Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Eva Tloušt'ová"'
Autor:
Marianne Fleuti, Tania Sanchez-Quirante, Lenka Poštová Slavětínská, Eva Tloušt'ová, Michal Tichý, Soňa Gurská, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
ACS Omega, Vol 9, Iss 18, Pp 20557-20570 (2024)
Externí odkaz:
https://doaj.org/article/9fd51b42b0dc460dae1b9022e978c82e
Autor:
Lucia Veselovská, Radek Pohl, Eva Tloušt′ová, Soňa Gurská, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
ACS Omega, Vol 5, Iss 40, Pp 26278-26286 (2020)
Externí odkaz:
https://doaj.org/article/da63e6d1e1a848d88919a30a79a6038a
Autor:
Jan Skácel, Stefan Djukic, Ondřej Baszczyňski, Filip Kalčic, Tadeáš Bílek, Karel Chalupský, Jaroslav Kozák, Alexandra Dvořáková, Eva Tloušt’ová, Zuzana Král’ová, Markéta Šmídková, Jan Voldřich, Michaela Rumlová, Petr Pachl, Jiří Brynda, Tereza Vučková, Milan Fábry, Jan Snášel, Iva Pichová, Pavlína Řezáčová, Helena Mertlíková-Kaiserová, Zlatko Janeba
Publikováno v:
Journal of Medicinal Chemistry. 66:6652-6681
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316a4b6200a65e0c79fc08dfbb8b4688
https://doi.org/10.1021/acs.jmedchem.2c02097
https://doi.org/10.1021/acs.jmedchem.2c02097
Autor:
Marcin Drąg, Jiří Brynda, Robin Kryštůfek, Jan Konvalinka, Eva Tloušt’ová, Martin Hradilek, Michael J. Boucher, Pavel Šácha, Justyna Grzymska, Pavlína Řezáčová, Miroslav Hájek, Jana Starková, Wioletta Rut, Charles S. Craik, Hiten D. Madhani, Pavel Majer
Publikováno v:
Journal of medicinal chemistry, vol 64, iss 10
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry
Cryptococcosis is an invasive infection that accounts for 15% of AIDS-related fatalities. Still, treating cryptococcosis remains a significant challenge due to the poor availability of effective antifungal therapies and emergence of drug resistance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a574ed99162f75480cfa117cbef17e66
https://doi.org/10.1021/acs.jmedchem.0c02177
https://doi.org/10.1021/acs.jmedchem.0c02177
Autor:
Anna Krajczyk, Martina Slapničková, Marian Hajduch, Pavla Perlíková, Nemanja Milisavljevic, Michal Hocek, Eva Doleželová, Eva Tloušt’ová, Lenka Poštová Slavětínská, Soňa Gurská, Petr Džubák, Alena Zíková
Publikováno v:
ACS infectious diseases. 7(4)
Human African Trypanosomiasis caused by Trypanosoma brucei species is one of the most damaging neglected tropical diseases. While the number of newly diagnosed cases per year is record low, there is still high interest in the development of new antit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b377d97f53ac230bddbfe49f01dde5
https://pubmed.ncbi.nlm.nih.gov/33769794
https://pubmed.ncbi.nlm.nih.gov/33769794
Autor:
Marian Hajduch, Lenka Poštová Slavětínská, Eva Tloušt’ová, Michal Tichý, Michal Hocek, Kateřina Bártová, Petr Pavlis, Marianne Fleuti, Soňa Gurská, Petr Džubák
Publikováno v:
The Journal of organic chemistry. 85(16)
A series of 8-substituted 1-methyl-1,4-dihydropyrazolo[3',4':4,5]pyrrolo[2,3-d]pyrimidine (methylpyrazolo-fused 7-deazapurine) ribonucleosides have been designed and synthesized. Two synthetic approaches to the key heterocyclic aglycon 7, (i) a six-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32942087404947942d9179e0cecca584
https://pubmed.ncbi.nlm.nih.gov/32692916
https://pubmed.ncbi.nlm.nih.gov/32692916
Autor:
Radek Pohl, Klára Hejtmánková, Tomáš Oždian, Marian Hajduch, Sabina Smoleń, Michal Hocek, Petr Džubák, Michal Tichý, Soňa Gurská, Eva Tloušt’ová, Barbora Lišková
Publikováno v:
Journal of Medicinal Chemistry. 60:2411-2424
Two isomeric series of new thieno-fused 7-deazapurine ribonucleosides (derived from 4-substituted thieno[2',3':4,5]pyrrolo[2,3-d]pyrimidines and thieno[3',2':4,5]pyrrolo[2,3-d]pyrimidines) were synthesized by a sequence involving Negishi coupling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec656c5b8894b76d2152073e5ba1be9
https://doi.org/10.1021/acs.jmedchem.6b01766
https://doi.org/10.1021/acs.jmedchem.6b01766
Autor:
Eva Kudova, Hana Chodounska, Pavla Hubalkova, Vojtech Vyklicky, Santosh Kumar Adla, Martin Svoboda, Markéta Šmídková, Kristina Holubova, Eva Tloušt’ová, Karel Vales, Milos Budesinsky, Michaela Nekardova, Barbora Krausova, Barbora Slavikova, Ladislav Vyklicky
Publikováno v:
Steroids. 117:52-61
Herein, we report a new class of amide-based inhibitors (1–4) of N-methyl- d -aspartate receptors (NMDARs) that were prepared as analogues of pregnanolone sulfate (PAS) and pregnanolone glutamate (PAG) – the steroidal neuroprotective NMDAR inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fb9f60fe69f9e6429095ccf18a8ed4
https://doi.org/10.1016/j.steroids.2016.08.010
https://doi.org/10.1016/j.steroids.2016.08.010
Autor:
Sabina Smoleń, Yiqian Wenren, Pavla Perlíková, Noor-Ul-Ain Khalid, Barbora Lišková, Blanka Klepetářová, Ivo Frydrych, Petr Džubák, Anna Tokarenko, Michal Tichý, Soňa Gurská, Marian Hajduch, Michal Hocek, Helena Mertlíková-Kaiserová, Pawel Znojek, Natálie Táborská, Eva Tloušt’ová, Lenka Poštová Slavětínská, Rebecca R. Laposa, Radek Pohl
Publikováno v:
Journal of medicinal chemistry. 62(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8314438b851e3b42a8f636cb2754cd
https://pubmed.ncbi.nlm.nih.gov/30281308
https://pubmed.ncbi.nlm.nih.gov/30281308
Autor:
Anna Tokarenko, Petr Džubák, Sabina Smoleń, Yiqian Wenren, Rebecca R. Laposa, Marian Hajduch, Noor-Ul-Ain Khalid, Soňa Gurská, Michal Tichý, Helena Mertlíková-Kaiserová, Pavla Perlíková, Barbora Lišková, Blanka Klepetářová, Eva Tloušt’ová, Ivo Frydrych, Natálie Táborská, Radek Pohl, Michal Hocek, Lenka Poštová Slavětínská, Pawel Znojek
Publikováno v:
Journal of Medicinal Chemistry
Three series of isomeric pyrrolo- and furo-fused 7-deazapurine ribonucleosides were synthesized and screened for cytostatic and antiviral activity. The synthesis was based on heterocyclizations of hetaryl-azidopyrimidines to form the tricyclic hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213346075a6778bef16bc04d7838a5c1
https://pubmed.ncbi.nlm.nih.gov/30681330
https://pubmed.ncbi.nlm.nih.gov/30681330