Výsledky vyhledávání - "Eva W Pedersen"

The molecular pathogenesis of acute promyelocytic leukaemia: implications for the clinical management of the disease

Autor: Eva W Pedersen, David Grimwade, Anita R. Mistry, Ellen Solomon

Publikováno v: Blood Reviews. 17:71-97

Acute promyelocytic leukaemia (APL) is characterised by chromosomal rearrangements of 17q21, leading to fusion of the gene encoding retinoic acid receptor alpha (RARalpha) to a number of alternative partner genes (X), the most frequent of which are P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9cce0645bd476b08a6c35727968452
https://doi.org/10.1016/s0268-960x(02)00075-9

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PML nuclear bodies in the pathogenesis of acute promyelocytic leukemia: active players or innocent bystanders?

Autor: David Grimwade, Michal Ramalho, Nicola J M Brown, Eva W Pedersen, Ellen Solomon, Eva Moravcsik

Publikováno v: Frontiers in Bioscience. :1684

The promyelocytic leukemia gene (PML) encodes a protein which localizes to PML-nuclear bodies (NBs), sub-nuclear multi-protein structures, which have been implicated in diverse biological functions such as apoptosis, cell proliferation and senescence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecad381f691222b3b3ea4b8fb02a9e8
https://doi.org/10.2741/3333

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