The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes

Autor: Pablo Montañés-Agudo, Simona Aufiero, Eva N Schepers, Ingeborg van der Made, Lucia Cócera-Ortega, Auriane C Ernault, Stéphane Richard, Diederik W D Kuster, Vincent M Christoffels, Yigal M Pinto, Esther E Creemers

Publikováno v: Cardiovascular research, 119(5), 1161-1174. Oxford University Press
Montañés-Agudo, P, Aufiero, S, Schepers, E N, van der Made, I, Cócera-Ortega, L, Ernault, A C, Richard, S, Kuster, D W D, Christoffels, V M, Pinto, Y M & Creemers, E E 2023, ' The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes ', Cardiovascular Research, vol. 119, no. 5, pp. 1161-1174 . https://doi.org/10.1093/cvr/cvad007
Cardiovascular Research, 119(5), 1161-1174. Oxford University Press

Aims In the heart, splicing factors orchestrate the functional properties of cardiomyocytes by regulating the alternative splicing of multiple genes. Work in embryonic stem cells has shown that the splicing factor Quaking (QKI) regulates alternative

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https://pure.amc.nl/en/publications/the-rnabinding-protein-qki-governs-a-musclespecific-alternative-splicing-program-that-shapes-the-contractile-function-of-cardiomyocytes(48df7777-6df4-415c-856b-d4c9b3858e67).html