Rbm20ΔRRM Mice, Expressing a Titin Isoform with Lower Stiffness, Are Protected from Mechanical Ventilation-Induced Diaphragm Weakness

Autor: Marloes van den Berg, Eva L. Peters, Robbert J. van der Pijl, Shengyi Shen, Leo M. A. Heunks, Henk L. Granzier, Coen A. C. Ottenheijm

Publikováno v: International Journal of Molecular Sciences, 23(24):15689. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15689
van den Berg, M, Peters, E L, van der Pijl, R J, Shen, S, Heunks, L M A, Granzier, H L & Ottenheijm, C A C 2022, ' Rbm20ΔRRM Mice, Expressing a Titin Isoform with Lower Stiffness, Are Protected from Mechanical Ventilation-Induced Diaphragm Weakness ', International Journal of Molecular Sciences, vol. 23, no. 24, 15689 . https://doi.org/10.3390/ijms232415689

Diaphragm weakness frequently develops in mechanically ventilated critically ill patients and is associated with increased morbidity, including ventilator weaning failure, mortality, and health care costs. The mechanisms underlying diaphragm weakness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5fe7c6b1294d73872d75072838afff
https://pure.eur.nl/en/publications/60d174d6-2e59-44e4-ab34-24928ef631be

Increased MAO-A activity promotes progression of pulmonary arterial hypertension

Autor: Denielli da Silva Goncalves Bos, Robert Szulcek, Frances S. de Man, Xiaoke Pan, Maria Catalina Gomez-Puerto, Willem J. van der Laarse, Ingrid Schalij, Anton Vonk Noordegraaf, Harm Jan Bogaard, Roy E. J. Schiepers, Eva L. Peters, Stine Andersen, Asger Andersen, Marie-José Goumans, Xiao-Qing Sun, Julie Birkmose Axelsen, Kondababu Kurakula

Publikováno v: Sun, X-Q, Peters, E L, Schalij, I, Axelsen, J B, Andersen, S, Kurakula, K, Gomez-Puerto, M C, Szulcek, R, Pan, X, da Silva Goncalves Bos, D, Schiepers, R E, Andersen, A, Goumans, M-J, Vonk Noordegraaf, A, van der Laarse, W J, de Man, F S & Bogaard, H J 2021, ' Increased MAO-A Activity Promotes Progression of Pulmonary Arterial Hypertension ', American Journal of Respiratory Cell and Molecular Biology (Online), vol. 64, no. 3, pp. 331-343 . https://doi.org/10.1165/rcmb.2020-0105OC
American Journal of Respiratory Cell and Molecular Biology, 64(3), 331-343. American Thoracic Society
Sun, X-Q, Peters, E L, Schalij, I, Axelsen, J B, Andersen, S, Kurakula, K, Gomez-Puerto, M C, Szulcek, R, Pan, X, da Silva Goncalves Bos, D, Schiepers, R E J, Andersen, A, Goumans, M-J, Noordegraaf, A V, van der Laarse, W J, de Man, F S & Bogaard, H J 2021, ' Increased MAO-A activity promotes progression of pulmonary arterial hypertension ', American Journal of Respiratory Cell and Molecular Biology, vol. 64, no. 3, pp. 331-343 . https://doi.org/10.1165/rcmb.2020-0105OC, https://doi.org/10.1165/rcmb.2020-0105OC
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology, 64(3), 331-343. AMER THORACIC SOC

Monoamine oxidases (MAOs), a class of enzymes bound to the outer mitochondrial membrane, are important sources of reactive oxygen species. Increased MAO-A activity in endothelial cells and cardiomyocytes contributes to vascular dysfunction and progre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17fc29d183ab7e6ceb1004764998e13
https://doi.org/10.1165/rcmb.2020-0105oc

Inhibition of monoamine oxidase A in pulmonary artery banding-induced right ventricular failure

Autor: Stine Andersen, Asger Andersen, Julie Birkmose Axelsen, Anton Vonk Noordegraaf, Ingrid Schalij, Frances Handoko de Man, Xiao-Qing Sun, Harm Jan Bogaard, Eva L Peters, Willem J. van der Laarse

Publikováno v: Journal of Molecular and Cellular Cardiology, 140, 25-25. Academic Press Inc.
Peters, E, Sun, X, Andersen, S, Axelsen, J B, Schalij, I, van der Laarse, W, Andersen, A, Bogaard, H J, Handoko-de Man, F & Noordegraaf, A V 2020, ' Inhibition of monoamine oxidase A in pulmonary artery banding-induced right ventricular failure ', Journal of Molecular and Cellular Cardiology, vol. 140, pp. 25-25 . https://doi.org/10.1016/j.yjmcc.2019.11.057

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315794fc17adef0e75d37d229a43d494
https://research.vumc.nl/en/publications/177b9821-32ac-4999-b797-e554b62ebac2

Meijer and Vloedman’s histochemical demonstration of mitochondrial coupling obeys Lambert–Beer’s law in the myocardium

Autor: Eva L Peters, David Comerford, Frédéric M. Vaz, Willem J. van der Laarse

Publikováno v: Histochemistry and cell biology, 151(1), 85-90. Springer Verlag
Histochemistry and Cell Biology
Peters, E L, Comerford, D, Vaz, F M & van der Laarse, W J 2019, ' Meijer and Vloedman's histochemical demonstration of mitochondrial coupling obeys Lambert-Beer's law in the myocardium ', Histochemistry and Cell Biology, vol. 151, no. 1, pp. 85-90 . https://doi.org/10.1007/s00418-018-1716-3
Histochemistry and Cell Biology, 151(1), 85-90. Springer Verlag

Uncoupling of mitochondrial proton pumping and adenosine triphosphate (ATP) production lowers mitochondrial efficiency. Current methods to determine mitochondrial efficiency require substantial amounts of tissue and permeabilization or isolation proc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa940d8545578236eaa23faaedd3d308
https://pure.amc.nl/en/publications/meijer-and-vloedmans-histochemical-demonstration-of-mitochondrial-coupling-obeys-lambertbeers-law-in-the-myocardium(a14b1224-4e94-4ed6-b80a-1b2453c4a2f6).html

Regulation of myoglobin in hypertrophied rat cardiomyocytes in experimental pulmonary hypertension

Autor: W. J. Van Der Laarse, D. Kos, Carla Offringa, Richard T. Jaspers, Eva L Peters

Publikováno v: Peters, E L, Offringa, C, Kos, D, Van der Laarse, W J & Jaspers, R T 2016, ' Regulation of myoglobin in hypertrophied rat cardiomyocytes in experimental pulmonary hypertension ', Pflügers Archiv European Journal of Physiology, vol. 468, no. 10, pp. 1697-1707 . https://doi.org/10.1007/s00424-016-1865-y
Pflugers Archiv
Pflügers Archiv European Journal of Physiology, 468(10), 1697-1707. Springer Verlag

A major problem in chronic heart failure is the inability of hypertrophied cardiomyocytes to maintain the required power output. A Hill-type oxygen diffusion model predicts that oxygen supply is limiting in hypertrophied cardiomyocytes at maximal rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1baf56962422d96666d19d7c7a1a5094
https://doi.org/10.1007/s00424-016-1865-y