Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Eva Sevcsik"'
Autor:
Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, Francesca Nonateli, Timo Peters, Tassilo L.A. Wachsmann, Mercedes Hernandez-Rueda, Johannes B. Huppa, Gerhard J. Schütz, Eva Sevcsik, Beatriz Moreno, Fernando Pastor
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102198- (2024)
The CD3/T cell receptor (TCR) complex is responsible for antigen-specific pathogen recognition by T cells, and initiates the signaling cascade necessary for activation of effector functions. CD3 agonistic antibodies are commonly used to expand T lymp
Externí odkaz:
https://doaj.org/article/6c3ef753dfa94901b0ef2480454cb96e
Autor:
René Platzer, Benedikt K. Rossboth, Magdalena C. Schneider, Eva Sevcsik, Florian Baumgart, Hannes Stockinger, Gerhard J. Schütz, Johannes B. Huppa, Mario Brameshuber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Determining molecular clustering in Photoactivated Localization Microscopy (PALM) experiments requires knowledge of the blinking properties of the fluorophore to prevent overcounting artefacts. Here the authors develop an experimental and analytical
Externí odkaz:
https://doaj.org/article/d92f7a805d0a4aa697e8c1c2b9ffabca
Autor:
Marco Lindner, Aliz Tresztenyak, Gergö Fülöp, Wiebke Jahr, Adrian Prinz, Iris Prinz, Johann G. Danzl, Gerhard J. Schütz, Eva Sevcsik
Publikováno v:
Frontiers in Chemistry, Vol 6 (2019)
Protein micropatterning has become an important tool for many biomedical applications as well as in academic research. Current techniques that allow to reduce the feature size of patterns below 1 μm are, however, often costly and require sophisticat
Externí odkaz:
https://doaj.org/article/cb7163ac623f4b06ad676e3eafb9f066
Publikováno v:
Biomolecules, Vol 8, Iss 2, p 28 (2018)
The organization and dynamics of proteins and lipids in the plasma membrane, and their role in membrane functionality, have been subject of a long-lasting debate. Specifically, it is unclear to what extent membrane proteins are affected by their imme
Externí odkaz:
https://doaj.org/article/6447fd3f71b34a5dadd5124d9951ecc9
Publikováno v:
The Immune Synapse ISBN: 9781071631348
When T cells scan the surface of antigen-presenting cells (APCs), they can detect the presence of just a few antigenic peptide/MHC complexes (pMHCs), in some cases even a single agonist pMHC. These are typically vastly outnumbered by structurally sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c475c5973784849e0d4161ab2529eb
https://doi.org/10.1007/978-1-0716-3135-5_18
https://doi.org/10.1007/978-1-0716-3135-5_18
Autor:
Johannes B. Huppa, Elke Kurz, Magdalena C. Schneider, Eva Sevcsik, V. Muehlgrabner, Joschka Hellmeier, René Platzer, Gerhard J. Schuetz
Publikováno v:
ACS Nano
DNA origami structures provide flexible scaffolds for the organization of single biomolecules with nanometer precision. While they find increasing use for a variety of biological applications, the functionalization with proteins at defined stoichiome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211ebcba742034a8072d31ebe75dda60
https://doi.org/10.1021/acsnano.1c05411
https://doi.org/10.1021/acsnano.1c05411
Autor:
Sofia Moura, Ingrid Hartl, Atena Yasari, Veronika Brumovska, Yasmin Striedner, Marina Bishara, Theresa Mair, Thomas Ebner, Gerhard J. Schütz, Eva Sevcsik, Irene Tiemann-Boege
Delayed fatherhood results in a higher risk to inherit a new germline mutation that might result in a congenital disorder in the offspring. In particular, some FGFR3 mutations increase in frequency with age, but there are still a large number of unch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::875cf5f30ab43faf85a7764db57f7022
https://doi.org/10.1101/2022.07.31.502216
https://doi.org/10.1101/2022.07.31.502216
Autor:
Ingrid Hartl, Veronika Brumovska, Yasmin Striedner, Atena Yasari, Gerhard J. Schütz, Eva Sevcsik, Irene Tiemann-Boege
Publikováno v:
The Journal of biological chemistry.
Fibroblast growth factor receptors (FGFRs) initiate signal transduction via the RAS/MAPK pathway by their tyrosine-kinase activation known to determine cell-growth, tissue differentiation, and apoptosis. Recently, many missense mutations have been re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2e0e81a70aad84c2e079b302364b79
https://pubmed.ncbi.nlm.nih.gov/36581204
https://pubmed.ncbi.nlm.nih.gov/36581204
Autor:
Ingrid Hartl, Veronika Brumovska, Yasmin Striedner, Atena Yasari, Gerhard J. Schütz, Eva Sevcsik, Irene Tiemann-Boege
Publikováno v:
SSRN Electronic Journal.
Fibroblast growth factor receptors (FGFRs) initiate signal transduction via the RAS/MAPK pathway by their tyrosine-kinase activation known to determine cell-growth, tissue differentiation and apoptosis. Recently, many missense mutations have been rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6128cd5e685be1cc6c701c87dd40ea8d
https://doi.org/10.2139/ssrn.4080536
https://doi.org/10.2139/ssrn.4080536
Autor:
Florian Baumgart, Johannes B. Huppa, Tímea Váradi, Gerhard J. Schütz, Péter Nagy, Gyula Batta, René Platzer, Dominik Kiesenhofer, Tamás Kovács, Magdalena C. Schneider, Eva Sevcsik, Mario Brameshuber, János Szöllősi
Publikováno v:
Biophysical Journal
Dimerization or the formation of higher-order oligomers is required for the activation of ErbB receptor tyrosine kinases. The heregulin (HRG) receptor, ErbB3, must heterodimerize with other members of the family, preferentially ErbB2, to form a funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05d2d06e0c6c9a3e823e3daa3265723
https://doi.org/10.1016/j.bpj.2019.10.001
https://doi.org/10.1016/j.bpj.2019.10.001