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pro vyhledávání: '"Eva Wulz"'
Synthesis and biological evaluation of new cytotoxic azanaphthoquinone pyrrolo-annelated derivatives
Autor:
Gilbert Müller, Eva Wulz, Helmut Spreitzer, Karem Shanab, Eckhard Günther, Babette Aicher, Peter Schmidt, Heike Knafl, Wolfgang Holzer, Eva Schirmer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3950-3952
A series of azanaphthoquinone pyrrolo-annelated derivatives attached to basic side chains have been synthesized. The antiproliferative activities of all compounds were evaluated on at least four different cell lines. The effects on cell cycle and int
Autor:
Rita Slanz, Wolfgang Holzer, Sigrid Lassnig, Karem Shanab, Babette Aicher, Eva Wulz, Gilbert Müller, Germana Fösleitner, Barbara Weissenbacher, Helmut Spreitzer, Eva Schirmer, Peter Schmidt, Eckhard Günther
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(10)
A series of 6-azanaphthoquinone pyrrolo-annelated derivatives carrying different basic side chains have been synthesized. The antiproliferative activities of all compounds were evaluated on at least four different cell lines with Mitoxantrone as refe
Autor:
Karem Shanab, Peter Schmidt, Gilbert Müller, Eva Wulz, Babette Aicher, Eckhard Günther, Wolfgang Holzer, Helmut Spreitzer, Nipawan Pongprom
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(22)
Two series of azanaphthoquinone annelated pyrrolo oximes have been synthesized. The antiproliferative activities of 10 compounds were evaluated on at least four different cell lines. One series of pyrrolo derivatives showed high cytotoxic activity. T