Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Eva d'Hennezel"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The CD4+FOXP3+ regulatory T cell (Treg) subset is an indispensable mediator of immune tolerance. While high and stable expression of the transcription factor FOXP3 is considered a hallmark feature of Treg cells, our previous studies have demonstrated
Externí odkaz:
https://doaj.org/article/e9000418532a424aa46dc13f5f87a30d
Publikováno v:
mSystems, Vol 2, Iss 6 (2017)
ABSTRACT Cohabitation of microbial communities with the host enables the formation of a symbiotic relationship that maintains homeostasis in the gut and beyond. One prevailing model suggests that this relationship relies on the capacity of host cells
Externí odkaz:
https://doaj.org/article/31c2601de12a4e298c1a8fe332543565
Autor:
Jonathan Solomon, Simone Bonazzi, Eva d'Hennezel, Rohan Beckwith, Lei Xu, Aleem Fazal, Anna Magracheva, Radha Ramesh, Artiom Cernijenko, Brandon Antonakos, Hyo-eun Bhang, Roxana Garcia Caro, Jennifer Cobb, Elizabeth Ornelas, Xiaolei Ma, Charles Wartchow, Matt Clifton, Ry Forseth, Bethany Fortnam, Hongbo Lu, Alfredo Csibi, Jennifer Tullai, Seth Carbonneau, Noel Thomsen, Jay Larrow, Barbara Chie-Leon, Dominik Hainzl, Yi Gu, Darlene Lu, Matthew Meyer, Dylan Alexander, Jacqueline Kinyamu-Akunda, Catherine Sabatos-Peyton, Natalie Dales, Frederic Zecri, Rishi Jain, Janine Shulok, Y. Karen Wang, Karin Briner, Jeffrey Porter, John Tallarico, Jeffrey Engelman, Glenn Dranoff, Jay Bradner, Michael Visser
Growing malignant tumors must evade destruction by the immune system, a hurdle some malignancies overcome by attracting immune-suppressive regulatory T-cells (Tregs)1. The IKZF2 (Helios) transcription factor plays a crucial role in maintaining functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e91b1b99fea2c930f908b107802a0e27
https://doi.org/10.21203/rs.3.rs-1531006/v1
https://doi.org/10.21203/rs.3.rs-1531006/v1
Autor:
Simone Bonazzi, Eva d’Hennezel, Rohan E.J. Beckwith, Lei Xu, Aleem Fazal, Anna Magracheva, Radha Ramesh, Artiom Cernijenko, Brandon Antonakos, Hyo-eun C. Bhang, Roxana García Caro, Jennifer S. Cobb, Elizabeth Ornelas, Xiaolei Ma, Charles A. Wartchow, Matthew C. Clifton, Ry R. Forseth, Bethany Hughes Fortnam, Hongbo Lu, Alfredo Csibi, Jennifer Tullai, Seth Carbonneau, Noel M. Thomsen, Jay Larrow, Barbara Chie-Leon, Dominik Hainzl, Yi Gu, Darlene Lu, Matthew J. Meyer, Dylan Alexander, Jacqueline Kinyamu-Akunda, Catherine A. Sabatos-Peyton, Natalie A. Dales, Frédéric J. Zécri, Rishi K. Jain, Janine Shulok, Y. Karen Wang, Karin Briner, Jeffery A. Porter, John A. Tallarico, Jeffrey A. Engelman, Glenn Dranoff, James E. Bradner, Michael Visser, Jonathan M. Solomon
Publikováno v:
Cell Chemical Biology. 30:235-247.e12
Autor:
Meihang Li, Chao Sun, Constantin Polychronakos, Alan C. Peterson, Eva d'Hennezel, Natalija Popovic, Ciriaco A. Piccirillo, Hugues Beauchemin
Publikováno v:
Journal of Autoimmunity. 79:74-83
The C1858T single nucleotide polymorphism (SNP) in PTPN22 (protein tyrosine phosphatase nonreceptor 22) leads to the 620 Arg to Trp polymorphism in its encoded human protein LYP. This allelic variant is associated with multiple autoimmune diseases, i
Autor:
