Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eva Korytiaková"'
Autor:
Markus Hillmeier, Mirko Wagner, Timm Ensfelder, Eva Korytiakova, Peter Thumbs, Markus Müller, Thomas Carell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Mannosyl-queuosine (manQ) is a non-canonical RNA nucleoside present in the anticodon loop of certain tRNAs. Here, the authors use a combination of total synthesis and mass spectrometry to contradict the literature-reported structure and show that man
Externí odkaz:
https://doaj.org/article/2119a9a6818e481084ae1938daeef0a4
Publikováno v:
Angewandte Chemie. 133:23394-23398
Publikováno v:
Angewandte Chemie (International Ed. in English)
Cellular DNA is composed of four canonical nucleosides (dA, dC, dG and T), which form two Watson–Crick base pairs. In addition, 5‐methylcytosine (mdC) may be present. The methylation of dC to mdC is known to regulate transcriptional activity. Nex
Publikováno v:
Angewandte Chemie (International Ed. in English)
The epigenetic marker 5‐methyl‐2′‐deoxycytidine (5mdC) is the most prevalent modification to DNA. It is removed inter alia via an active demethylation pathway: oxidation by Ten‐Eleven Translocation 5‐methyl cytosine dioxygenase (TET) and
Publikováno v:
Angewandte Chemie. 133:17005-17010
Autor:
Ewelina Kaminska, Eveliina Ponkkonen, Sarah Schiffers, Alexander Schön, Eva Korytiaková, Thomas Carell, Florian Schelter
Publikováno v:
Angewandte Chemie. 132:5639-5643
Autor:
Alexander Schön, Eva Korytiaková, Florian Schelter, Thomas Carell, Sarah Schiffers, Ewelina Kaminska, Eveliina Ponkkonen
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie International Edition
The removal of 5‐methyl‐deoxycytidine (mdC) from promoter elements is associated with reactivation of the silenced corresponding genes. It takes place through an active demethylation process involving the oxidation of mdC to 5‐hydroxymethyl‐d
Publikováno v:
Angewandte Chemie-International Edition
Autor:
Olesea Kosmatchev, René Rahimoff, Gautier Arista, Yingqian Zhang, Angie Kirchner, Eva Korytiaková, Thomas Carell, Charlotte Ebert, Sarah Schiffers, Fabio Spada
Publikováno v:
Nature Chemical Biology
Epigenetic plasticity underpins cell potency, but the extent to which active turnover of DNA methylation contributes to such plasticity is not known, and the underlying pathways are poorly understood. Here we use metabolic labeling with stable isotop
Oxidative and non-oxidative active turnover of genomic methylcytosine in distinct pluripotent states
Autor:
Eva Korytiaková, Thomas Carell, Yingqian Zhang, Charlotte Ebert, Olesea Kosmatchev, René Rahimoff, Angie Kirchner, Sarah Schiffers, Fabio Spada
Epigenetic plasticity underpins cell potency, but the extent to which active turnover of DNA methylation contributes to such plasticity is not known and the underlying pathways are poorly understood. Here we use metabolic labelling with stable isotop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8197e5a9d4071fe020c1957318ab2b