Infant Gut Microbial Metagenome Mining of α-l-Fucosidases with Activity on Fucosylated Human Milk Oligosaccharides and Glycoconjugates

Autor: Eva M. Moya-Gonzálvez, Nazaret Peña-Gil, Antonio Rubio-del-Campo, José M. Coll-Marqués, Roberto Gozalbo-Rovira, Vicente Monedero, Jesús Rodríguez-Díaz, María J. Yebra

Publikováno v: Microbiology Spectrum, Vol 10, Iss 4 (2022)

ABSTRACT The gastrointestinal microbiota members produce α-l-fucosidases that play key roles in mucosal, human milk, and dietary oligosaccharide assimilation. Here, 36 open reading frames (ORFs) coding for putative α-l-fucosidases belonging to glyc

Externí odkaz: https://doaj.org/article/240e59f3f81545b99c9309961295dac0

Infant-gut associated Bifidobacterium dentium strains utilize the galactose moiety and release lacto-N-triose from the human milk oligosaccharides lacto-N-tetraose and lacto-N-neotetraose

Autor: María J. Yebra, Eva M. Moya-Gonzálvez, Jesús Rodríguez-Díaz, Antonio Rubio-del-Campo

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
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Much evidence suggests a role for human milk oligosaccharides (HMOs) in establishing the infant microbiota in the large intestine, but the response of particular bacteria to individual HMOs is not well known. Here twelve bacterial strains belonging t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d0f0e170ef0414416de18563ac5960
https://doaj.org/article/ea24167ed60949bbbe92c657aea48d0a

Infant gut microbiota modulation by human milk disaccharides in humanized microbiome mice

Autor: María J. Yebra, Jesús Rodríguez-Díaz, Roberto Gozalbo-Rovira, Antonio Rubio-del-Campo, Eva M. Moya-Gonzálvez, Juan Alberola

Publikováno v: Rubio-Del-Campo, Antonio Gozalbo Rovira, Roberto Vicente Moya-Gonzálvez, Eva M. Alberola Enguídanos, Juan Rodríguez Díaz, Jesús Yebra Yebra, María Jesús 2021 Infant gut microbiota modulation by human milk disaccharides in humanized microbiome mice Gut Microbes 13 1:e1914377 1 20
RODERIC: Repositorio Institucional de la Universitat de Valéncia
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Gut Microbes, Vol 13, Iss 1 (2021)
Gut Microbes
article-version (VoR) Version of Record
RODERIC. Repositorio Institucional de la Universitat de Valéncia
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC

Human milk glycans present a unique diversity of structures that suggest different mechanisms by which they may affect the infant microbiome development. A humanized mouse model generated by infant fecal transplantation was utilized here to evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f420a327c5e7c6fdbc2aea0be84718
https://doi.org/10.1080/19490976.2021.1914377