Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Eva Serrano‐Candelas"'
Autor:
Domenico Gadaleta, Marina Garcia de Lomana, Eva Serrano-Candelas, Rita Ortega-Vallbona, Rafael Gozalbes, Alessandra Roncaglioni, Emilio Benfenati
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract The adverse outcome pathway (AOP) concept has gained attention as a way to explore the mechanism of chemical toxicity. In this study, quantitative structure–activity relationship (QSAR) models were developed to predict compound activity to
Externí odkaz:
https://doaj.org/article/f64a73920b77456f89cbc33ac1b0126b
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 15, Iss 1, Pp 854-866 (2024)
Quantitative structure–activity relationship (QSAR) models are routinely used to predict the properties and biological activity of chemicals to direct synthetic advances, perform massive screenings, and even to register new substances according to
Externí odkaz:
https://doaj.org/article/ccac76d232c84bf4b1f9ab6a4ada8336
Autor:
Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Inger-Lise Steffensen, Thomas Luechtefeld, Eva Serrano-Candelas, Marina Garcia de Lomana, Domenico Gadaleta, Hubert Dirven, Mathieu Vinken, Ramiro Jover
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116813- (2024)
Externí odkaz:
https://doaj.org/article/1a45ac20be3b45a6bda044ba4b82f287
Autor:
Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Inger-Lise Steffensen, Thomas Luechtefeld, Eva Serrano-Candelas, Marina Garcia de Lomana, Domenico Gadaleta, Hubert Dirven, Mathieu Vinken, Ramiro Jover
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116530- (2024)
Background: Serum transaminases, alkaline phosphatase and bilirubin are common parameters used for DILI diagnosis, classification, and prognosis. However, the relevance of clinical examination, histopathology and drug chemical properties have not bee
Externí odkaz:
https://doaj.org/article/20e9ebab41b6441c9e6177f4b5f66479
Autor:
Francesca Rispo, Giulia De Negri Atanasio, Ilaria Demori, Giosuè Costa, Emanuela Marchese, Simón Perera-del-Rosario, Eva Serrano-Candelas, Martina Palomino-Schätzlein, Elisabetta Perata, Federica Robino, Pier Francesco Ferrari, Sara Ferrando, Silvia Letasiova, Jan Markus, Matteo Zanotti-Russo, Elena Grasselli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Polyphenolic compounds constitute a diverse group of natural components commonly occurring in various plant species, known for their potential to exert both beneficial and detrimental effects. Additionally, these polyphenols have also been implicated
Externí odkaz:
https://doaj.org/article/7740777dee114e9ba29fc40ec5beb5b1
Autor:
Laureano E. Carpio, Marta Olivares, Alfonso Benítez-Paez, Eva Serrano-Candelas, Stephen J. Barigye, Yolanda Sanz, Rafael Gozalbes
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5744 (2024)
The role of the gut microbiota and its interplay with host metabolic health, particularly in the context of type 2 diabetes mellitus (T2DM) management, is garnering increasing attention. Dipeptidyl peptidase 4 (DPP4) inhibitors, commonly known as gli
Externí odkaz:
https://doaj.org/article/4a026f65921840ea9ead33f0fa477c8c
Autor:
Soroush Moasses Ghafary, Paula M. Soriano-Teruel, Shima Lotfollahzadeh, Mónica Sancho, Eva Serrano-Candelas, Fatemeh Karami, Stephen J. Barigye, Iván Fernández-Pérez, Rafael Gozalbes, Maryam Nikkhah, Mar Orzáez, Saman Hosseinkhani
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1651 (2022)
Inflammasomes are multiprotein complexes that represent critical elements of the inflammatory response. The dysregulation of the best-characterized complex, the NLRP3 inflammasome, has been linked to the pathogenesis of diseases such as multiple scle
Externí odkaz:
https://doaj.org/article/e6a1c1142a1f4ec899beb5196c854715
Autor:
Eva Serrano‐Candelas, Erola Ainsua‐Enrich, Arnau Navinés‐Ferrer, Paulo Rodrigues, Alfonso García‐Valverde, Sarah Bazzocco, Irati Macaya, Joaquín Arribas, César Serrano, Joan Sayós, Diego Arango, Margarita Martin
Publikováno v:
Molecular Oncology, Vol 12, Iss 8, Pp 1383-1397 (2018)
Gastrointestinal stromal tumors (GISTs) represent about 80% of the mesenchymal neoplasms of the gastrointestinal tract. Most GISTs contain oncogenic KIT (85%) or PDGFRA (5%) receptors. The kinase inhibitor imatinib mesylate is the preferential treatm
Externí odkaz:
https://doaj.org/article/44732c850c0545fbb2a5fcb190e1048f
Autor:
Arnau Navinés-Ferrer, Eva Serrano-Candelas, Alberto Lafuente, Rosa Muñoz-Cano, Margarita Martín, Gabriel Gastaminza
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/b429820b366b417482150785eae0e5c7
Autor:
Eva Serrano-Candelas, Rubén Martínez-Aranguren, Olga Vega, Gabriel Gastaminza, Joan Bartra, Maria Teresa Audicana, Jorge M. Núñez-Córdoba, Jaime Algorta, Antonio Valero, Margarita Martin, Marta Ferrer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Omalizumab (OmAb) is a humanized anti-IgE antibody approved for the treatment of chronic spontaneous urticaria (CSU). OmAb’s mechanism of action is known to include actions on free IgE and on pre-bound IgE. However, OmAb is equally and rap
Externí odkaz:
https://doaj.org/article/995bf92164984868a3e21c2d3ca0244e