Stereoselective Synthesis of Highly Substituted 1,3‐Dienes via 'à la carte' Multifunctionalization of Borylated Dendralenes

Autor: Eva Rivera-Chao, Martín Fañanás-Mastral

Publikováno v: Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Angewandte Chemie (International Ed. in English)

Despite the high relevance of 1,3‐dienes, stereoselective methods to access tetrasubstituted conjugated dienes are still scarce. We here report an efficient and modular approach that provides access to multifunctional tetrasubstituted 1,3‐dienes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4a12df1b0e357e5dbf6a7c5f88f2a4
https://doi.org/10.1002/ange.202104741

Electroaffinity Labeling: A New Platform for Chemoproteomic-based Target Identification

Autor: Yu Kawamata, Keun Ah Ryu, Gary Hermann, Alexander Sandahl, Julien Vantourout, Aleksandra Olow, La-Tonya Adams, Eva Rivera-Chao, Lee Roberts, Rob Oslund, Olugbeminiyi Fadeyi, phil baran

Target identification is a critical pillar within the drug discovery process that involves deconvoluting the protein target of a pharmacologically active small molecule ligand. While photoaffinity labeling strategies have become the benchmark for tar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b06e9180b77d091b52a2f118230574b3
https://doi.org/10.26434/chemrxiv-2022-s2m8f

Synthesis and Characterization of Bidentate (P^N)Gold(III) Fluoride Complexes: Reactivity Platforms for Reductive Elimination Studies

Autor: Alexandre Genoux, Michał Biedrzycki, Eva Rivera-Chao, Estíbaliz Merino, Anthony Linden, Cristina Nevado

Publikováno v: Angewandte Chemie (International ed. in English). 60(8)

A new family of cationic, bidentate (P^N)gold(III) fluoride complexes has been prepared and a detailed characterization of the gold‐fluoride bond has been carried out. Our results correlate with the observed reactivity of the fluoro ligand, which u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bab1f6fb934a3208747d93ad238e161
https://pubmed.ncbi.nlm.nih.gov/33015997

Synergistic Bimetallic Catalysis for Carboboration of Unsaturated Hydrocarbons

Autor: Eva Rivera-Chao, Martín Fañanás-Mastral, Laura Fra

Publikováno v: Synthesis. 50:3825-3832

Synergistic bimetallic catalysis has become a very efficient tool for the selective carboboration of unsaturated hydrocarbons. This synthetic approach is based on the use of a catalytically generated boron-substituted organocopper nucleophile in a cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e759a63f52eac4b6c33d6c06073e531
https://doi.org/10.1055/s-0037-1610434

Synergistic Copper/Palladium Catalysis for the Regio- and Stereoselective Synthesis of Borylated Skipped Dienes

Autor: Martín Fañanás-Mastral, Eva Rivera-Chao, Jaime Mateos

Publikováno v: Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname

A Cu/Pd-catalyzed allylboration of alkynes with allyl carbonates and bis(pinacolato)diboron to afford borylated skipped dienes is reported. Synergistic Cu and Pd catalysis enables this protocol to work for a wide array of alkynes and allyl carbonates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8b3bc95b4ea980a24628f15936b585
http://hdl.handle.net/10347/17015