SARIFA as a new histopathological biomarker is associated with adverse clinicopathological characteristics, tumor-promoting fatty-acid metabolism, and might predict a metastatic pattern in pT3a prostate cancer

Autor: Johanna S. Enke, Matthias Groß, Bianca Grosser, Eva Sipos, Julie Steinestel, Phillip Löhr, Johanna Waidhauser, Constantin Lapa, Bruno Märkl, Nic G. Reitsam

Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)

Abstract Background Recently, we introduced Stroma-AReactive-Invasion-Front-Areas (SARIFA) as a novel hematoxylin–eosin (H&E)-based histopathologic prognostic biomarker for various gastrointestinal cancers, closely related to lipid metabolism. To d

Externí odkaz: https://doaj.org/article/18fd73dfe9ba40d5951c91e04da8997a

Alterations in natural killer cells in colorectal cancer patients with Stroma AReactive Invasion Front Areas (SARIFA)

Autor: Nic G. Reitsam, Bruno Märkl, Sebastian Dintner, Eva Sipos, Przemyslaw Grochowski, Bianca Grosser, Florian Sommer, Stefan Eser, Pia Nerlinger, Frank Jordan, Andreas Rank, Phillip Löhr, Johanna Waidhauser

Publikováno v: Cancers
Volume 15
Issue 3
Pages: 994

Background: Recently, our group introduced Stroma AReactive Invasion Front Areas (SARIFA) as an independent prognostic predictor for a poorer outcome in colon cancer patients, which is probably based on immunologic alterations combined with a direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c30a8f029763ad48fd10e02344fd80
https://opus.bibliothek.uni-augsburg.de/opus4/files/102564/102564.pdf

First report from the German COVID-19 autopsy registry

Autor: Saskia von Stillfried, Roman David Bülow, Rainer Röhrig, Peter Boor, Jana Böcker, Jens Schmidt, Pauline Tholen, Raphael Majeed, Jan Wienströer, Joachim Weis, Juliane Bremer, Ruth Knüchel, Anna Breitbach, Claudio Cacchi, Benita Freeborn, Sophie Wucherpfennig, Oliver Spring, Georg Braun, Christoph Römmele, Bruno Märkl, Rainer Claus, Christine Dhillon, Tina Schaller, Eva Sipos, Klaus Hirschbühl, Michael Wittmann, Elisabeth Kling, Thomas Kröncke, Frank L. Heppner, Jenny Meinhardt, Helena Radbruch, Simon Streit, David Horst, Sefer Elezkurtaj, Alexander Quaas, Heike Göbel, Torsten Hansen, Ulf Titze, Johann Lorenzen, Thomas Reuter, Jaroslaw Woloszyn, Gustavo Baretton, Julia Hilsenbeck, Matthias Meinhardt, Jessica Pablik, Linna Sommer, Olaf Holotiuk, Meike Meinel, Nina Mahlke, Irene Esposito, Graziano Crudele, Maximilian Seidl, Kerstin U. Amann, Roland Coras, Arndt Hartmann, Philip Eichhorn, Florian Haller, Fabienne Lange, Kurt Werner Schmid, Marc Ingenwerth, Josefine Rawitzer, Dirk Theegarten, Christoph G. Birngruber, Peter Wild, Elise Gradhand, Kevin Smith, Martin Werner, Oliver Schilling, Till Acker, Stefan Gattenlöhner, Christine Stadelmann, Imke Metz, Jonas Franz, Lidia Stork, Carolina Thomas, Sabrina Zechel, Philipp Ströbel, Claudia Wickenhauser, Christine Fathke, Anja Harder, Benjamin Ondruschka, Eric Dietz, Carolin Edler, Antonia Fitzek, Daniela Fröb, Axel Heinemann, Fabian Heinrich, Anke Klein, Inga Kniep, Larissa Lohner, Dustin Möbius, Klaus Püschel, Julia Schädler, Ann-Sophie Schröder, Jan-Peter Sperhake, Martin Aepfelbacher, Nicole Fischer, Marc Lütgehetmann, Susanne Pfefferle, Markus Glatzel, Susanne Krasemann, Jakob Matschke, Danny Jonigk, Christopher Werlein, Peter Schirmacher, Lisa Maria Domke, Laura Hartmann, Isabel Madeleine Klein, Constantin Schwab, Christoph Röcken, Johannes Friemann, Dorothea Langer, Wilfried Roth, Stephanie Strobl, Martina Rudelius, Konrad Friedrich Stock, Wilko Weichert, Claire Delbridge, Atsuko Kasajima, Peer-Hendrik Kuhn, Julia Slotta-Huspenina, Gregor Weirich, Peter Barth, Eva Wardelmann, Katja Evert, Andreas Büttner, Johannes Manhart, Stefan Nigbur, Iris Bittmann, Falko Fend, Hans Bösmüller, Massimo Granai, Karin Klingel, Verena Warm, Konrad Steinestel, Vincent Gottfried Umathum, Andreas Rosenwald, Florian Kurz, Niklas Vogt

Publikováno v: The lancet / Regional health. Europe 15, 100330 (2022). doi:10.1016/j.lanepe.2022.100330

The lancet / Regional health. Europe 15, 100330 (2022). doi:10.1016/j.lanepe.2022.100330
Published by Elsevier, [Amsterdam]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad214196d1ae2e7ebcd368d363efb8f
https://pub.dzne.de/record/163685

The Concept of Stroma AReactive Invasion Front Areas (SARIFA) as a new prognostic biomarker for lipid-driven cancers holds true in pancreatic ductal adenocarcinoma.

Autor: Grochowski, Przemyslaw¹ (AUTHOR) przemyslaw.grochowski@uk-augsburg.de, Grosser, Bianca¹ (AUTHOR), Sommer, Florian² (AUTHOR), Probst, Andreas³ (AUTHOR), Waidhauser, Johanna⁴ (AUTHOR), Schenkirsch, Gerhard⁵ (AUTHOR), Reitsam, Nic G.¹ (AUTHOR), Märkl, Bruno¹ (AUTHOR)

Publikováno v: BMC Cancer. 6/26/2024, Vol. 24 Issue 1, p1-12. 12p.

Alterations in Natural Killer Cells in Colorectal Cancer Patients with Stroma AReactive Invasion Front Areas (SARIFA).

Autor: Reitsam, Nic G.¹ (AUTHOR) nic.reitsam@uka-science.de, Märkl, Bruno¹ (AUTHOR), Dintner, Sebastian¹ (AUTHOR), Sipos, Eva¹ (AUTHOR), Grochowski, Przemyslaw¹ (AUTHOR), Grosser, Bianca¹ (AUTHOR), Sommer, Florian² (AUTHOR), Eser, Stefan³ (AUTHOR), Nerlinger, Pia⁴ (AUTHOR), Jordan, Frank⁴ (AUTHOR), Rank, Andreas⁴ (AUTHOR), Löhr, Phillip⁴ (AUTHOR), Waidhauser, Johanna⁴ (AUTHOR)

Publikováno v: Cancers. Feb2023, Vol. 15 Issue 3, p994. 20p.