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pro vyhledávání: '"Eva Sarah Bartok"'
Autor:
Eva Sarah Bartok, Thomas Ostendorf, Thomas Zillinger, Katarzyna Andryka, Thais Marina Guimaraes, Saskia Schmitz, Samira Marx, Kübra Bayrak, Rebecca Linke, Sarah Salgert, Tatjana Grasser, Sonja Baersachs, Marc Hübner, Leon Soltesz, Matthias Kettwig, Maximilian Nastaly, Ingo Roehl, Marco Henneke, Winfried Barchet, Jutta Gärtner, Martin Schlee, Gunther Hartmann
Publikováno v:
The Journal of Immunology. 204:226.30-226.30
Human TLR8 is an essential sensor of bacterial RNA which induces proinflammatory and Th1 cytokines. Crystallography revealed that TLR8 binds both uridine and short single-stranded RNA, but the RNases that process the RNA are still unknown. Herein, we