Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Eva Santamaría"'
Autor:
Sergio Barace, Eva Santamaría, Stefany Infante, Sara Arcelus, Jesus De La Fuente, Enrique Goñi, Ibon Tamayo, Idoia Ochoa, Miguel Sogbe, Bruno Sangro, Mikel Hernaez, Matias A. Avila, Josepmaria Argemi
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 653 (2024)
Whole-tissue transcriptomic analyses have been helpful to characterize molecular subtypes of hepatocellular carcinoma (HCC). Metabolic subtypes of human HCC have been defined, yet whether these different metabolic classes are clinically relevant or d
Externí odkaz:
https://doaj.org/article/849503fa0ca248918b9f5150dce46864
Autor:
Laura M. Laiglesia, Xavier Escoté, Neira Sáinz, Elisa Felix-Soriano, Eva Santamaría, María Collantes, Marta Fernández-Galilea, Ignacio Colón-Mesa, Leyre Martínez-Fernández, Tania Quesada-López, Sergio Quesada-Vázquez, Carlos Rodríguez-Ortigosa, José M. Arbones-Mainar, Ángela M. Valverde, J Alfredo Martínez, Jesmond Dalli, Laura Herrero, Silvia Lorente-Cebrián, Francesc Villarroya, María J. Moreno-Aliaga
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101749- (2023)
Objective: Maresin 1 (MaR1) is a docosahexaenoic acid-derived proresolving lipid mediator with insulin-sensitizing and anti-steatosis properties. Here, we aim to unravel MaR1 actions on brown adipose tissue (BAT) activation and white adipose tissue (
Externí odkaz:
https://doaj.org/article/22820310ff864737969835f5345a7e5e
Autor:
María Páramo, Eva Santamaría, Miguel A. Idoate, Macarena Rodríguez-Fraile, Alberto Benito, Maria Collantes, Gemma Quincoces, Iván Peñuelas, Carmen Berasain, Josepmaria Argemi, Jorge Quiroga, Bruno Sangro, José I. Bilbao, Mercedes Iñarrairaegui
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Lobar selective internal radiation therapy (SIRT) is widely used to treat liver tumors inducing atrophy of the treated lobe and contralateral hypertrophy. The lack of animal model has precluded further investigations to improve this treatmen
Externí odkaz:
https://doaj.org/article/9b8adb35808e471683505cf5bacd215d
Autor:
Daniel Jericó, Karol M. Córdoba, Lei Jiang, Caroline Schmitt, María Morán, Ana Sampedro, Manuel Alegre, María Collantes, Eva Santamaría, Estíbaliz Alegre, Corinne Culerier, Ander Estella-Hermoso de Mendoza, Julen Oyarzabal, Miguel A. Martín, Iván Peñuelas, Matías A. Ávila, Laurent Gouya, Paolo G.V. Martini, Antonio Fontanellas
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 207-219 (2021)
Variegate porphyria (VP) results from haploinsufficiency of protoporphyrinogen oxidase (PPOX), the seventh enzyme in the heme synthesis pathway. There is no VP model that recapitulates the clinical manifestations of acute attacks. Combined administra
Externí odkaz:
https://doaj.org/article/f0e88f862dcd434c9fb48ea42beb448a
Autor:
Raquel Benedé‐Ubieto, Olga Estévez‐Vázquez, Feifei Guo, Chaobo Chen, Youvika Singh, Helder I. Nakaya, Manuel Gómez del Moral, Arantza Lamas‐Paz, Laura Morán, Nuria López‐Alcántara, Johanna Reissing, Tony Bruns, Matías A. Avila, Eva Santamaría, Marina S. Mazariegos, Marius Maximilian Woitok, Ute Haas, Kang Zheng, Ignacio Juárez, José Manuel Martín‐Villa, Iris Asensio, Javier Vaquero, Maria Isabel Peligros, Josepmaria Argemi, Ramón Bataller, Javier Ampuero, Manuel Romero Gómez, Christian Trautwein, Christian Liedtke, Rafael Bañares, Francisco Javier Cubero, Yulia A. Nevzorova
Publikováno v:
Hepatology Communications, Vol 5, Iss 6, Pp 1051-1068 (2021)
Individuals exhibiting an intermediate alcohol drinking pattern in conjunction with signs of metabolic risk present clinical features of both alcohol‐associated and metabolic‐associated fatty liver diseases. However, such combination remains an u
Externí odkaz:
https://doaj.org/article/0a79bde68d4940f383cf2ba5f8557b0d
Autor:
María Ancín, Ruth Sanz-Barrio, Eva Santamaría, Alicia Fernández-San Millán, Luis Larraya, Jon Veramendi, Inmaculada Farran
Publikováno v:
Plants, Vol 9, Iss 2, p 183 (2020)
Human cardiotrophin 1 (CT1), a cytokine with excellent therapeutic potential, was previously expressed in tobacco chloroplasts. However, the growth conditions required to reach the highest expression levels resulted in an impairment of its bioactivit
Externí odkaz:
https://doaj.org/article/0a8d3ee939ae41c089d8dd9071f067bd
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176091 (2017)
AIMS:To optimise a pharmacokinetic (PK) study design of rupatadine for 2-5 year olds by using a population PK model developed with data from a study in 6-11 year olds. The design optimisation was driven by the need to avoid children's discomfort in t
Externí odkaz:
https://doaj.org/article/58c11c05b42446b0a2444f7d4ed399bd
Autor:
Marco Gandarillas González, Luis Vásquez Rueda, Héctor Márquez Marmolejo, Eva Santamaría Gandarillas, Óscar Garaña Robles, Miguel Santibáñez Margüello
Publikováno v:
Medicina y Seguridad del Trabajo, Vol 60, Iss 234, Pp 64-89 (2014)
Objetivo: Realizar una evaluación del grado de satisfacción laboral y de apoyo social percibido en profesionales del Hospital Universitario Marqués de Valdecilla (HUMV). Trabajadores y método: Estudio transversal, descriptivo y analítico, en res
Externí odkaz:
https://doaj.org/article/4be4dc8dfb514d1fb830d4100efe4e60
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163020 (2016)
INTRODUCTION:Rupatadine is a marketed second generation antihistamine, with anti-PAF activity, indicated for symptomatic treatment of allergic rhinitis and urticaria. This study was conducted to evaluate the pharmacokinetics (PK), pharmacodynamics (P
Externí odkaz:
https://doaj.org/article/449169c79d604245831c95e8c59145d5
Autor:
Ignacio Melero, David Sancho, Alfonso R. Sánchez-Paulete, Maria Angela Aznar, Elixabet Bolaños, Susana Inoges, Arantza Azpilikueta, Michel Enamorado, Ana Rouzaut, Eva Santamaría, Iñaki Etxeberria, Saray Garasa, Sara Labiano, Alvaro Teijeira
T and NK lymphocytes express CD137 (4-1BB), a costimulatory receptor of the TNFR family whose function is exploitable for cancer immunotherapy. Mitochondria regulate the function and survival of T lymphocytes. Herein, we show that CD137 costimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b57df9beee8df1ccb4fa7ac07bcc732
https://doi.org/10.1158/2326-6066.c.6549254
https://doi.org/10.1158/2326-6066.c.6549254
