Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eva Moravcsik"'
Autor:
Ellen Solomon, Eva W. Stratford, Scott C. Kogan, Edwige Voisset, Christopher J. Palgrave, Eva Moravcsik, David Grimwade, Robert Kerrin Hills, Amie Jaye, Paolo Salomoni
Publikováno v:
Voisset, E, Moravcsik, E, Stratford, E W, Jaye, A, Palgrave, C J, Hills, R K, Salomoni, P, Kogan, S C, Solomon, E & Grimwade, D 2018, ' Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice ', Blood, vol. 131, no. 6, pp. 636–648 . https://doi.org/10.1182/blood-2017-07-794784
Blood 131(6), 636-648 (2018). doi:10.1182/blood-2017-07-794784
Blood, vol 131, iss 6
Blood 131(6), 636-648 (2018). doi:10.1182/blood-2017-07-794784
Blood, vol 131, iss 6
A hallmark of acute promyelocytic leukemia (APL) is altered nuclear architecture, with disruption of promyelocytic leukemia (PML) nuclear bodies (NBs) mediated by the PML-retinoic acid receptor α (RARα) oncoprotein. To address whether this phenomen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af28ac757400333bffb6a725374d8160
https://kclpure.kcl.ac.uk/ws/files/128777181/Pml_nuclear_body_disruption_cooperates_in_APL_pathogenesis_and_impairs_DNA_damage_repair_pathways_in_mice.pdf
https://kclpure.kcl.ac.uk/ws/files/128777181/Pml_nuclear_body_disruption_cooperates_in_APL_pathogenesis_and_impairs_DNA_damage_repair_pathways_in_mice.pdf
Autor:
Sameena Iqbal, David Grimwade, Bryan D. Young, Floriana Manodoro, Jelena V. Jovanovic, Silvana Debernardi, Jun Wang, Tracy Chaplin, Farideh Miraki-Moud, John G. Gribben, Jacek Marzec, Eva Moravcsik, David Taussig
Publikováno v:
Blood. 123:2066-2074
Distinct patterns of DNA methylation characterize the epigenetic landscape of promyelocytic leukemia/retinoic acid receptor-α (PML-RARα)-associated acute promyelocytic leukemia (APL). We previously reported that the microRNAs (miRNAs) clustered on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7228b4bef0517aabf43eb40e314c7b66
https://doi.org/10.1182/blood-2012-12-469833
https://doi.org/10.1182/blood-2012-12-469833
Autor:
David Grimwade, Bernd B. Zeisig, Jo Morris, Edwige Voisset, Gordon Stamp, Paolo Salomoni, Robert Kerrin Hills, Emma Nye, Scott C. Kogan, Chris Palgrave, Melanie Joannides, Eva Moravcsik, Chi Wai Eric So, Ellen Solomon, Eva W. Stratford, Ruth M Densham
Publikováno v:
Blood, vol 122, iss 21
Acute promyelocytic leukemia (APL) is characterised by the t(15;17)(q22;q21) leading to fusion of PML to the gene encoding the myeloid transcription factor Retinoic Acid Receptor α (RARα). Chromosomal translocations such as the t(15;17) are conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed9a3b46dabd449df9d06a545dce551
https://escholarship.org/uc/item/9zm931zb
https://escholarship.org/uc/item/9zm931zb
Autor:
David Grimwade, Michal Ramalho, Nicola J M Brown, Eva W Pedersen, Ellen Solomon, Eva Moravcsik
Publikováno v:
Frontiers in Bioscience. :1684
The promyelocytic leukemia gene (PML) encodes a protein which localizes to PML-nuclear bodies (NBs), sub-nuclear multi-protein structures, which have been implicated in diverse biological functions such as apoptosis, cell proliferation and senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecad381f691222b3b3ea4b8fb02a9e8
https://doi.org/10.2741/3333
https://doi.org/10.2741/3333
Autor:
Katalin Solti, Wei-Li Kuan, Balázs Fórizs, Gergely Kustos, Judith Mihály, Zoltán Varga, Balázs Herberth, Éva Moravcsik, Róbert Kiss, Manuela Kárpáti, Anna Mikes, Yanyan Zhao, Tímea Imre, Jean-Christophe Rochet, Franklin Aigbirhio, Caroline H. Williams-Gray, Roger A. Barker, Gergely Tóth
Publikováno v:
Neurobiology of Disease, Vol 142, Iss , Pp 104971- (2020)
Externí odkaz:
https://doaj.org/article/cf8c2877f3424441a63e97e4ed53e2dd
Autor:
Katalin Solti, Wei-Li Kuan, Balázs Fórizs, Gergely Kustos, Judith Mihály, Zoltán Varga, Balázs Herberth, Éva Moravcsik, Róbert Kiss, Manuela Kárpáti, Anna Mikes, Yanyan Zhao, Tímea Imre, Jean-Christophe Rochet, Franklin Aigbirhio, Caroline H. Williams-Gray, Roger A. Barker, Gergely Tóth
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The loss of native function of the DJ-1 protein has been linked to the development of Parkinson's (PD) and other neurodegenerative diseases. Here we show that DJ-1 aggregates into β-sheet structured soluble and fibrillar aggregates in vitro under ph
Externí odkaz:
https://doaj.org/article/c118d4f98c9b470dac01ee0fb27ed0a7
Autor:
Manodoro, Floriana *, Marzec, Jacek *, Wang, Jun *, Chaplin, Tracy *, Jovanovic, Jelena V *, Eva, Moravcsik *, Sameena, Iqbal *, Grimwade, David, Gribben, John, Young, Bryan D, Debernardi, Silvana *
Publikováno v:
In Blood 15 November 2013 122(21):2494-2494