Physiology & Behavior, vol. 92, no. 1-2, pp. 54-9 . https://doi.org/10.1016/j.physbeh.2007.05.026
In the present paper we describe our on-going project investigating the functional roles of the N-methyl-D-aspartate (NMDA) receptor subunit NR3A. We find that NR3A mRNA is abundant both in embryonic and adult human brain, in contrast to the almost n
Autor:
Elisabet Åkesson, Eva-Britt Samuelsson, Åke Seiger, Jing-Hua Piao, Anders Kjaeldgaard, Lena Holmberg, Erik Sundström, Scott Falci
Publikováno v:
Physiology & Behavior. 92:60-66
There is heterogeneity in neural stem and progenitor cell characteristics depending on their species and regional origin. In search for potent in vitro-expanded human neural precursor cells and cell therapy methods to repair the injured human spinal
Publikováno v:
Journal of Neuroimmunology. 161:1-11
The ability to expand human neural precursor cells in vitro offers new possibilities for future cell therapies. However, concern over immunologically based rejection of in vitro-expanded human neural cells confounds their use as donor cells. Here, we
Autor:
Erik Sundström, Eva-Britt Samuelsson, Richard F. Cowburn, Åke Seiger, Fiona Flood, Janet A. Johnston, Birgitta Wiehager
Publikováno v:
Neurochemistry International. 44:487-496
Human neuroblastoma SH-SY5Y cells stably transfected with both wild-type and exon-9 deleted (deltaE9) presenilin constructs were used to study the role of the presenilin proteins during differentiation. Cells transfected with either wild-type or delt