Genome wide association study of clinical duration and age at onset of sporadic CJD.

Autor: Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G Kovacs, Michael D Geschwind, Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J van der Lee, Cornelia M van Duijn, Pawel P Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Stéphane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr, Brian S Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead

Publikováno v: PLoS ONE, Vol 19, Iss 7, p e0304528 (2024)

Human prion diseases are rare, transmissible and often rapidly progressive dementias. The most common type, sporadic Creutzfeldt-Jakob disease (sCJD), is highly variable in clinical duration and age at onset. Genetic determinants of late onset or slo

Externí odkaz: https://doaj.org/article/a8105e366d44473aa02be9676f81d759

Neurological Complications in COVID-19 Patients: Can Analysis of Specific Antibodies and Viral RNA in Paired Cerebrospinal Fluid and Serum be Used for Accurate Diagnosis of SARS-CoV-2 Neuroinflammatory Disease? A Case Series

Autor: Karin Holst Lauridsen, Kristine Boisen Olsen, Eva Løbner Lund, Tomas O Jensen, Thomas Ingemann Pedersen, Zitta Barrella Harboe, Valeria Antsupova, Lasse Dam Rasmussen, Dennis Röser, Jytte Banner, Kristina Træholt Franck, Veronika Vorobieva Solholm Jensen

Publikováno v: Clinical Pathology, Vol 15 (2022)

Background: Neurological complications during and after SARS-CoV-2 infection have been frequently described. The detection of either SARS-CoV-2 RNA or specific antibodies against SARS-CoV-2 in cerebrospinal fluid in the context of concomitant neurolo

Externí odkaz: https://doaj.org/article/649caefb37ed4ea6b55ac72722c4d67c

Postprocessing of MRIs Using FreeSurfer in Epilepsy Surgery Patients Provides an Excellent Imaging Marker of Hippocampal Sclerosis but Fails to Separate Subtypes

Autor: Ane G. Kloster, Giske Opheim, Kristin Å. Alfstad, Karen B. Larsen, Pitt Niehusmann, Emil Holm, Philip Fink-Jensen, Eva Løbner Lund, Bo Jespersen, Jugoslav Ivanovic, Guido Rubboli, Camilla G. Madsen, Pål B. Marthinsen, Melanie Ganz, Morten Lossius, Lars H. Pinborg

Publikováno v: Kloster, A G, Opheim, G, Alfstad, K, Larsen, K B, Niehusmann, P, Holm, E, Fink-Jensen, P, Lund, E L, Jespersen, B, Ivanovic, J, Rubboli, G, Madsen, C G, Marthinsen, P B, Ganz, M, Lossius, M & Pinborg, L H 2023, ' Postprocessing of MRIs Using FreeSurfer in Epilepsy Surgery Patients Provides an Excellent Imaging Marker of Hippocampal Sclerosis but Fails to Separate Subtypes ', Acta Neurologica Scandinavica, vol. 2023, 2366355 . https://doi.org/10.1155/2023/2366355

Objective. Histopathological examinations will diminish as minimally invasive epilepsy surgery increasingly replaces open surgery. The objective of this study was to test if visual and computer-aided quantitative analyses of presurgical high-quality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0953e159ec6d4958473fa746ca488e
https://curis.ku.dk/portal/da/publications/postprocessing-of-mris-using-freesurfer-in-epilepsy-surgery-patients-provides-an-excellent-imaging-marker-of-hippocampal-sclerosis-but-fails-to-separate-subtypes(ad84ecd5-f7ff-42b1-927a-c89e3cf35c81).html

Perspective: targeting VEGF-A and YKL-40 in glioblastoma – matter matters

Autor: Petra Hamerlik, Eva Løbner Lund, Kristoffer Vitting-Seerup, Elisabeth Anne Adanma Obara, Hans Skovgaard Poulsen, Jane Skjøth-Rasmussen, Henriette Pedersen, Julia S. Johansen, Kamilla E. Jensen, Camilla Bjørnbak Holst

Publikováno v: Cell Cycle
article-version (VoR) Version of Record
Holst, C B, Pedersen, H, Obara, E A A, Vitting-Seerup, K, Jensen, K E, Skjøth-Rasmussen, J, Lund, E L, Poulsen, H S, Johansen, J S & Hamerlik, P 2021, ' Perspective : targeting VEGF-A and YKL-40 in glioblastoma–matter matters ', Cell Cycle, vol. 20, no. 7, pp. 702-715 . https://doi.org/10.1080/15384101.2021.1901037

Glioblastomas (GBM) are heterogeneous highly vascular brain tumors exploiting the unique microenvironment in the brain to resist treatment and anti-tumor responses. Anti-angiogenic agents, immunotherapy, and targeted therapy have been studied extensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455c7e1e0ae71ee8c04676ce6038a836
http://europepmc.org/articles/PMC8078714

ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance

Autor: Aniello Federico, Christian Thomas, Katarzyna Miskiewicz, Niklas Woltering, Francesca Zin, Karolina Nemes, Brigitte Bison, Pascal D. Johann, Debra Hawes, Susanne Bens, Uwe Kordes, Steffen Albrecht, Hildegard Dohmen, Peter Hauser, Kathy Keyvani, Frank K. H. van Landeghem, Eva Løbner Lund, David Scheie, Christian Mawrin, Camelia-Maria Monoranu, Benedicte Parm Ulhøi, Torsten Pietsch, Harald Reinhard, Markus J. Riemenschneider, Astrid Sehested, David Sumerauer, Reiner Siebert, Werner Paulus, Michael C. Frühwald, Marcel Kool, Martin Hasselblatt

Publikováno v: Federico, A, Thomas, C, Miskiewicz, K, Woltering, N, Zin, F, Nemes, K, Bison, B, Johann, P D, Hawes, D, Bens, S, Kordes, U, Albrecht, S, Dohmen, H, Hauser, P, Keyvani, K, van Landeghem, F K H, Lund, E L, Scheie, D, Mawrin, C, Monoranu, C M, Parm Ulhøi, B, Pietsch, T, Reinhard, H, Riemenschneider, M J, Sehested, A, Sumerauer, D, Siebert, R, Paulus, W, Frühwald, M C, Kool, M & Hasselblatt, M 2022, ' ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance ', Acta Neuropathologica, vol. 143, no. 6, pp. 697-711 . https://doi.org/10.1007/s00401-022-02424-5
Federico, A, Thomas, C, Miskiewicz, K, Woltering, N, Zin, F, Nemes, K, Bison, B, Johann, P D, Hawes, D, Bens, S, Kordes, U, Albrecht, S, Dohmen, H, Hauser, P, Keyvani, K, van Landeghem, F K H, Lund, E L, Scheie, D, Mawrin, C, Monoranu, C-M, Parm Ulhøi, B, Pietsch, T, Reinhard, H, Riemenschneider, M J, Sehested, A, Sumerauer, D, Siebert, R, Paulus, W, Frühwald, M C, Kool, M & Hasselblatt, M 2022, ' ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance ', Acta Neuropathologica, vol. 143, no. 6, pp. 697-711 . https://doi.org/10.1007/s00401-022-02424-5

Atypical teratoid/rhabdoid tumor (ATRT) is an aggressive central nervous system tumor characterized by loss of SMARCB1/INI1 protein expression and comprises three distinct molecular groups, ATRT–TYR, ATRT–MYC and ATRT–SHH. ATRT–SHH represents

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b881aecb548b2ef7be6893d42d4a6b
https://pubmed.ncbi.nlm.nih.gov/35501487