Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eva Situ"'
Autor:
David T. Beattie, M. Teresa Pulido-Rios, Fei Shen, Melissa Ho, Eva Situ, Pam R. Tsuruda, Patrick Brassil, Melanie Kleinschek, Sharath Hegde
Publikováno v:
Journal of Inflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background An unmet need remains for safe and effective treatments to induce and maintain remission in inflammatory bowel disease (IBD) patients. The Janus kinase (JAK) inhibitor, tofacitinib, has demonstrated robust efficacy in ulcerative c
Externí odkaz:
https://doaj.org/article/d1b63811139649dbba728e06e5dfa193
Autor:
Raj Bhandari, M. Teresa Pulido-Rios, David T Beattie, Reuben Sana, Brihad Abhyankar, Jonathan A. Leighton, Jacky Woo, Richard Graham, Eva Situ, Ravi Ganeshappa, Erik Sandvik, Melanie A. Kleinschek, Whitney Krey, David L. Boyle, Deanna D Nguyen, Julián Panés, William J. Sandborn, Patrick Brassil
Publikováno v:
Journal of Crohn's & Colitis
Journal of Crohn's & colitis, vol 14, iss 9
Journal of Crohn's & colitis, vol 14, iss 9
Background and Aims Oral systemic pan-Janus kinase [JAK] inhibition is effective for ulcerative colitis [UC] but is limited by toxicities. We describe preclinical to clinical translation of TD-1473—an oral gut-selective pan-JAK inhibitor—from in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5f63ccc3b54b28cf78acb55ba9f1eb
https://doi.org/10.1093/ecco-jcc/jjaa049
https://doi.org/10.1093/ecco-jcc/jjaa049
Autor:
Terrence F. Satterfield, Daniela Linzner, Poojan Suri, Samnang Tep, Rebeca M. Choy, Taru Gujral, Eva Situ, Yannan Xi, David Beattie, Sarah B. Noonberg, Sanjay Chandriani, Julie Ullman, Eric Green
Publikováno v:
Molecular Genetics and Metabolism. 138:107304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbdd7931ed5ad357a1829d200a10ae65
https://doi.org/10.1016/j.ymgme.2022.107304
https://doi.org/10.1016/j.ymgme.2022.107304
Autor:
Yannan Xi, Terrence F. Satterfield, Rebeca Choy, Tarunmeet Gujral, Eva Situ, Samnang Tep, Vivian Morton, Cecile Yu, Daniel Reiton, Baiwei Lin, Hanne Merritt, Pam Santiago, Bryan Espanol, Ryan A. Dick, Julie C. Ullman, Kevin T. Mellem, Sarah B. Noonberg, Eric M. Green, David J. Morgans, Sanjay J. Chandriani, David T. Beattie
Publikováno v:
Molecular Genetics and Metabolism. 135:S128
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4db8190e8c179bb281f026c5840c76
https://doi.org/10.1016/j.ymgme.2021.11.342
https://doi.org/10.1016/j.ymgme.2021.11.342
Autor:
Julie C. Ullman, Kevin T. Mellem, Yannan Xi, Terrence F. Satterfield, Tarunmeet Gujral, Rebeca Choy, Julian R. Homburger, Hanne Merritt, Daniel Reiton, Samnang Tep, Baiwei Lin, Cecile Yu, Eva Situ, Walter Won, Hannah Powers, Vyas Ramanan, Maarten Hoek, Robert Graham, Sanjay J. Chandriani, Christopher Sinz, Ryan A. Dick, Sarah B. Noonberg, David T. Beattie, David J. Morgans, null Jr, Eric M. Green
Publikováno v:
Molecular Genetics and Metabolism. 135:S122
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73295a112c6a5b30a62e86fb4a82cf5b
https://doi.org/10.1016/j.ymgme.2021.11.324
https://doi.org/10.1016/j.ymgme.2021.11.324
Autor:
Melissa Ho, Patrick Brassil, Sharath S. Hegde, M. Teresa Pulido-Rios, Fei Shen, David Beattie, Pam R. Tsuruda, Melanie A. Kleinschek, Eva Situ
Publikováno v:
Journal of Inflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Journal of Inflammation (London, England)
Journal of Inflammation (London, England)
Background An unmet need remains for safe and effective treatments to induce and maintain remission in inflammatory bowel disease (IBD) patients. The Janus kinase (JAK) inhibitor, tofacitinib, has demonstrated robust efficacy in ulcerative colitis pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec948a665fc9cb7ccfe7583523a1ce3
http://link.springer.com/article/10.1186/s12950-017-0175-2
http://link.springer.com/article/10.1186/s12950-017-0175-2
Autor:
Ashleigh Heinichen, Alexander McNamara, Elad Kaufman, Melanie A. Kleinschek, Eva Situ, Paul Fatheree, Wanju Lee, Christina G. Campbell
Publikováno v:
Airway pharmacology and treatment.
Janus kinase (JAK) inhibitors target a family of kinases that transduce cytokine mediated signals via the JAK / Signal Transducer and Activator of Transcription (STAT) pathway. JAK/STAT signaling cytokines contribute to asthma airway inflammation. TD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59620c58a42ffd0f448ed35ee9b599f7
https://doi.org/10.1183/13993003.congress-2019.oa4952
https://doi.org/10.1183/13993003.congress-2019.oa4952