Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Eva Schlede"'
2
Testing for skin sensitization according to the notification procedure for new chemicals: the Magnusson and Kligman test
Autor: Eva Schlede, Rosemarie Eppler
Publikováno v: Contact dermatitis. 32(1)
The notification procedure for new chemicals in the European Union (called the Chemicals Act in Germany) requires a skin sensitization test when the amount of a new chemical produced exceeds 100 kg/year. The preferred test is that of Magnusson and Kl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea928c6a89eddeec57f5ae01b43f365
https://pubmed.ncbi.nlm.nih.gov/7720363
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3
No differences in benzo(a)pyrene hydroxylase activity in the human immature placenta and in the human fetal liver from cigarette smoking and nonsmoking women
Autor: Eva Schlede, Horst Scholz
Publikováno v: Journal of Perinatal Medicine. 2:189-195
Cigarette smoking during pregnancy has been shown to increase the incidence of abortions, premature deliveries and lighter weight of the newborns. However, an explicit explanation for these findings is still lacking and until now it cannot be exclude
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b2551ce6df6d8c9104851b67bad0fa
https://doi.org/10.1515/jpme.1974.2.3.189
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4
Varying effect of phenobarbital on hepatic drug metabolism in rats of different ages
Autor: Eva Schlede
Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 282:311-315
The developmental pattern of benzo(a)pyrene hydroxylase and ethylmorphine N-demethylase from 8 days before birth up to 100 days of age in rat liver homogenate was investigated. These two drug metabolizing enzyme reactions exhibited their highest acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a119fe322ebb904ffefdd12d7eef9d
https://doi.org/10.1007/bf00501239
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5
Benzo(a)pyrene hydroxylase activity in the whole implantation site, decidua, placenta and fetal membranes of the rat
Autor: Eva Schlede, H. J. Merker
Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 282:59-73
Treatment of pregnant rats with 40 mg benzo(a)pyrene (BP) per kg body weight p.o. 24 h prior to sacrifice results in an induction of BP hydroxylase activity in the whole implantation site, the decidua, the placenta, and the fetal membranes. In contro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0953eeb1ff660f6b8f26f910879ec8
https://doi.org/10.1007/bf00647403
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6
Benzo(a)pyrene metabolism in hepatic microsomes from female da rats with a genetic sparteine oxidation deficiency
Autor: I. Roots, Eva Schlede
Publikováno v: Toxicology Letters. 29:5-10
The impact of the genetic hydroxylation deficiency described for several drugs such as sparteine, debrisoquine, and phenformin, has been studied with respect to benzo(a)pyrene (BP) metabolite formation. 14 C-BP (80 μM) was incubated with liver micro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62aafe8b9bea205c702680a834716cda
https://doi.org/10.1016/0378-4274(85)90192-4
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7
Decreased effect of phenobarbital treatment on microsomal drug metabolizing enzyme activity during gestation
Autor: Eva Schlede, R. Borowski
Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 281:341-355
Pregnant and nonpregnant rats were treated with 37.5 mg phenobarbital (PB) per kg body weight twice daily for 4 days. Pregnant rats were injected with PB from day 10 to day 13 and from day 17 to day 20 of gestation and were used for the experiments o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d71e49243769aedcba3077b4024658
https://doi.org/10.1007/bf00499430
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8
Effect of benzo( )pyrene treatment on the benzo( )pyrene hydroxylase activity in maternal liver, placenta, and fetus of the rat during day 13 to day 18 of gestation
Autor: H. J. Merker, Eva Schlede
Publikováno v: Naunyn-Schmiedeberg's archives of pharmacology. 272(1)
Pregnant rats were treated with an oral dose of 40.0 mg benzo(α) pyrene (BP) per kg body weight and were sacrificed 24 h later. Maternal liver, placenta, and fetus were assayed for BP-hydroxylase activity. The enzyme activity was measured from day 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cbc872bb43840f3bc83ff214530330
https://pubmed.ncbi.nlm.nih.gov/4257474
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