A collection of three integration-free iPSCs derived from old male and female healthy subjects

Autor: Eva Rodríguez-Traver, Eva Díaz-Guerra, César Rodríguez, Fabián Arenas, María Orera, Jaime Kulisevsky, Rosario Moratalla, Carlos Vicario

Publikováno v: Stem Cell Research, Vol 42, Iss , Pp - (2020)

Here, we present the characterization of three iPSC lines derived from dermal fibroblasts of old healthy subjects. Fibroblasts were reprogrammed using Sendai viral vectors encoding OCT4, SOX2, KLF4 and c-MYC. The iPSCs expressed endogenous pluripoten

Externí odkaz: https://doaj.org/article/e58cf9e4b1094feba1c6a7e26ec7c849

Generation of an integration-free iPSC line, ICCSICi006-A, derived from a male Alzheimer's disease patient carrying the PSEN1-G206D mutation

Autor: Eva Díaz-Guerra, Manuel A. Oria-Muriel, Elena P. Moreno-Jiménez, Itziar de Rojasb,, César Rodríguez, Eva Rodríguez-Traver, María Orera, Isabel Hernándezb,, Agustín Ruizb,, Carlos Vicario

Publikováno v: Stem Cell Research, Vol 40, Iss , Pp - (2019)

The familial form of Alzheimer's disease (FAD), which is caused by mutations in PRESENILIN 1 (PSEN1) and amyloid precursor protein (APP) genes, represents less than 5% of all AD cases and has an early-onset. We report the generation and characterizat

Externí odkaz: https://doaj.org/article/dbb39638ed824d1c901ae2f5464bc1fd

A collection of four integration-free iPSC lines derived from diagnosed sporadic Alzheimer's disease patients with different APOE alleles

Autor: Eva Díaz-Guerra, Elena P. Moreno-Jiménez, Itziar de Rojas, César Rodríguez, Eva Rodríguez-Traver, Esther Arribas-González, María Orera, Isabel Hernández, Agustín Ruiz, Carlos Vicario

Publikováno v: Stem Cell Research, Vol 39, Iss , Pp - (2019)

Genetic polymorphism of apolipoprotein E (APOE) confers differential susceptibility to late-onset Alzheimer's disease (LOAD). The ε3 allele of APOE, the most common isoform, does not represent a risk factor for LOAD. In contrast, the ε4 allele is t

Externí odkaz: https://doaj.org/article/8e2f1789e21148eebc02e9b45ee6d12f

A collection of three integration-free iPSCs derived from old male and female healthy subjects

Autor: Carlos Vicario, César Rodríguez, Eva Rodríguez-Traver, Eva Díaz-Guerra, Rosario Moratalla, Jaime Kulisevsky, María Orera, Fabián Arenas

Publikováno v: Stem Cell Research
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Digital.CSIC. Repositorio Institucional del CSIC
Stem Cell Research, Vol 42, Iss, Pp-(2020)

Here, we present the characterization of three iPSC lines derived from dermalfibroblasts of old healthy subjects. Fibroblasts were reprogrammed using Sendai viralvectors encoding OCT4, SOX2, KLF4 and c-MYC. The iPSCs expressed endogenous pluripotency

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce708982d1a5bb5280cd77021673f1d
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2127

A collection of four integration-free iPSC lines derived from diagnosed sporadic Alzheimer's disease patients with different APOE alleles

Autor: Carlos Vicario, César Rodríguez, Isabel Hernández, Eva Rodríguez-Traver, Itziar de Rojas, Elena P. Moreno-Jiménez, Eva Díaz-Guerra, Agustín Ruiz, Esther Arribas-González, María Orera

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Stem Cell Research, Vol 39, Iss, Pp-(2019)

Genetic polymorphism of apolipoprotein E (APOE) confers differential susceptibility to late-onset Alzheimer's disease (LOAD). The ε3 allele of APOE, the most common isoform, does not represent a risk factor for LOAD. In contrast, the ε4 allele is t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cc4eb1c2ca91a74928bd2fbd4c5428
https://pubmed.ncbi.nlm.nih.gov/31401456