Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Eva S. Werstiuk"'
Autor:
Michel P. Rathbone, Christian Bau, Kathleen M. Pettifer, Patrizia Ballerini, Shucui Jiang, Eva S. Werstiuk, Iolanda D'Alimonte
Publikováno v:
Purinergic Signalling
Guanosine exerts neuroprotective effects in the central nervous system. Apoptosis, a morphological form of programmed cell death, is implicated in the pathophysiology of Parkinson's disease (PD). MPP(+), a dopaminergic neurotoxin, produces in vivo an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fbda47eb3d22bb8b5274a12de442dc
https://doi.org/10.1007/s11302-007-9073-z
https://doi.org/10.1007/s11302-007-9073-z
Publikováno v:
European Journal of Pharmacology. 560:17-22
We have reported that valproic acid upregulates melatonin MT1 receptor expression in rat C6 glioma cells. In addition to its anticonvulsant and mood stabilizing properties, valproic acid can also inhibit the growth of cancer cells. Since the melatoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bb5bb41d9ef5311e5a1bc392de310b
https://doi.org/10.1016/j.ejphar.2007.01.022
https://doi.org/10.1016/j.ejphar.2007.01.022
Autor:
James D. Ramsbottom, Robert Zielinski, Michel P. Rathbone, Caleb C. J. Zavitz, Iolanda D'Alimonte, Gemma Fischione, Ugo Traversa, Jian Wang, Patrizia Ballerini, Shucui Jiang, Silvia Romano, Eva S. Werstiuk, Amit Saraf
Publikováno v:
Purinergic Signalling
Wound healing is a complex sequence of cellular and molecular processes that involves multiple cell types and biochemical mediators. Several growth factors have been identified that regulate tissue repair, including the neurotrophin nerve growth fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516c8798b52697c8ce58a6bc7f2af6a8
http://europepmc.org/articles/PMC2096660
http://europepmc.org/articles/PMC2096660
Autor:
Michel P. Rathbone, James D. Ramsbottom, Francesco Caciagli, Eva Vertes, Sonya Kleywegt, Eva S. Werstiuk, Renata Ciccarelli, Christian Bau, Kathleen M. Pettifer
Publikováno v:
NeuroReport. 15:833-836
Apoptosis is implicated in the pathophysiology of Alzheimer's disease. Extracellular guanosine inhibits staurosporine-induced apoptosis in astrocytes. We examined whether guanosine protects SH-SY5Y human neuroblastoma cells against beta-amyloid(betaA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dc763ab93b6c91481b588792ba3258
https://doi.org/10.1097/00001756-200404090-00019
https://doi.org/10.1097/00001756-200404090-00019
Autor:
Pamela J. Middlemiss, Shucui Jiang, Ray Wickson, Michel P. Rathbone, Mohammad Imran Khan, Eva S. Werstiuk, Jian Wang
Publikováno v:
NeuroReport. 14:1301-1304
Transected dorsal root axons of adult rats can be induced to regenerate through the normally non-permissive environment of the dorsal root entry zone (DREZ) into the spinal cord by implanting enteric glia (EG) into the DREZ. We have now examined whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa32a9c8e0fa2436c4539be1e3082377
https://doi.org/10.1097/00001756-200307180-00003
https://doi.org/10.1097/00001756-200307180-00003
Autor:
Michel P. Rathbone, Eva S. Werstiuk, Renata Ciccarelli, Patrizia Di Iorio, Sonya Kleywegt, Candice E. Crocker, Ugo Traversa, Craig M. Andrew
Publikováno v:
Glia. 38:179-190
Astrocytes release adenine-based and guanine-based purines under physiological and, particularly, pathological conditions. Thus, the aim of this study was to determine if adenosine induced apoptosis in cultured rat astrocytes. Further, if guanosine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00c01efb4e00c18f45386a5b13d66a2
https://doi.org/10.1002/glia.10055
https://doi.org/10.1002/glia.10055
Autor:
Michel P. Rathbone, Eva S. Werstiuk, Renata Ciccarelli, Giulia Bombi, Ugo Traversa, Patrizia Di Iorio
Publikováno v:
British Journal of Pharmacology. 135:969-976
Extracellular guanosine has diverse effects on many cellular components of the central nervous system, some of which may be related to its uptake into cells and others to its ability to release adenine-based purines from cells. Yet other effects of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aa80c31a08253bce658c6f2c8fde5a7
https://doi.org/10.1038/sj.bjp.0704542
https://doi.org/10.1038/sj.bjp.0704542
Autor:
Feliciano Protasi, Michel P. Rathbone, Giorgio Fanò, Tiziana Pietrangelo, Eva S. Werstiuk, Paola Lorenzon, Stefania Fulle, Maria A. Mariggiò
Publikováno v:
Journal of Muscle Research and Cell Motility. 23:107-118
Receptor sites, specific for guanosine 5'-triphosphate (GTP) were characterised in myoblasts and myotubes of C2C12 mouse skeletal muscle cells, using binding experiments and measurements of intracellular Ca2+ concentration ([Ca2+]i). We identified tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3cec3f6db1b639852e483c916d9e061
https://doi.org/10.1023/a:1020288117082
https://doi.org/10.1023/a:1020288117082
Publikováno v:
Molecular and Cellular Biochemistry. 224:53-67
Knowledge of transcription and translation has advanced our understanding of cardiac diseases. Here, we present the hypothesis that the stability of mRNA mediated by the 3′-untranslated region (3′-UTR) plays a role in changing gene expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85e36da66088fa46a19d09c305a811b1
https://doi.org/10.1023/a:1011982932645
https://doi.org/10.1023/a:1011982932645
Autor:
Eva S Werstiuk, Robert MKW Lee
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 78:433-452
Functional β-adrenoceptors (β-AR) have been identified and characterized in blood vessels under in vivo conditions as well as in vascular smooth muscle cells (SMC) grown in culture. Agonist occupancy of β-AR activates adenylyl cyclase (AC) via the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd49f481f87d45d4442aad24306bb2e
https://doi.org/10.1139/y00-015
https://doi.org/10.1139/y00-015