Výsledky vyhledávání - "Eva M Sánchez-Robles"

Promising biomedical subcutaneous delivery system in opioid disaccustom process: In vitro/in vivo evaluation of naloxone microparticles on antagonist effect of morphine

Autor: M Cristina Benéitez García, Rocío Girón Moreno, Inés Colmena Crespo, Rosalía M Díez-Orejas, M Isabel Martín Fontelles, Carlos Goicoechea García, Eva M Sánchez-Robles, M Esther Gil-Alegre

Publikováno v: International Journal of Pharmaceutics. 635:122766

The addiction induced by the misuse of opioids, is not only a public health emergency but also a social and economic welfare. The main therapy is based on opioid antagonists. Oral and injectable naltrexone administration is the most widely used, pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa7db5287afb8a38ebfa0060523e865
https://doi.org/10.1016/j.ijpharm.2023.122766

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Monoclonal Antibodies for Chronic Pain Treatment: Present and Future

Autor: Nancy Paniagua, Carmen Rodríguez-Rivera, Rocío Girón, David Pascual, Carlos Goicoechea, Eva M. Sánchez-Robles

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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International Journal of Molecular Sciences, Vol 22, Iss 10325, p 10325 (2021)
International Journal of Molecular Sciences

Chronic pain remains a major problem worldwide, despite the availability of various non-pharmacological and pharmacological treatment options. Therefore, new analgesics with novel mechanisms of action are needed. Monoclonal antibodies (mAbs) are dire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d9626dc0b44be10358f3dec5080469
http://hdl.handle.net/10261/252795

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SGK1.1 isoform is involved in nociceptive modulation, offering a protective effect against noxious cold stimulus in a sexually dimorphic manner

Autor: Carlos Goicoechea, Nancy Paniagua, Eva M. Sánchez-Robles, Rocío Girón, Teresa Giraldez, Eva Mercado, Diego Alvarez de la Rosa

Publikováno v: BURJC-Digital. Repositorio Institucional de la Universidad Rey Juan Carlos
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Digital.CSIC. Repositorio Institucional del CSIC

The serum and glucocorticoid-regulated kinase 1 (SGK1) is a widely expressed protein in the Central Nervous System (CNS), involved in regulating the activity of a wide variety of ion channels and transporters and phys- iological functions, such as ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893151d1f16b3df62900567a3455a087
http://hdl.handle.net/10115/19106

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Characterization of the nociceptive effect of carrageenan: Masseter versus gastrocnemius

Autor: Jesús Esteban-Hernández, Eva M. Sánchez-Robles, Ana Bagüés, M a Isabel Martín‐Fontelles

Publikováno v: Muscle & Nerve. 56:804-813

Introduction To better understand the pathophysiology of chronic muscle pain, there are multiple animal models that mimic different acute/chronic pain conditions, such as carrageenan injection. Our previous studies demonstrated differences between mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4c5231f6cdb5fb8becd05683e69782
https://doi.org/10.1002/mus.25538

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Comparison of the antinociceptive profiles of morphine and oxycodone in two models of inflammatory and osteoarthritic pain in rat

Autor: Miguel M. Garcia, Martín Avellanal, Carlos Goicoechea, Susana Traseira, M.I. Martin, Eva M. Sánchez-Robles

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Oxycodone and morphine are two opioid drugs commonly used for the treatment of moderate to severe pain. However, their use in the management of noncancer pain remains a controversial issue and, in this respect, the evidence on their effectiveness and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151c554e23539e21d9057670d74c264c
https://pubmed.ncbi.nlm.nih.gov/30978319

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Involvement of central and peripheral cannabinoid receptors on antinociceptive effect of tetrahydrocannabinol in muscle pain

Autor: Ana Bagüés, M. Isabel Martin, Eva M. Sánchez-Robles

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Cannabinoid (CB) receptors have emerged as an attractive therapeutic target for pain management in recent years and the interest in the use of cannabinoids is gradually increasing, particularly in patients where conventional treatments fail. Muscle p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac0818b0ae03a54f1751f3dc7208c4e
https://doi.org/10.1016/j.ejphar.2014.10.016

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