Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eva Vig"'
Autor:
Hyung Joo Kwon, Eva Vig, Kang-Yeol Yu, Mark G. Goebl, Maureen A. Harrington, Melissa Green, Yuanwen Liu, Jun Tian
Publikováno v:
Journal of Biological Chemistry. 276:7859-7866
The IL-1 receptor-associated kinase (IRAK/mPLK) is linked to the regulation of nuclear factor-kappaB (NF-kappaB)-dependent gene expression. Here we describe a novel binding partner of IRAK/mPLK that we term SIMPL (signaling molecule that associates w
Autor:
Harikrishna Nakshatri, Eva Vig, Wei Li, Feifei Chen, Yan Chen, Raman P. Nagarajan, Maureen A. Harrington
Publikováno v:
Biochemical Journal. 348:591-596
Activation of transforming growth factor-beta (TGF-beta) and activin receptors leads to phosphorylation of Sma- and Mad-related protein 2 (Smad2) and Smad3, which function as transcription factors to regulate gene expression. Smad7 is a regulatory pr
Publikováno v:
Biochemistry. 35:9746-9753
We have previously proposed a novel mechanism for the coupled regulation of glucocorticoid receptor (GR) and c-jun transcription in triamcinolone acetonide (TA)-treated AtT-20 cells. This involved transcriptional interference of AP-1 (Fos/Jun)-driven
Autor:
Erin Haag Breese, Eva Vig-Varga, Younghee Lee, Mark G. Goebl, Hyung-Joo Kwon, Maureen A. Harrington, Yong Luo
Publikováno v:
Molecular and cellular biology. 24(21)
A myriad of stimuli including proinflammatory cytokines, viruses, and chemical and mechanical insults activate a kinase complex composed of IkappaB kinase beta (IKK-beta), IKK-alpha, and IKK-gamma/N, leading to changes in NF-kappaB-dependent gene exp
Autor:
Maureen A. Harrington, Kang Yeol Yu, David A.M. Norman, Eva Vig, Hyung Joo Kwon, Mark G. Goebl
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(8)
Pellino is a Drosophila protein originally isolated in a two-hybrid screen for proteins interacting with the serine/threonine kinase, pelle. Although mammalian homologs have been identified in mouse and man, the function of pellino is as yet unknown.
Autor:
David B. Donner, Yuanwen Liu, Naofumi Mukaida, Melissa Green, Eva Vig, Mark G. Goebl, Maureen A. Harrington
Publikováno v:
The Journal of biological chemistry. 274(19)
The innate immune response is an important defense against pathogenic agents. A component of this response is the NF-kappaB-dependent activation of genes encoding inflammatory cytokines such as interleukin-8 (IL-8) and cell adhesion molecules like E-
Publikováno v:
DNA & Cell Biology; Dec2006, Vol. 25 Issue 12, p704-714, 11p, 3 Diagrams, 2 Charts, 2 Graphs
Autor:
Gitte Jakobsen
The world and its business environments are in a state of constant change. The reality today is that organizations and their leaders are faced with increasingly daunting demands for change and, unless they build organizations that can keep pace with
Autor:
Bhagavan Das
An examination of the similar truths in the religions of the world. Topic include Scientific Religion, Divine Will, the Nature of God, Evolution, Prayer, and the Sacraments.