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pro vyhledávání: '"Eva Ruff"'
Autor:
László Ötvös, Janos Sagi, Eva Ruff, Gyula Sági, Attila Szemzo, Katalin Ebinger, Anna Szabolcs
Publikováno v:
Tetrahedron Letters. 34:2191-2194
Properties of oligodeoxynucleotides essential for the antisense effect can be favourably modified by substitution of the heterocyclic base moiety. This is shown here for duplex stability by 5 alkyl, 5-(1-alkenyl) and 5-(1-alkynyl) substitution of the
Autor:
Eva Ruff, Jitka Štokrová, Alena Spánová, Jaroslav Kypr, László Ötvös, Michaela Vorlíčková, Janos Sagi
Publikováno v:
Biochemical and Biophysical Research Communications. 185:96-102
Three different concentrations of the antiherpetic agent 5-isopropyl-2'-deoxyuridine (ip5dU) were introduced into the synthetic DNA poly(dA-dT) to analyze resulting copolymers by electron microscopy, UV absorption and CD spectroscopy. The poly(dA-dT,