Mikael Knip, Suvi M. Virtanen, Hera Vlamakis, Susanne J. Szabo, Jorma Ilonen, Natalya Dorshakova, Moran Yassour, Curtis Huttenhower, Thomas W. Cullen, Timothy D. Arthur, Heli Siljander, Tommi Vatanen, Vallo Tillmann, Eva d'Hennezel, Jeffrey A. Porter, Aleksandr Peet, Raivo Kolde, Harri Lähdesmäki, Eric A. Franzosa, Ramnik J. Xavier, Sergei Mokurov, Anu Maaria Hämäläinen, Raivo Uibo, Aleksandar Kostic, Dirk Gevers
Publikováno v:
CELL. 165(4):842-853
According to the hygiene hypothesis, the increasing incidence of autoimmune diseases in western countries may be explained by changes in early microbial exposure, leading to altered immune maturation. We followed gut microbiome development from birth
Autor:
Bruce Mazer, Moshe Ben-Shoshan, Bin Li, Yasuhiro Nagai, Khalid Bin Dhuban, Steven Shao, Roman Istomine, Eva d'Hennezel, Ciriaco A. Piccirillo, Mark I. Greene, Wayne W. Hancock, Chiyoko Sekine, Fernando Alvarez, Yan Xiao, Hans D. Ochs, Troy R. Torgerson, Alan Berezov
Publikováno v:
Science Immunology. 2
CD4+FOXP3+ regulatory T (Treg) cells are critical mediators of immune tolerance, and their deficiency owing to FOXP3 mutations in immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX) patients results in severe autoimmunity. Dif
Autor:
Ciriaco A. Piccirillo, Hana Zouk, Constantin Polychronakos, X Du, Houria Ounissi-Benkalha, Eva d'Hennezel
Publikováno v:
Clinical and Experimental Immunology. 175:485-497
Summary The type 1 diabetes-associated 16p13 locus contains the CLEC16A gene. Its preferential immune cell expression suggests involvement in autoimmunity. Given its elevated expression in dendritic and B cells – known professional antigen-presenti
Autor:
Moshe Ben-Shoshan, Khalid Bin Dhuban, Christine McCusker, Bruce Mazer, Ann E. Clarke, Pierre Fiset, Ciriaco A. Piccirillo, Eva d'Hennezel
Publikováno v:
International Archives of Allergy and Immunology. 162:318-322
Background: While a central role for the T helper (Th) 1/Th2 axis in food allergy has been established, the Th17 response in food-allergic humans has not been addressed. Methods: Th17 responses in 18 peanut-allergic children, who were also allergic t
Autor:
Robert Linke, Reiko Kishikawa, Druckerei Stückle, Vojko Berce, Peter Korošec, Renata Baptista-dos-Reis, Bertine M. J. Flokstra-de Blok, Sayuri Nakayama, N. J. Goossens, Moshe Ben-Shoshan, Jones Meinir, Sanae Okada, Eva d'Hennezel, Wayne R. Thomas, Sara Casigliani Rabl, Barbara Bohle, Federico Pratesi, Hye Ryun Kang, Kyung-Up Min, M. Rosmilah, Abdullah Noormalin, Josiane S. Neves, Filomena Panza, Jae-Woo Jung, André C. Knulst, Woo-Jung Song, Terufumi Shimoda, Min-Gyu Kang, Yasushi Obase, Paola Migliorini, Bruce Mazer, Murad Shahnaz, Hiroshi Matsuda, Hae-Sim Park, Arip Masita, Jing Nan Liu, Maja Tomazin, Sang Heon Cho, Wataru Fujiwara, Satz Mengensatzproduktion, Tomoaki Iwanaga, Valdirene S. Muniz, Ans F.M. Lebens, Michael Könnecke, Manabu Shimojoh, Ilaria Puxeddu, Isabella Del Corso, Carla A.F.M. Bruijnzeel-Koomen, Debora Bartaloni, Ann E. Clarke, Maja Skerbinjek-Kavalar, Robert Böscke, Hye-Soo Yoo, Ronald van Ree, Khalid Bin Dhuban, Christine McCusker, Yoo Seob Shin, Rudolf Valenta, Tadashi Yoshida, Thuy-My Le, Mi-Ae Kim, Makoto Hattori, M.P. Gebhard, Barbara Wollenberg, Anthony E.J. Dubois, Ralph Pries, Karl Ludwig Bruchhage, Mohamed Jamaluddin, Mai Enomoto, Els van Hoffen, Hisashi Sugiyama, Ciriaco A. Piccirillo, Massimo Triggiani, Nina Čelesnik, Pierre Fiset, Matjaž Homšak, Valeria Rocchi, Mira Silar, Min Suk Yang, Mitja Košnik
Publikováno v:
International Archives of Allergy and Immunology. 162:I-IV