Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Eva M. Hoffmann"'
Autor:
Peter Ulz, Barbara Günther, Jochen B. Geigl, Thomas Schwarzbraun, Michael R. Speicher, Julie Waldispuehl-Geigl, Hans-Christoph Duba, Martina Auer, Eva M. Hoffmann, Anna C. Obenauf
Publikováno v:
Journal of Cellular and Molecular Medicine
The analysis of structural variants associated with specific phenotypic features is promising for the elucidation of the function of involved genes. There is, however, at present no approach allowing the rapid mapping of chromosomal translocation bre
Autor:
Elvira Peit, Kodandaramireddy Nalapareddy, Michael R. Speicher, Eva M. Hoffmann, Hans A. Kestler, Anna C. Obenauf, Esther Danenberg, K. Lenhard Rudolph, Yvonne Begus-Nahrmann, Nick Barker, André Lechel, Peter Schirmacher, Falk Schlaudraff, Birgit Liss, Hans Clevers
Publikováno v:
Nature Genetics, 41(10), 1138-1143. Nature Publishing Group
Telomere dysfunction limits the proliferative capacity of human cells and induces organismal aging by activation of p53 and p21. Although deletion of p21 elongates the lifespan of telomere-dysfunctional mice, a direct analysis of p53 in telomere-rela
Autor:
Carolin Lackner, Peter Ulz, Sumitra Mohan, Christin Gasch, Martina Auer, Klaus Pantel, Julie Waldispuehl-Geigl, Jochen B. Geigl, Ellen Heitzer, Gerald Höfler, Eva M. Hoffmann, Gunda Pristauz, Martin Pichler, Oliver Mauermann, Edgar Petru, Heinz Sill, Sabine Riethdorf, Sigurd Lax, Hellmut Samonigg, Florian Eisner, Thomas Bauernhofer, Michael R. Speicher
Publikováno v:
International Journal of Cancer
International Journal of Cancer. Journal International du Cancer
International Journal of Cancer; Vol 133
International Journal of Cancer. Journal International du Cancer
International Journal of Cancer; Vol 133
With the increasing number of available predictive biomarkers, clinical management of cancer is becoming increasingly reliant on the accurate serial monitoring of tumor genotypes. We tested whether tumor-specific copy number changes can be inferred f
Autor:
Jochen B. Geigl, Gerald Höfler, Sabine Riethdorf, Carolin Lackner, Florian Eisner, Ellen Heitzer, Heinz Sill, Sigurd Lax, Christin Gasch, Klaus Pantel, Oliver Mauermann, Martin Pichler, Martina Auer, Peter Ulz, Julie Waldispuehl-Geigl, Eva M. Hoffmann, Hellmut Samonigg, Thomas Bauernhofer, Michael R. Speicher
Publikováno v:
Cancer Research; Vol 73
Circulating tumor cells (CTC) released into blood from primary cancers and metastases reflect the current status of tumor genotypes, which are prone to changes. Here, we conducted the first comprehensive genomic profiling of CTCs using array–compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1089b34bc1771713e80adfc14d8f6665
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/104633
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/104633
Autor:
Michael Schenk, Hilde Urnauer, Sarah J. Harper, Eva M. Hoffmann, Gunnar Jaehnichen, Stephan A. Schug
Publikováno v:
Pocket Guide Pain Management ISBN: 9783540329961
In Germany an estimated 5 million people (8% of the population) suffer from chronic pain. Worldwide, the prevalence of chronic benign pain ranges between 2% and 40% of the population, depending on the study. In the USA, the rate of disability claims
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa41e23fa44315f42c1963b7be90f7e8
https://doi.org/10.1007/978-3-540-32997-8_1
https://doi.org/10.1007/978-3-540-32997-8_1
Autor:
Sarah–Fee Katz, André Lechel, Birgit Liss, Daniel Hartmann, Johann M. Kraus, Peter Schirmacher, K. Lenhard Rudolph, Parisa Eshraghi, Eva M. Hoffmann, Hans A. Kestler, Johanna Duda, Yvonne Begus Nahrmann, Michael R. Speicher, Anna C. Obenauf
Publikováno v:
Gastroenterology. 142:1229-1239.e3
Background & Aims p53 limits the self-renewal of stem cells from various tissues. Loss of p53, in combination with other oncogenic events, results in aberrant self-renewal and transformation of progenitor cells. It is not known whether loss of p53 is