Výsledky vyhledávání - "Eva Munck‑Wikland"

Akademický článek

Tumour-draining lymph nodes in head and neck cancer are characterized by accumulation of CTLA-4 and PD-1 expressing Treg cells

Autor: Krzysztof Piersiala, Pedro Farrajota Neves da Silva, Vilma Lagebro, Aeneas Kolev, Magnus Starkhammar, Alexandra Elliot, Linda Marklund, Eva Munck-Wikland, Gregori Margolin, Susanna Kumlien Georén, Lars-Olaf Cardell

Publikováno v: Translational Oncology, Vol 23, Iss , Pp 101469- (2022)

Introduction: High Tregs infiltration within the tumour microenvironment (TME) of various cancers shows a positive correlation with poor prognosis. Despite the fact that tumour draining lymph nodes (TDLNs) are recognized as key organs playing a cruci

Externí odkaz: https://doaj.org/article/61f45db26b704df9b92cc0744d86906d

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Akademický článek

Tumour inflammation signature and expression of S100A12 and HLA class I improve survival in HPV-negative hypopharyngeal cancer

Autor: Michael Mints, David Landin, Anders Näsman, Leila Mirzaie, Ramona Gabriela Ursu, Mark Zupancic, Linda Marklund, Tina Dalianis, Eva Munck-Wikland, Torbjörn Ramqvist

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract Hypopharyngeal squamous cell carcinoma (HPSCC) has a very poor prognosis. Local surgery may increase survival, but is often avoided due to significant post-op co-morbidities. Since prognostic markers are lacking, the aim was to find predicti

Externí odkaz: https://doaj.org/article/7b38a5f9949a4258a73607c31b9902d9

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Akademický článek

Activation of T helper cells in sentinel node predicts poor prognosis in oral squamous cell carcinoma

Autor: Åsa Kågedal, Eric Hjalmarsson, Pedro Farrajota Neves da Silva, Krzysztof Piersiala, Susanna Kumlien Georén, Gregori Margolin, Eva Munck-Wikland, Ola Winqvist, Valtteri Häyry, Lars Olaf Cardell

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)

Abstract Recurrence in oral squamous cell carcinoma (OSCC) significantly reduces overall survival. Improved understanding of the host’s immune status in head and neck cancer may facilitate identification of patients at higher risk of recurrence and

Externí odkaz: https://doaj.org/article/fba114c3634743a6a7d2412014d261d1

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Akademický článek

Post-Treatment Neck Dissection of Tonsillar and Base of Tongue Squamous Cell Carcinoma in the Era of PET-CT, HPV, and p16

Autor: David Landin, Anders Näsman, Sara Jonmarker Jara, Lalle Hammarstedt-Nordenvall, Eva Munck-Wikland, Tina Dalianis, Linda Marklund

Publikováno v: Viruses, Vol 14, Iss 8, p 1693 (2022)

Human-papillomavirus (HPV)-positive tonsillar and base of tongue carcinomas (TSCC/BOTSCC) are rising in incidence and treatments with radiotherapy, chemoradiotherapy (RT/CRT), and neck dissections (NDs) have several side effects. Therefore, an improv

Externí odkaz: https://doaj.org/article/07765bfc5b3d4d2d8b8ac7f4cbed410e

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Akademický článek

Protein Expression in Tonsillar and Base of Tongue Cancer and in Relation to Human Papillomavirus (HPV) and Clinical Outcome

Autor: Torbjörn Ramqvist, Anders Näsman, Bo Franzén, Cinzia Bersani, Andrey Alexeyenko, Susanne Becker, Linnea Haeggblom, Aeneas Kolev, Tina Dalianis, Eva Munck-Wikland

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 4, p 978 (2018)

Human papillomavirus (HPV) is a major etiological factor for tonsillar and the base of tongue cancer (TSCC/BOTSCC). HPV-positive and HPV-negative TSCC/BOTSCC present major differences in mutations, mRNA expression and clinical outcome. Earlier protei

Externí odkaz: https://doaj.org/article/44449efb8a4348129049806e0891cc24

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Akademický článek

HLA class I and II expression in oropharyngeal squamous cell carcinoma in relation to tumor HPV status and clinical outcome.

Autor: Anders Näsman, Emilia Andersson, Linda Marklund, Nikolaos Tertipis, Lalle Hammarstedt-Nordenvall, Per Attner, Tommy Nyberg, Giuseppe V Masucci, Eva Munck-Wikland, Torbjörn Ramqvist, Tina Dalianis

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77025 (2013)

HPV-DNA positive (HPVDNA+) oropharyngeal squamous cell carcinoma (OSCC) has better clinical outcome than HPV-DNA negative (HPVDNA-) OSCC. Current treatment may be unnecessarily extensive for most HPV+ OSCC, but before de-escalation, additional marker

Externí odkaz: https://doaj.org/article/ebc1795793b94a3bb5277bc7796c94fd

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Akademický článek

Tumor infiltrating CD8+ and Foxp3+ lymphocytes correlate to clinical outcome and human papillomavirus (HPV) status in tonsillar cancer.

Autor: Anders Näsman, Mircea Romanitan, Cecilia Nordfors, Nathalie Grün, Hemming Johansson, Lalle Hammarstedt, Linda Marklund, Eva Munck-Wikland, Tina Dalianis, Torbjörn Ramqvist

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38711 (2012)

BACKGROUND: Human papillomavirus (HPV) is a causative factor for tonsillar squamous cell carcinoma (TSCC) and patients with HPV positive (HPV(+)) TSCC have a better clinical outcome than those with HPV negative (HPV(-)) TSCC. However, since not all p

Externí odkaz: https://doaj.org/article/d3e7dc3b295b484c8b75c1ef266136b8

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