A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair

Autor: Patricia Peking, Ulrich Koller, Stefan Hainzl, Sophie Kitzmueller, Thomas Kocher, Elisabeth Mayr, Alexander Nyström, Thomas Lener, Julia Reichelt, Johann W Bauer, Eva M Murauer

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)

RNA trans-splicing represents an auspicious option for the correction of genetic mutations at RNA level. Mutations within COL7A1 causing strong reduction or absence of type VII collagen are associated with the severe skin blistering disease dystrophi

Externí odkaz: https://doaj.org/article/7415625472d94827a1e3e8761f7d7ce9

Supplementary Figure 1 from Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells

Autor: Johann W. Bauer, Helmut Hintner, Guerrino Meneguzzi, Leena Bruckner-Tuderman, Ulrich Koller, Elisabeth Mayr, Eva M. Murauer, Iris K. Gratz, Christina Gruber

Supplementary Figure 1 from Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c560b823d3bc3c3c73fa37bd046e33ba
https://doi.org/10.1158/1535-7163.22497184

Supplementary Figure Legends from Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells

Autor: Johann W. Bauer, Helmut Hintner, Guerrino Meneguzzi, Leena Bruckner-Tuderman, Ulrich Koller, Elisabeth Mayr, Eva M. Murauer, Iris K. Gratz, Christina Gruber

Supplementary Figure Legends from Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a647257b304c27cc417b1c9ff13e361
https://doi.org/10.1158/1535-7163.22497178

A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin

Autor: Angelika Stoecklinger, Iris K. Gratz, Eva M. Murauer, Raimund Holly, Daniel J. Campbell, Jutta Horejs-Hoeck, Ariane Benedetti, Maria M. Klicznik, Suraj R Varkhande, Andreas Sir, Roland Reitsamer, Martin Laimer, Laura M Gail, Theresa Neuper, Michael Rosenblum

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports

Human skin contains a population of memory T cells that supports tissue homeostasis and provides protective immunity. The study of human memory T cells is often restricted to in vitro studies and to human PBMC serving as primary cell source. Because

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522f8c2791c029a1a1733c7547061ca0
http://link.springer.com/article/10.1038/s41598-020-67430-7

First Identification of RNA-Binding Proteins That Regulate Alternative Exons in the Dystrophin Gene

Autor: Mireille Claustres, Anne-Laure Bougé, Michel Koenig, Dylan Da Cunha, Julie Miro, Emmanuelle Beyne, Eva M. Murauer, Sylvie Tuffery-Giraud

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (20), pp.7803. ⟨10.3390/ijms21207803⟩
International Journal of Molecular Sciences, Vol 21, Iss 7803, p 7803 (2020)
Volume 21
Issue 20

International audience; The Duchenne muscular dystrophy (DMD) gene has a complex expression pattern regulated by multiple tissue-specific promoters and by alternative splicing (AS) of the resulting transcripts. Here, we used an RNAi-based approach co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951509ceb8d15f49c6472493a8a42079
https://pubmed.ncbi.nlm.nih.gov/33096920