Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Eva M. Sturm"'
Autor:
Sonja Rittchen, Katharina Jandl, Ilse Lanz, Bernhard Reiter, Nerea Ferreirós, Daniel Kratz, Jörg Lindenmann, Luka Brcic, Thomas Bärnthaler, Reham Atallah, Horst Olschewski, Eva M. Sturm, Akos Heinemann
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11697 (2021)
Acute respiratory inflammation, most commonly resulting from bacterial or viral infection, is one of the leading causes of death and disability worldwide. The inflammatory lipid mediator prostaglandin D2 (PGD2) and its rate-limiting enzyme, hematopoi
Externí odkaz:
https://doaj.org/article/e9e36f38b12b402baa50c259a38526ee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5431 (2021)
Endocannabinoids (eCBs) are lipid-based retrograde messengers with a relatively short half-life that are produced endogenously and, upon binding to the primary cannabinoid receptors CB1/2, mediate multiple mechanisms of intercellular communication wi
Externí odkaz:
https://doaj.org/article/321ec4371ef64d14aa2039eacaa2292d
Publikováno v:
Frontiers in Medicine, Vol 4 (2017)
Of the known prostanoid receptors, human eosinophils express the prostaglandin D2 (PGD2) receptors DP1 [also D-type prostanoid (DP)] and DP2 (also chemoattractant receptor homologous molecule, expressed on Th2 cells), the prostaglandin E2 receptors E
Externí odkaz:
https://doaj.org/article/3da2d1e3cef44c2eb8c64489b077752e
Autor:
Melanie Kienzl, Akos Heinemann, Gunther Marsche, Athina Trakaki, Eva Knuplez, Rudolf Schicho, Eva M. Sturm
Publikováno v:
British Journal of Pharmacology. 178:1234-1248
Background and purpose Miltefosine is an alkylphosphocholine drug with proven effectiveness against various types of parasites and cancer cells. Miltefosine is not only able to induce direct parasite killing but also modulates host immunity, for exam
Autor:
Eva M. Sturm, Leigh Marsh, Grazyna Kwapiszewska, Mathias Hochgerner, Horst Olschewski, Diana Schnoegl
Publikováno v:
Allergy and immunology.
Autor:
Leigh Marsh, Eva M. Sturm, Mathias Hochgerner, Horst Olschewski, Grazyna Kwapiszewska, Diana Schnoegl
Publikováno v:
Allergy. 77(3)
Background High-altitude therapy has been used as add-on treatment for allergic asthma with considerable success. However, the underlying mechanisms remain unclear. In order to investigate the possible therapeutic effects of high-altitude therapy on
Autor:
Andreas Eherer, Rudolf Schicho, Veronika Pommer, Magdalena Grill, Eva M. Sturm, F Durchschein, Christoph Högenauer, Cord Langner
Publikováno v:
Digestive Diseases and Sciences
Background The prostaglandin D2 receptor DP2 has been implicated in eosinophil infiltration and the development of eosinophilic esophagitis (EoE). Aims and Methods In this study, we investigated an involvement of PGE2 (EP1–EP4) and PGD2 (DP1) recep
Publikováno v:
Airway pharmacology and treatment.
Anti-inflammatory properties of synthetic and endogenous Rev-Erb-alpha agonists. Background: Asthma is an inflammatory disease with a strong circadian signature. Symptoms of asthma are worse overnight and in the early hours of the morning. Clock gene
Autor:
Gunter J Sturm, Chunsheng Jin, Bettina Kranzelbinder, Wolfgang Hemmer, Eva M Sturm, Antonia Griesbacher, Akos Heinemann, Jutta Vollmann, Friedrich Altmann, Karl Crailsheim, Margarete Focke, Werner Aberer
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20842 (2011)
BACKGROUND: Double sensitization (DS) to bee and vespid venom is frequently observed in the diagnosis of hymenoptera venom allergy, but clinically relevant DS is rare. Therefore it is sophisticated to choose the relevant venom for specific immunother
Externí odkaz:
https://doaj.org/article/d0d26ffb1c1b44e097d43ffe382b758c
Autor:
Akos Heinemann, Johannes Pilic, Petra Luschnig, David Roula, Melanie Kienzl, Reham Atallah, Eva M. Sturm
Publikováno v:
Biochemical Pharmacology. 192:114690
Background Eosinophilic asthma is increasingly recognized as one of the most severe and difficult-to-treat asthma subtypes. The JAK/STAT pathway is the principal signaling mechanism for a variety of cytokines and growth factors involved in asthma. Ho