Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Eva Morán-Salvador"'
Autor:
Concepció Soler, Sagrario Ortega, Carmen Benito, Sara Sancho, Miquel Borràs, Gemma Tarancón, Nuria Vázquez-Villoldo, Eva Morán-Salvador, Arnau Viña-Vilaseca, Bàrbara Castellana, Joan Manils, David Parra
Supplementary Figure Legend, Tables 1-2 from Increased Susceptibility to Skin Carcinogenesis in TREX2 Knockout Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0f91436c3b66d8cd570d2833cefcae
https://doi.org/10.1158/0008-5472.22378385.v1
https://doi.org/10.1158/0008-5472.22378385.v1
Autor:
Concepció Soler, Sagrario Ortega, Carmen Benito, Sara Sancho, Miquel Borràs, Gemma Tarancón, Nuria Vázquez-Villoldo, Eva Morán-Salvador, Arnau Viña-Vilaseca, Bàrbara Castellana, Joan Manils, David Parra
Supplementary Figure 1 from Increased Susceptibility to Skin Carcinogenesis in TREX2 Knockout Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ba17d6a4cf5507d132f9fe07d67ba9
https://doi.org/10.1158/0008-5472.22378388
https://doi.org/10.1158/0008-5472.22378388
Autor:
Jelena Mann, Eva Morán-Salvador
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Liver fibrosis arises because prolonged injury combined with excessive scar deposition within hepatic parenchyma arising from overactive wound healing response mediated by activated myofibroblasts. Fibrosis is the common end point for any type of chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38caeabad81e2e91991398be66d0e5a5
https://doi.org/10.1016/j.jcmgh.2017.04.007
https://doi.org/10.1016/j.jcmgh.2017.04.007
Autor:
Amber Knox, Jelena Mann, Marina García-Macia, Laura Sabater, Eva Morán-Salvador, Agata Page, Fiona Oakley, Marco Y W Zaki, Saimir Luli, Ashwin Sivaharan, Derek A. Mann
Publikováno v:
Gastroenterology
Background & Aims Methyl-CpG binding protein 2, MECP2, which binds to methylated regions of DNA to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is required for development of liver fibrosis in mice. We investigated the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e6380589c589bd9e568baeb0c14dfc
https://pubmed.ncbi.nlm.nih.gov/31352003
https://pubmed.ncbi.nlm.nih.gov/31352003
Autor:
Agata Page, Jelena Mann, Graham Smith, Eva Morán-Salvador, Pier P. Paoli, Derek A. Mann, Fiona Oakley, Rachel Howarth
Publikováno v:
Hepatology. 62:874A-903A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8cf7abfae1c4dfde44bbe777e883072
https://doi.org/10.1002/hep.28230
https://doi.org/10.1002/hep.28230
Autor:
Cristina López-Vicario, Yaacov Barak, Joan Clària, Esther Titos, Vicente Arroyo, Rosa Miquel, Ana González-Périz, Eva Morán-Salvador, Verónica García-Alonso, Bibiana Rius
Publikováno v:
Journal of Hepatology. 59:1045-1053
Background & Aims PPARγ plays an essential role in the transcriptional regulation of genes involved in lipid and glucose metabolism, insulin sensitivity, and inflammation. We recently demonstrated that PPARγ plays a causative role in hepatocyte lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e29e6263a77067c3cf5aaa44b4f042
https://doi.org/10.1016/j.jhep.2013.06.023
https://doi.org/10.1016/j.jhep.2013.06.023
Autor:
Verónica García-Alonso, Montserrat Cofán, Ana González-Périz, Eva Morán-Salvador, Juan José Lozano, Cristina López-Vicario, Esther Titos, Jing X. Kang, Vicente Arroyo, Bibiana Rius, Ramon Bataller, Joan Clària
Publikováno v:
Gut. 63:344-355
Objective The mechanisms underlying non-alcoholic steatohepatitis (NASH) are not completely elucidated. In the current study we integrated gene expression profiling of liver biopsies from NASH patients with translational studies in mouse models of st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a69c3335ac07c798a83e95c2750863
https://doi.org/10.1136/gutjnl-2012-303179
https://doi.org/10.1136/gutjnl-2012-303179
Autor:
Ana González-Périz, Marcos Martínez-Clemente, Verónica García-Alonso, Eva Morán-Salvador, Joan Clària, Vicente Arroyo, Esther Titos, Marta López-Parra, Cristina López-Vicario, Yaacov Barak
Publikováno v:
The FASEB Journal. 25:2538-2550
Peroxisome proliferator-activated receptor (PPAR) γ is a nuclear receptor central to glucose and lipid homeostasis. PPARγ role in nonalcoholic fatty liver disease is controversial because PPARγ overexpression is a general property of steatotic liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7df5699460a394d9bd53e88a006787
https://doi.org/10.1096/fj.10-173716
https://doi.org/10.1096/fj.10-173716
Autor:
Sagrario Ortega, Arnau Viña-Vilaseca, Sara Sancho, Eva Morán-Salvador, Nuria Vázquez-Villoldo, Bàrbara Castellana, Joan Manils, Carmen Zamorano Benito, Gemma Tarancón, Concepció Soler, Miquel Borràs, David Parra
Publikováno v:
Cancer Research. 69:6676-6684
TREX2 is a proofreading 3′-5′ exonuclease that can be involved in genome maintenance; however, its biological role remains undefined. To better understand the function and physiologic relevance of TREX2, we generated mice deficient in TREX2 by ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22db01cbf123fde65c27cba14f81fdc6
https://doi.org/10.1158/0008-5472.can-09-1208
https://doi.org/10.1158/0008-5472.can-09-1208
Autor:
Esther Titos, Vicente Arroyo, Eva Morán-Salvador, Ana González-Périz, Joan Clària, Marcos Martínez-Clemente, Marta López-Parra, Karsten Gronert, Natàlia Ferré, Raquel Horrillo, Baiyan Dong
Publikováno v:
The FASEB Journal. 23:1946-1957
Omega-3-polyunsaturated fatty acids (ω-3-PUFAs) have well-documented protective effects that are attributed not only to eicosanoid inhibition but also to the formation of novel biologically active lipid mediators (i.e., resolvins and protectins). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55ec11e570230f9758481641e3cbfa5
https://doi.org/10.1096/fj.08-125674
https://doi.org/10.1096/fj.08-125674