Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Eva Tolosa"'
Autor:
Núria Ferrer-Bustins, Claire Yvon, Belén Martín, Vincent Leclerc, Jean-Charles Leblanc, Laura Corominas, Sara Sabaté, Eva Tolosa-Muñoz, Carme Chacón-Villanueva, Sara Bover-Cid, Sabrina Cadel-Six, Anna Jofré
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The presence of Salmonella in dry fermented sausages is source of recalls and outbreaks. The genomic diversity of 173 Salmonella isolates from the dry fermented sausage production chains (pig carcasses, pork, and sausages) from France and Sp
Externí odkaz:
https://doaj.org/article/785111475e924dc6aac6dfc507e04a31
Autor:
Stephan Menzel, Yinghui Duan, Julia Hambach, Birte Albrecht, Dorte Wendt-Cousin, Riekje Winzer, Eva Tolosa, Anne Rissiek, Andreas H. Guse, Friedrich Haag, Tim Magnus, Friedrich Koch-Nolte, Björn Rissiek
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
CD39 is the major enzyme controlling the levels of extracellular adenosine triphosphate (ATP) via the stepwise hydrolysis of ATP to adenosine diphosphate (ADP) and adenosine monophosphate (AMP). As extracellular ATP is a strong promoter of inflammati
Externí odkaz:
https://doaj.org/article/ede936c25e8b4acd80c5bcc8d2044e79
Autor:
Riekje Winzer, Du Hanh Nguyen, Felix Schoppmeier, Filippo Cortesi, Nicola Gagliani, Eva Tolosa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
An increase in the extracellular concentration of ATP as a consequence of cellular stress or cell death results in the activation of immune cells. To prevent inflammation, extracellular ATP is rapidly metabolized to adenosine, which deploys an anti-i
Externí odkaz:
https://doaj.org/article/5567e81fc7a0470690b8c4265e211e21
Autor:
Benjamin Grünhagel, Malte Borggrewe, Sven Hendrik Hagen, Susanne M. Ziegler, Florian Henseling, Laura Glau, Rebecca-Jo Thiele, Maria Pujantell, Varshi Sivayoganathan, Benedetta Padoan, Janna M. Claussen, Arne Düsedau, Jana Hennesen, Madeleine J. Bunders, Stefan Bonn, Eva Tolosa, Christian F. Krebs, Christoph Dorn, Marcus Altfeld
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108209- (2023)
Summary: Type I interferons (IFN-I) are important mediators of antiviral immunity and autoimmune diseases. Female plasmacytoid dendritic cells (pDCs) exert an elevated capacity to produce IFN-I upon toll-like receptor 7 (TLR7) activation compared to
Externí odkaz:
https://doaj.org/article/3e9659bff4ad40d09be5365c3478f73a
Autor:
Maximilian Wilmes, Carolina Pinto Espinoza, Peter Ludewig, Joschi Stabernack, Arthur Liesz, Annette Nicke, Mathias Gelderblom, Christian Gerloff, Simonetta Falzoni, Eva Tolosa, Francesco Di Virgilio, Björn Rissiek, Nikolaus Plesnilla, Friedrich Koch-Nolte, Tim Magnus
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Previous studies have demonstrated that purinergic receptors could be therapeutic targets to modulate the inflammatory response in multiple models of brain diseases. However, tools for the selective and efficient targeting of thes
Externí odkaz:
https://doaj.org/article/42a72dde94804cbaafa23cc1ebad1ef5
Autor:
Enja Schneider, Riekje Winzer, Anne Rissiek, Isabell Ricklefs, Catherine Meyer-Schwesinger, Franz L. Ricklefs, Andreas Bauche, Jochen Behrends, Rudolph Reimer, Santra Brenna, Hauke Wasielewski, Melchior Lauten, Björn Rissiek, Berta Puig, Filippo Cortesi, Tim Magnus, Ralf Fliegert, Christa E. Müller, Nicola Gagliani, Eva Tolosa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Ectonucleotidases associated to regulatory T cells are known modulators in the inflammatory environment. Here the authors describe CD8 T cell-derived extracellular vesicles bearing CD73 and suggest they function as an additional intrinsic modulator o
Externí odkaz:
https://doaj.org/article/423c6b103e9d4f51bf3e93a6880c1a59
Autor:
Julia Hambach, Tobias Stähler, Thomas Eden, Dorte Wendt, Natalie Tode, Friedrich Haag, Eva Tolosa, Marcus Altfeld, Anahita Fathi, Christine Dahlke, Marylyn M. Addo, Stephan Menzel, Friedrich Koch‐Nolte
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 3, Pp 905-917 (2021)
Abstract Background: Hamburg is a city state of approximately 1.9 Mio inhabitants in Northern Germany. Currently, the COVID‐19 epidemic that had largely subsided during last summer is resurging in Hamburg and in other parts of the world, underlinin
Externí odkaz:
https://doaj.org/article/b044e4bbe0284f9aa0510884b96b02c3
Autor:
Julie Pelletier, Jean Sévigny, Laura Schäkel, Salahuddin Mirza, Riekje Winzer, Vittoria Lopez, Riham Idris, Haneen Al-Hroub, Eva Tolosa, Christa E Müller
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background An important mechanism, by which cancer cells achieve immune escape, is the release of extracellular adenosine into their microenvironment. Adenosine activates adenosine A2A and A2B receptors on immune cells constituting one of the stronge
Externí odkaz:
https://doaj.org/article/8abf22ac4a1d4fadacc1d985d35a7a52
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11759 (2023)
The search for new and effective treatment targets for cancer immunotherapy is an ongoing challenge. Alongside the more established inhibitory immune checkpoints, a novel potential target is CD73. As one of the key enzymes in the purinergic signallin
Externí odkaz:
https://doaj.org/article/a39a38a347ba4b528027e637a876c2a5
Autor:
Anne Wisgalla, Caren Ramien, Mathias Streitz, Stephan Schlickeiser, Andreea-Roxana Lupu, Anke Diemert, Eva Tolosa, Petra C. Arck, Judith Bellmann-Strobl, Nadja Siebert, Christoph Heesen, Friedemann Paul, Manuel A. Friese, Carmen Infante-Duarte, Stefan M. Gold
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In multiple sclerosis (MS), relapse rate is decreased by 70-80% in the third trimester of pregnancy. However, the underlying mechanisms driving this effect are poorly understood. Evidence suggests that CD56bright NK cell frequencies increase during p
Externí odkaz:
https://doaj.org/article/5e4202b3faad46418f2d8e9500b9b902